Search Results - "Zheremyan, Elina A"
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Autoimmunity-Associated SNP rs3024505 Disrupts STAT3 Binding in B Cells, Leading to IL10 Dysregulation
Published in International journal of molecular sciences (23-09-2024)“…Interleukin 10 (IL10) is a major anti-inflammatory cytokine that acts as a master regulator of the immune response. A single nucleotide polymorphism…”
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Breg-Mediated Immunoregulation in the Skin
Published in International journal of molecular sciences (01-01-2024)“…Wound healing is a complex process involving a coordinated series of events aimed at restoring tissue integrity and function. Regulatory B cells (Bregs) are a…”
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rs71327024 Associated with COVID-19 Hospitalization Reduces CXCR6 Promoter Activity in Human CD4+ T Cells via Disruption of c-Myb Binding
Published in International journal of molecular sciences (07-09-2023)“…Single-nucleotide polymorphism rs71327024 located in the human 3p21.31 locus has been associated with an elevated risk of hospitalization upon SARS-CoV-2…”
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Differentially activated B cells develop regulatory phenotype and show varying immunosuppressive features: a comparative study
Published in Frontiers in immunology (05-09-2023)“…Regulatory B lymphocytes (Bregs) are B cells with well-pronounced immunosuppressive properties, allowing them to suppress the activity of effector cells. A…”
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Methods for Functional Characterization of Genetic Polymorphisms of Non-Coding Regulatory Regions of the Human Genome
Published in Biochemistry (Moscow) (01-06-2024)“…Currently, numerous associations between genetic polymorphisms and various diseases have been characterized through the Genome-Wide Association Studies…”
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Interaction Between Adipocytes and B Lymphocytes in Human Metabolic Diseases
Published in Biochemistry (Moscow) (01-02-2023)“…Diseases associated with the disorders of carbohydrate and lipid metabolism are widespread in the modern world. Interaction between the cells of adipose tissue…”
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Novel Potential Mechanisms of Regulatory B Cell-Mediated Immunosuppression
Published in Biochemistry (Moscow) (2023)“…B lymphocytes play an important role in the regulation of immune response in both normal and pathological conditions. Traditionally, the main functions of B…”
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rs71327024 Associated with COVID-19 Hospitalization Reduces ICXCR6/I Promoter Activity in Human CD4[sup.+] T Cells via Disruption of c-Myb Binding
Published in International journal of molecular sciences (01-09-2023)“…Single-nucleotide polymorphism rs71327024 located in the human 3p21.31 locus has been associated with an elevated risk of hospitalization upon SARS-CoV-2…”
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Journal Article