Search Results - "Zhi-Min Yuan"

Prognostic value of serum α-HBDH levels in patients with lung cancer by Yuan, Zhi-Min, Wang, Long-Hao, Chen, Cheng

“…The purpose of our study is to investigate the expression level and prognostic value of serum α-hydroxybutyrate dehydrogenase (α-HBDH) in lung cancer (LC)…”
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Functional interplay between p53 and Δ133p53 in adaptive stress response by Gong, Lu, Pan, Xiao, Abali, Gamze K., Little, John B., Yuan, Zhi-Min

“…Apart from its well-known prodeath activity, p53 is also implicated in promoting cell survival. How p53 can mediate such seemingly opposing effects is largely…”
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The Basally Expressed p53-Mediated Homeostatic Function by Nagpal, Isha, Yuan, Zhi-Min

“…Apart from mutations in the p53 gene, p53 functions can be alternatively compromised by a decrease in nuclear p53 protein levels or activities. In accordance,…”
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The p53 inhibitors MDM2/MDMX complex is required for control of p53 activity in vivo by Huang, Lei, Yan, Zheng, Liao, Xiaodong, Li, Yuan, Yang, Jie, Wang, Zhu-Gang, Zuo, Yong, Kawai, Hidehiko, Shadfan, Miriam, Ganapathy, Suthakar, Yuan, Zhi-Min

“…There are currently two distinct models proposed to explain why both MDM2 and MDMX are required in p53 control, with a key difference centered on whether these…”
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Crystal structure of catena-[(μ3-bromido)-(1H-1,2,4-triazol-1-yl)benzoato-κ1 N)copper(I)], C9H7BrCuN3O2 by Yuan, Zhi-Min, Xia, Yu-Pei

“…BrCuN , triclinic, 1̄ (no. 2),  = 3.8736(3) Å,  = 7.5238(7) Å,  = 18.1555(19) Å,  = 84.581(1)°,  =  ,  = 81.551(1)°,  = 520.96(8) Å ,  = 2, ) = 0.0344,…”
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Remnant Cholesterol and the Risk of Coronary Artery Calcium Progression: Insights From the CARDIA and MESA Study by Hao, Qing-Yun, Gao, Jing-Wei, Yuan, Zhi-Min, Gao, Ming, Wang, Jing-Feng, Schiele, François, Zhang, Shao-Ling, Liu, Pin-Ming

“…Background: Remnant cholesterol (RC) contributes to residual risk of atherosclerotic cardiovascular disease, but population-based evidence on the prospective…”
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ZBTB7A acts as a tumor suppressor through the transcriptional repression of glycolysis by Liu, Xue-Song, Haines, Jenna E, Mehanna, Elie K, Genet, Matthew D, Ben-Sahra, Issam, Asara, John M, Manning, Brendan D, Yuan, Zhi-Min

“…Elevated glycolysis is a common metabolic trait of cancer, but what drives such metabolic reprogramming remains incompletely clear. We report here a novel…”
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Can ultrasound irradiation be a therapeutic option for prostate cancer? by Maeshige, Noriaki, Kitagawa, Koichi, Yamasaki, Saya, Ishii, Aya, Shirakawa, Toshiro, Yang, Yong‐Ming, Sung, Shian‐Ying, Chen, Kuan‐Chou, Yuan, Zhi‐Min, Shigemura, Katsumi, Fujisawa, Masato

“…Background Focal therapies for prostate cancer (PC) can reduce adverse events and do not lead to androgen‐independent progression. Ultrasound could be used for…”
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High-intensity ultrasound irradiation promotes the release of extracellular vesicles from C2C12 myotubes by Maeshige, Noriaki, Langston, P. Kent, Yuan, Zhi-Min, Kondo, Hiroyo, Fujino, Hidemi

“…•High-intensity ultrasound strongly induced extracellular vesicle (EV) secretion from cultured myotubes.•High-intensity ultrasound did not change the viability…”
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A functional interplay between Δ133p53 and ΔNp63 in promoting glycolytic metabolism to fuel cancer cell proliferation by Gong, Lu, Pan, Xiao, Lim, Chuan-Bian, de Polo, Anna, Little, John B., Yuan, Zhi-Min

“…Although ΔNp63 is known to promote cancer cell proliferation, the underlying mechanism behind its oncogenic function remains elusive. We report here a…”
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Gas compensation-based abrasive flow processing method for complex titanium alloy surfaces by Zhang, Li, Wang, Jin-shun, Tan, Da-peng, Yuan, Zhi-min

“…To resolve the problems of uniformity and efficiency of soft abrasive flow (SAF) processing for complex titanium alloy surfaces, a gas compensation-based…”
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Uranium biosorption from aqueous solution onto Eichhornia crassipes by Yi, Zheng-ji, Yao, Jun, Chen, Hui-lun, Wang, Fei, Yuan, Zhi-min, Liu, Xing

“…Batch experiments were conducted to investigate the biosorption of U(VI) from aqueous solutions onto the nonliving biomass of an aquatic macrophyte Eichhornia…”
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Phosphorylation by aurora kinase A induces Mdm2-mediated destabilization and inhibition of p53 by Sen, Subrata, Katayama, Hiroshi, Sasai, Kaori, Kawai, Hidehiko, Yuan, Zhi-Min, Bondaruk, Jolanta, Suzuki, Fumio, Fujii, Satoshi, Arlinghaus, Ralph B, Czerniak, Bogdan A

“…Aurora kinase A (also called STK15 and BTAK) is overexpressed in many human cancers. Ectopic overexpression of aurora kinase A in mammalian cells induces…”
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CRISPR‐Cas9 systems: versatile cancer modelling platforms and promising therapeutic strategies by Wen, Wan‐Shun, Yuan, Zhi‐Min, Ma, Shi‐Jie, Xu, Jiang, Yuan, Dong‐Tang

“…The RNA‐guided nuclease CRISPR‐Cas9 (clustered regularly interspaced short palindromic repeats‐CRISPR associated nuclease 9) and its variants such as nickase…”
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Noise Mechanism of TDMR Readers at System Level by Zhi-Min Yuan, Chun Lian Ong, Zhejie Liu, Shiming Ang, Santoso, Budi

“…In perpendicular magnetic recording system, the jitter noise is the dominant noise from the medium. The jitter noise is proportional to the cross-track…”
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Skeletal myotube-derived extracellular vesicles enhance itaconate production and attenuate inflammatory responses of macrophages by Yamaguchi, Atomu, Maeshige, Noriaki, Yan, Jiawei, Ma, Xiaoqi, Uemura, Mikiko, Matsuda, Mami, Nishimura, Yuya, Hasunuma, Tomohisa, Kondo, Hiroyo, Fujino, Hidemi, Yuan, Zhi-Min

“…Macrophages play an important role in the innate immunity. While macrophage inflammation is necessary for biological defense, it must be appropriately…”
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Musashi1 Impacts Radio-Resistance in Glioblastoma by Controlling DNA-Protein Kinase Catalytic Subunit by de Araujo, Patricia Rosa, Gorthi, Aparna, da Silva, Acarizia E., Tonapi, Sonal S., Vo, Dat T., Burns, Suzanne C., Qiao, Mei, Uren, Philip J., Yuan, Zhi-Min, Bishop, Alexander J.R., Penalva, Luiz O.F.

“…The conserved RNA-binding protein Musashi1 (MSI1) has been characterized as a stem cell marker, controlling the balance between self-renewal and…”
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AXL receptor signalling suppresses p53 in melanoma through stabilization of the MDMX-MDM2 complex by de Polo, Anna, Luo, Zhongling, Gerarduzzi, Casimiro, Chen, Xiang, Little, John B, Yuan, Zhi-Min

“…Deregulation of the tyrosine kinase signalling is often associated with tumour progression and drug resistance, but its underlying mechanisms are only partly…”
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RING domain-mediated interaction is a requirement for MDM2's E3 ligase activity by KAWAI, Hidehiko, LOPEZ-PAJARES, Vanessa, KIM, Mihee M, WIEDERSCHAIN, Dmitri, YUAN, Zhi-Min

“…The RING domain of MDM2 that is essential for its E3 ligase activity mediates binding to itself and its structural homologue MDMX. Whereas it has been reported…”
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p53 Protects Cells from Death at the Heatstroke Threshold Temperature by Gong, Lu, Zhang, Qinghe, Pan, Xiao, Chen, Shuming, Yang, Lina, Liu, Bin, Yang, Weijun, Yu, Luyang, Xiao, Zhi-Xiong, Feng, Xin-Hua, Wang, Haihe, Yuan, Zhi-Min, Peng, Jinrong, Tan, Wei-Qiang, Chen, Jun

“…When the core body temperature is higher than 40°C, life is threatened due to heatstroke. Tumor repressor p53 is required for heat-induced apoptosis at…”
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