Search Results - "Zherdev, V P"

Preclinical Pharmacokinetic and Pharmacodynamic Studies of Pharmaceutical Compositions of the Dipeptide Anxiolytic GB-115 by Zherdev, V. P., Boiko, S. S., Konstantinopol’skii, M. A., Raskin, S. Yu, Alekseev, K. V., Gudasheva, T. A., Mart’yanov, V. A., Kolik, L. G.

“…Four pharmaceutical compositions for oral use that contained the dipeptide anxiolytic GB-115 as the active ingredient underwent preclinical trials in male…”
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Regional and Subcellular Localization of Cycloprolylglycine in Rat Brain by Boiko, S. S, Gudasheva, T. A, Vichuzhanin, M. V, Zherdev, V. P, Seredenin, S. B

“…HPLC analysis showed that endogenous cyclopeptide cycloprolylglycine exhibiting mnemotropic and anxiolytic properties is nonuniformly distributed between brain…”
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Preclinical Pharmacokinetics of GZK-111, a Dipeptide with Neuroprotective Activity by Litvin, A. A., Kolyvanov, G. B., Bochkov, P. O., Shevchenko, R. V., Podol’ko, A. L., Kolyasnikova, K. N., Zherdev, V. P.

“…We studied the pharmacokinetics of GZK-111 (N-phenylacetyl-glycyl-L-proline ethyl ether), a compound with neuroprotective activity, and its metabolite CPG…”
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Thermodynamics and Structure of Micelles in Aqueous Solutions of Sodium Decyl Sulfate in the Region of the Third Critical Micelle Concentration by Kuznetsov, V. S., Zherdev, V. P., Badelin, V. G., Zherdeva, V. V.

“…Using data on heat capacity of sodium decyl sulfate solutions near the third critical micelle concentration, obtained earlier via high-precision scanning…”
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Properties of Micellar Solutions of Sodium Decyl Sulfate at Relatively High Concentrations by Kuznetsov, V. S., Badelin, V. G., Tyunina, E. Yu, Zherdev, V. P.

“…Heat capacities of aqueous solutions of anionic surfactant sodium decyl sulfate in the 0.28–0.42 mol kg −1 range of molar concentrations and the 278–363 K…”
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Metabolism of a New Dipeptide Neuroprotector in Rats by Kolyvanov, G. B., Bochkov, P. O., Litvin, A. A., Shevchenko, R. V., Podol’ko, A. L., Kravtsova, O. Yu, Kolyasnikova, K. N., Zherdev, V. P.

“…Metabolism of a new neuroprotector GZK-111 ( N -phenylacetylglycyl- L -proline ethyl ester) in rat blood plasma was studied by HPLC-mass spectrometry. Four…”
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Comparative Analysis of Tissue Availability for Afobazole and Compound M-11 by Viglinskaya, A. O, Bastrygin, D. V, Kolyvanov, G. B, Litvin, A. A, Zherdev, V. P, Mozhaeva, T. Ya

“…Comparative analysis of pharmacokinetic parameters of afobazole and its main metabolite M-11 after single intraperitoneal injections of their solutions (25…”
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Comparative Preclinical Pharmacokinetics and Bioavailability of Antidepressant GSB-106 Tablet Form by Kolyvanov, G. B., Zherdev, V. P., Gribakina, O. G., Bochkov, P. O., Shevchenko, R. V., Litvin, A. A., Blynskaya, E. V., Bueva, V. V.

“…Pharmacokinetics and relative bioavailability of antidepressant GSB-106 (hexamethylendiamide bis -( N -monosuccinyl- L -seryl- L -lysine) were determined in…”
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Thermodynamics of the surfaces of nonionic spherical micelles with relatively large extensions of the interfacial layer by Kuznetsov, V. S., Blinov, A. P., Zherdev, V. P.

“…The structural properties of nonionic spherical micelles with relatively large extensions of the interfacial layer are investigated, and the size dependences…”
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Excretion of afobazole and its metabolites with urine and feces in rats by Viglinskaya, A. O, Kolyvanov, G. B, Litvin, A. A, Zherdev, V. P, Seredenin, S. B

“…The amount of afobazole and identified metabolites was measured in the urine and feces of rats after intraperitoneal and peroral administration of the drug in…”
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Metabolism of a Novel Anxiolytic GML-1 in Rats by Novitskii, A. A., Bochkov, P. O., Shevchenko, R. V., Gribakina, O. G., Litvin, A. A., Kolyvanov, G. B., Zherdev, V. P.

“…Metabolism of a novel anxiolytic GML-1 ( N -benzyl- N -methyl-1-phenylpyrrolo[1,2-a]pirazin-3-carboxamide) in rat blood plasma was studied by HPLC-mass…”
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Comparative Pharmacokinetics and Relative Bioavailability of a New Anxiolytic GML-1 in Tablet Form by Novitskiy, A. A., Litvin, A. A., Shevchenko, R. V., Bochkov, P. O., Gribakina, O. G., Kolyvanov, G. B., Zherdev, V. P., Alekseev, K. V., Blynskaya, E. V., Yudina, D. V., Smirnov, V. V.

“…An open, single, crossover, pharmacokinetic study of GML-1 (dose 50 mg/kg) in rabbits after its oral administration in tablets and alone as a substance is…”
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Quantification of Hexamethylenediamide Bis(N-Monosuccinyl-L-Seryl-L-Lysine) (GSB-106) in the Blood Plasma by HPLC–MS by Grybakina, O. G., Lopatina, N. B., Blynskaya, E. V., Bochkov, P. O., Shevchenko, R. V., Litvin, A. A., Kolyvanov, G. B., Zherdev, V. P., Kondakov, S. E.

“…The technique of the quantitative determination of GSB-106 in the blood plasma of rats is developed and validated. The analysis is performed by HPLC–MS. The…”
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Quantification of Hexamethylenediamide Bis(N-Monosuccinyl-L-Glutamyl-L-Lysine) in Blood Plasma by HPLC–MS by Litvin, A. A., Kolyvanov, G. K., Blynskaya, E. V., Grybakina, O. G., Bochkov, P. O., Shevchenko, R. V., Zherdev, V. P.

“…The quantitative determination of a new compound hexamethylenediamide bis( N -monosuccinyl-L-glutamyl-L-lysine) (GK-2) in rat blood plasma is developed and…”
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Development and Validation of the Quantification of GML-1 Compound (N-benzyl-N-methyl-1-phenylpyrrolo[1,2-A] pyrazine- 3-carbamide) in the Blood Plasma of Rats by HPLC–MS by Novitskiy, A. A., Bochkov, P. O., Litvin, A. A., Zherdev, V. P., Blynskaya, E. V.

“…The technique of quantitative determination of a new compound, possessing anxiolytic activity, GML-1 in the blood plasma of rats is developed and validated…”
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Dielectric permittivity in a dense layer of the hydration shell of an ion in a strong-electrolyte solution by Kuznetsov, V. S., Usol’tseva, N. V., Zherdev, V. P.

“…Based on the experimental data on the dielectric dispersion and the static dielectric permittivity of solutions of strong electrolytes, the effective value of…”
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Identification of a novel endogenous memory facilitating cyclic dipeptide cyclo-prolylglycine in rat brain by Gudasheva, T.A, Boyko, S.S, Akparov, V.Kh, Ostrovskaya, R.U, Skoldinov, S.P, Rozantsev, G.G, Voronina, T.A, Zherdev, V.P, Seredenin, S.B

“…Using high-performance liquid chromatography, gas-chromatography and chromato-mass spectrometry methods a novel endogenous cyclic dipeptide cyclo-prolylglycine…”
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Comparison of Pharmacokinetics and Relative Bioavailability of Tablets and Substance of New Dipeptide Neuroleptic Dilept by Shevchenko, R. V., Litvin, A. A., Kolyvanov, G. B., Zherdev, V. P., Smirnov, V. V.

“…We studied pharmacokinetics of dilept after single cross-administration of tablets and substance of dilept in a dose of 40 mg to rabbits. The following…”
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Comparative study of pharmacokinetics and enzymatic resistance of the neuroprotective mean GZK-111 and noopept in rats by S. S. Boyko, K. N. Koliasnikova, V. P. Zherdev

“…The article presents the results of studying the pharmacokinetics and enzymatic stability of a new pharmacologically active compound GZK-111–…”
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Pharmacokinetics of a potential antiepileptic drug GIZh-298 by G. B. Kolyvanov, A. A. Litvin, O. Yu. Kravtsova, O. G. Gribakina, V. P. Zherdev

“…GIZh-298 pharmacokinetics was studied in rats after different dosage regimens.The aim of this study was to study GIZh-298 pharmacokinetics after its multiple…”
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