Search Results - "Zhihai Peng"

LncRNA-ATB mediated E-cadherin repression promotes the progression of colon cancer and predicts poor prognosis by Yue, Ben, Qiu, Shenglong, Zhao, Senlin, Liu, Chenchen, Zhang, Dongyuan, Yu, Fudong, Peng, Zhihai, Yan, Dongwang

“…Long non-coding RNA-activated by TGF-β (lncRNA-ATB) promotes the invasion-metastasis cascade in hepatocellular carcinoma via downregulating E-cadherin (E-cad)…”
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TIMP1 is a prognostic marker for the progression and metastasis of colon cancer through FAK-PI3K/AKT and MAPK pathway by Song, Guohe, Xu, Shifeng, Zhang, Hong, Wang, Yupeng, Xiao, Chao, Jiang, Tao, Wu, Leilei, Zhang, Tao, Sun, Xing, Zhong, Lin, Zhou, Chongzhi, Wang, Zhaowen, Peng, Zhihai, Chen, Jian, Wang, Xiaoliang

“…Tissue inhibitor matrix metalloproteinase 1 (TIMP1) plays a vital role in carcinogenesis, yet its precise functional roles and regulation remain unclear. In…”
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miR-19b-3p promotes colon cancer proliferation and oxaliplatin-based chemoresistance by targeting SMAD4: validation by bioinformatics and experimental analyses by Jiang, Tao, Ye, Ling, Han, Zhongbo, Liu, Yuan, Yang, Yinxue, Peng, Zhihai, Fan, Junwei

“…As a disease with extremely complex molecular mechanisms, many deregulated miRNAs have been identified in colon cancer. Few studies have been performed by…”
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Long non-coding RNA MINCR aggravates colon cancer via regulating miR-708-5p-mediated Wnt/β-catenin pathway by Yu, Yang, Chang, Zhuo, Han, Chao, Zhuang, Lingling, Zhou, Chongzhi, Qi, Xiaosheng, Peng, Zhihai

“…[Display omitted] •MINCR knockdown hampered proliferation, migration, invasion and EMT process in CC cells.•MINCR mediated CC procession via the regulation of…”
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The loss of SHMT2 mediates 5-fluorouracil chemoresistance in colorectal cancer by upregulating autophagy by Chen, Jian, Na, Risi, Xiao, Chao, Wang, Xiao, Wang, Yupeng, Yan, Dongwang, Song, Guohe, Liu, Xueni, Chen, Jiayi, Lu, Huijun, Chen, Chunyan, Tang, Huamei, Zhuang, Guohong, Fan, Guangjian, Peng, Zhihai

“…5-Fluorouracil (5-FU)-based chemotherapy is the first-line treatment for colorectal cancer (CRC) but is hampered by chemoresistance. Despite its impact on…”
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Impaired AGO2/miR-185-3p/NRP1 axis promotes colorectal cancer metastasis by Liu, Xisheng, Meng, Xiaole, Peng, Xiao, Yao, Qianlan, Zhu, Fangming, Ding, Zhongyi, Sun, Hongze, Liu, Xueni, Li, Dan, Lu, Ying, Tang, Huamei, Li, Bin, Peng, Zhihai

“…Increasing evidence suggests that global downregulation of miRNA expression is a hallmark of human cancer, potentially due to defects in the miRNA processing…”
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USP11 promotes growth and metastasis of colorectal cancer via PPP1CA-mediated activation of ERK/MAPK signaling pathway by Sun, Hongze, Ou, Baochi, Zhao, Senlin, Liu, Xueni, Song, Liwei, Liu, Xisheng, Wang, Rangrang, Peng, Zhihai

“…USP11 is an ubiquitin-specific protease that plays an important role in tumor progression via different mechanisms. However, the expression and prognostic…”
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Polo-like kinase 3 inhibits glucose metabolism in colorectal cancer by targeting HSP90/STAT3/HK2 signaling by Ou, Baochi, Sun, Hongze, Zhao, Jingkun, Xu, Zhuoqing, Liu, Yuan, Feng, Hao, Peng, Zhihai

“…Polo-like kinase 3 (PLK3) has been documented as a tumor suppressor in several types of malignancies. However, the role of PLK3 in colorectal cancer (CRC)…”
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The Critical Role of Dysregulated FOXM1―PLAUR Signaling in Human Colon Cancer Progression and Metastasis by Li, Dawei, Wei, Ping, Peng, Zhihai, Huang, Chen, Tang, Huamei, Jia, Zhiliang, Cui, Jiujie, Le, Xiangdong, Huang, Suyun, Xie, Keping

“…The mammalian Forkhead Box (Fox) transcription factor FOXM1 is implicated in tumorigenesis including mouse intestinal cancer. However, the clinical…”
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A Novel FoxM1-Caveolin Signaling Pathway Promotes Pancreatic Cancer Invasion and Metastasis by CHEN HUANG, ZHENGJUN QIU, LIWEI WANG, ZHIHAI PENG, ZHILIANG JIA, LOGSDON, Craig D, XIANGDONG LE, DAOYAN WEI, SUYUN HUANG, KEPING XIE

“…Caveolin-1 (Cav-1), a principal structural component of caveolar membrane domains, contributes to cancer development but its precise functional roles and…”
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Keratin 80 promotes migration and invasion of colorectal carcinoma by interacting with PRKDC via activating the AKT pathway by Li, Changcan, Liu, Xisheng, Liu, Yuan, Liu, Xueni, Wang, Rangrang, Liao, Jianhua, Wu, Shaohan, Fan, Junwei, Peng, Zhihai, Li, Bin, Wang, Zhaowen

“…Little is known about the function of Keratin 80 (KRT80), an epithelial keratin, in cancer. This study investigated the role of KRT80 in the prognosis of…”
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Application of 3‐Dimensional Printing in Pediatric Living Donor Liver Transplantation: A Single‐Center Experience by Wang, Pusen, Que, Weitao, Zhang, Mingman, Dai, Xiaoke, Yu, Kanru, Wang, Chunguang, Peng, Zhihai, Zhong, Lin

“…Three‐dimensional (3D) printing has been used to support organ transplantations. However, whether it helps remains unclear. This study aimed to present and…”
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Global burden of primary liver cancer by five etiologies and global prediction by 2035 based on global burden of disease study 2019 by Liu, Yuan, Zheng, Jinxin, Hao, Jialing, Wang, Rang Rang, Liu, Xueni, Gu, Peng, Yu, Hongwei, Yu, Yang, Wu, Chuanxing, Ou, Baochi, Peng, Zhihai

“…Background Using data from the global burden of disease (GBD) between 1990 and 2019 to report the leading etiological factors and hazards for liver cancer by…”
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STYK1 promotes epithelial-mesenchymal transition and tumor metastasis in human hepatocellular carcinoma through MEK/ERK and PI3K/AKT signaling by Wang, Zhaowen, Qu, Lei, Deng, Biao, Sun, Xing, Wu, Shaohan, Liao, Jianhua, Fan, Junwei, Peng, Zhihai

“…Serine/threonine/tyrosine kinase 1 (STYK1) is known to be involved in tumor progression. However, its molecular role and mechanism in hepatocellular carcinoma…”
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The prognostic value of the GPAT/AGPAT gene family in hepatocellular carcinoma and its role in the tumor immune microenvironment by Wen, Peizhen, Wang, Rui, Xing, Yiqun, Ouyang, Wanxin, Yuan, Yixin, Zhang, Shuaishuai, Liu, Yuan, Peng, Zhihai

“…Liver cancer is the sixth most commonly diagnosed cancer and the third leading cause of cancer-related death worldwide. Hepatocellular carcinoma accounts for…”
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SPTAN1/NUMB axis senses cell density to restrain cell growth and oncogenesis through Hippo signaling by Su, Dongxue, Li, Yuxi, Zhang, Weiji, Gao, Huan, Cheng, Yao, Hou, Yongqiang, Li, Junhong, Ye, Yi, Lai, Zhangjian, Li, Zhe, Huang, Haitao, Li, Jiaxin, Li, Jinhuan, Cheng, Mengyu, Nian, Cheng, Wu, Na, Zhou, Zhien, Xing, Yunzhi, Zhao, Yu, Liu, He, Tang, Jiayu, Chen, Qinghua, Hong, Lixin, Li, Wengang, Peng, Zhihai, Zhao, Bin, Johnson, Randy L, Liu, Pingguo, Hong, Wanjin, Chen, Lanfen, Zhou, Dawang

“…The loss of contact inhibition is a key step during carcinogenesis. The Hippo-Yes-associated protein (Hippo/YAP) pathway is an important regulator of cell…”
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miR-539 activates the SAPK/JNK signaling pathway to promote ferropotosis in colorectal cancer by directly targeting TIPE by Yang, Yan, Lin, Zeyang, Han, Zhaopu, Wu, Zhengxin, Hua, Jianyu, Zhong, Rui, Zhao, Ruidan, Ran, Honggang, Qu, Kaiyong, Huang, Hongfei, Tang, Huamei, Huang, Jiyi, Liu, Zhongchen, Hong, Xuehui, Peng, Zhihai, Zhuang, Guohong

“…Colorectal cancer (CRC) is a common tumor that harms human health with a high recurrence rate. It has been reported that the expression of microRNA-539…”
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KLF4-Mediated Negative Regulation of IFITM3 Expression Plays a Critical Role in Colon Cancer Pathogenesis by Li, Dawei, Peng, Zhihai, Tang, Huamei, Wei, Ping, Kong, Xiangyu, Yan, Dongwang, Huang, Fei, Li, Qiang, Le, Xiangdong, Li, Qi, Xie, Keping

“…IFITM3, an IFN-inducible gene, is overexpressed in human colorectal cancer. In this study, we sought to determine the clinical significance and underlying…”
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Musashi-2 potentiates colorectal cancer immune infiltration by regulating the post-translational modifications of HMGB1 to promote DCs maturation and migration by Meng, Xiaole, Na, Risi, Peng, Xiao, Li, Hui, Ouyang, Wanxin, Zhou, Wenting, You, Xuting, Li, Yuhuan, Pu, Xin, Zhang, Ke, Xia, Junjie, Wang, Jie, Tang, Huamei, Zhuang, Guohong, Peng, Zhihai

“…Post-translational modifications (PTMs) of the non-histone protein high-mobility group protein B1 (HMGB1) are involved in modulating inflammation and immune…”
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Msi-1 is a Predictor of Survival and a Novel Therapeutic Target in Colon Cancer by Li, Dawei, Peng, Xiao, Yan, Dongwang, Tang, Huamei, Huang, Fei, Yang, Yinxue, Peng, Zhihai

“…Background Musashi1 (Msi-1), a neural RNA-binding protein, plays an important role in regulating cell differentiation in precursor cells. Recently, aberrant…”
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