Search Results - "Zhi, Defu"

Targeting strategies for superparamagnetic iron oxide nanoparticles in cancer therapy by Zhi, Defu, Yang, Ting, Yang, Jian, Fu, Shuang, Zhang, Shubiao

“…Among various nanoparticles, superparamagnetic iron oxide nanoparticles (SPIONs) have been increasingly studied for their excellent superparamagnetism,…”
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The Headgroup Evolution of Cationic Lipids for Gene Delivery by Zhi, Defu, Zhang, Shubiao, Cui, Shaohui, Zhao, Yinan, Wang, Yinhuan, Zhao, Defeng

“…Cationic lipids are one of the most widely used nonviral vectors for gene delivery and are especially attractive because they can be easily synthesized and…”
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Lipid-based vectors for siRNA delivery by Zhang, Shubiao, Zhi, Defu, Huang, Leaf

“…siRNA therapeutics has developed rapidly and already there are clinical trials ongoing or planned; however, the delivery of siRNA into cells, tissues or organs…”
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Co-delivery of paclitaxel and anti-VEGF siRNA by tripeptide lipid nanoparticle to enhance the anti-tumor activity for lung cancer therapy by Zhang, Chuanmin, Zhao, Yinan, Zhang, Enxia, Jiang, Meilin, Zhi, Defu, Chen, Huiying, Cui, Shaohui, Zhen, Yuhong, Cui, Jingnan, Zhang, Shubiao

“…The combination of chemotherapeutic drug paclitaxel (PTX) and VEGF siRNA could inhibit cancer development with synergistic efficacy. However, efficient and…”
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Dual functionalized hyaluronic acid micelles loading paclitaxel for the therapy of breast cancer by Liu, Zhanbiao, Chen, Xuejun, Jin, Qian, Li, Min, Zhu, Siqing, Zhang, Yi, Zhi, Defu, Zhao, Yinan, Li, Liqin, Zhang, Shubiao

“…Although many carriers for the delivery of chemotherapeutic drugs have been investigated, the disadvantages of passive targeting and uncontrolled drug release…”
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Interaction kinetics of peptide lipids-mediated gene delivery by Zhao, Yinan, Zhao, Tianyi, Du, Yanyan, Cao, Yingnan, Xuan, Yang, Chen, Huiying, Zhi, Defu, Guo, Shutao, Zhong, Fangli, Zhang, Shubiao

“…During the course of gene transfection, the interaction kinetics between liposomes and DNA is speculated to play very important role for blood stability,…”
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Transmembrane routes of cationic liposome-mediated gene delivery using human throat epidermis cancer cells by Cui, Shaohui, Wang, Bing, Zhao, Yinan, Chen, Huiying, Ding, Huiqin, Zhi, Defu, Zhang, Shubiao

“…For studying the mechanism of cationic liposome-mediated transmembrane routes for gene delivery, various inhibitors of endocytosis were used to treat human…”
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Synthesis and biological activity of carbamate-linked cationic lipids for gene delivery in vitro by Zhi, Defu, Zhang, Shubiao, Qureshi, Farooq, Zhao, Yinan, Cui, Shaohui, Wang, Bing, Chen, Huiying, Wang, Yinhuan, Zhao, Defeng

“…We have introduced a convenient synthesis method for carbamate-linked cationic lipids, which exhibit relatively high transfection efficiency in Hela cells. We…”
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The biological routes of gene delivery mediated by lipid-based non-viral vectors by Duan, Yan, Zhang, Shubiao, Wang, Bing, Yang, Baoling, Zhi, Defu

“…Cationic lipid/DNA complexes (lipoplexes) represent an attractive alternative to viral vectors for cell transfection in vitro and in vivo but still suffer from…”
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Photothermal therapy by Zhi, Defu, Yang, Ting, O'Hagan, Justin, Zhang, Shubiao, Donnelly, Ryan F.

“…Microneedles (MNs), as an effective minimally invasive delivery route, when used to puncture the skin, can bypass the skin’s stratum corneum (SC) to enter the…”
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Microneedles for gene and drug delivery in skin cancer therapy by Zhi, Defu, Yang, Ting, Zhang, Tingyu, Yang, Mei, Zhang, Shubiao, Donnelly, Ryan F.

“…The success of skin cancer treatment is severely limited in the route of administration because most genes and drugs cannot break through the excellent stratum…”
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A review on cationic lipids with different linkers for gene delivery by Zhi, Defu, Bai, Yuchao, Yang, Jian, Cui, Shaohui, Zhao, Yinan, Chen, Huiying, Zhang, Shubiao

“…Cationic lipids have become known as one of the most versatile tools for the delivery of DNA, RNA and many other therapeutic molecules, and are especially…”
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Batch adsorption kinetic and thermodynamic studies of flavonoids from Dracocephalum Moldavia via flow injection online measurement by Dolkun, Almire, Muhammad, Turghun, Gao, Junxia, Chen, Yuanyuan, Zhang, Yan, Zhi, Defu, Zhang, Shubiao

“…[Display omitted] •An FIA method was developed for flavonoid determination during batch adsorption.•The method enables rapid, high-throughput, online and…”
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Co-delivery of paclitaxel and survivin siRNA with cationic liposome for lung cancer therapy by Zhang, Chuanmin, Zhang, Shubiao, Zhi, Defu, Zhao, Yinan, Cui, Shaohui, Cui, Jingnan

“…[Display omitted] This work designed a new delivery system (L-PTX-PSur), which could efficiently co-deliver paclitaxel (PTX) and survivin siRNA (Sur) to…”
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Apoptosis induced by cationic liposome based on the mitochondrial signaling pathway in vitro by Du, Sang, Wang, Yueying, Li, Min, Zhao, Yinan, Zhi, Defu, Cui, Shaohui, Zhang, Shubiao

“…Liposomes have been extensively applied in gene and drug delivery. It is indicated in many studies that cationic lipids possess a certain degree of…”
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Transfection Efficiency of Cationic Lipids with Different Hydrophobic Domains in Gene Delivery by Zhi, DeFu, Zhang, ShuBiao, Wang, Bing, Zhao, YiNan, Yang, BaoLing, Yu, ShiJun

“…The structure of cationic lipids is a major factor for their transfection activity. A cationic lipid generally contains four functional domains: a hydrophilic…”
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Correlation of the cytotoxic effects of cationic lipids with their headgroups by Cui, Shaohui, Wang, Yueying, Gong, Yan, Lin, Xiao, Zhao, Yinan, Zhi, Defu, Zhou, Quan, Zhang, Shubiao

“…As effective non-viral vectors of gene therapy, cationic lipids still have the problem of toxicity, which has become one of the main bottlenecks for their…”
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Structure–activity relationships of pH-responsive and ionizable lipids for gene delivery by Zou, Yu, Zhou, Quan, Zhao, Yinan, Zhi, Defu, Chen, Huiying, Wang, Rui, Ju, Benzhi, Zhang, Shubiao

“…[Display omitted] •Four pH-responsive and ionizable lipids were synthesized.•Liposomes showed remarkable siRNA condensation and pH-responsiveness.•EDM liposome…”
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Integrin αvβ3-targeted liposomal drug delivery system for enhanced lung cancer therapy by Fu, Shuang, Zhao, Yinan, Sun, Jiao, Yang, Ting, Zhi, Defu, Zhang, Enxia, Zhong, Fangli, Zhen, Yuhong, Zhang, Shufen, Zhang, Shubiao

“…[Display omitted] •RGD peptide-based lipids were synthesized to develop modified liposomes.•The modified liposomes improved the cellular uptake and…”
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Stimuli-Responsive Polysaccharide Enveloped Liposome for Targeting and Penetrating Delivery of survivin-shRNA into Breast Tumor by Chen, Huiying, Fan, Xuefeng, Zhao, Yinan, Zhi, Defu, Cui, Shaohui, Zhang, Enxia, Lan, Haoming, Du, Jianjun, Zhang, Zhen, Zhang, Shubiao, Zhen, Yuhong

“…Silencing the inhibitor of apoptosis (IAP) by RNAi is a promising method for tumor therapy. One of the major challenges lies in how to sequentially overcome…”
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