Search Results - "Zheng, Zhaojing"

Rapid syntheses of N-fused heterocycles via acyl-transfer in heteroaryl ketones by Ye, Dan, Lu, Hong, He, Yi, Zheng, Zhaojing, Wu, Jinghao, Wei, Hao

“…The wide-ranging potencies of bioactive N -fused heterocycles inspire the development of synthetic transformations that simplify preparation of their complex,…”
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Anti-Obesity and Gut Microbiota Modulation Effect of Secoiridoid-Enriched Extract from Fraxinus mandshurica Seeds on High-Fat Diet-Fed Mice by Guo, Sen, Zhao, Haoan, Ma, Zhongxiao, Zhang, Shanshan, Li, Mingrou, Zheng, Zhaojing, Ren, Xiameng, Ho, Chi-Tang, Bai, Naisheng

“…Previously we conducted a phytochemical study on the seeds of and isolated nine secoiridoid compounds with adipocyte differentiation inhibitory activity and…”
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Nickel‐Catalyzed Directed Benzylation of Ortho C−H Bonds in Aromatic Amides through C−H/C−N Cleavage by Li, Jiawei, Zheng, Zhaojing, Xiao, Tiantian, Xu, Peng‐Fei, Wei, Hao

“…The cleavage of both sp2 C−H and C−N bonds by a nickel‐catalyzed reaction of aromatic amides containing an 8‐aminoquinoline moiety with benzyl ammonium salts…”
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A novel missense mutation of TNNI2 in a Chinese family cause distal arthrogryposis type 1 by Wang, Bo, Zheng, Zhaojing, Wang, Zhigang, Zhang, Xiaoqing, Yang, Haiou, Cai, Haiqing, Fu, Qihua

“…The distal arthrogryposis (DA) syndromes are a group of disorders characterized by congenital contractures of limbs. According to phenotypical characteristics,…”
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Screening for coding variants in FTO and SH2B1 genes in Chinese patients with obesity by Zheng, Zhaojing, Hong, Li, Huang, Xiaodong, Yang, Peirong, Li, Juan, Ding, Yu, Yao, Ru-En, Geng, Juan, Shen, Yongnian, Shen, Yiping, Fu, Qihua, Yu, Yongguo

“…To investigate potential functional variants in FTO and SH2B1 genes among Chinese children with obesity. Sanger sequencing of PCR products of all FTO and SH2B1…”
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Nitrogen atom insertion into arenols to access benzazepines by He, Yi, Wang, Juanjuan, Zhu, Tongtong, Zheng, Zhaojing, Wei, Hao

“…Advances in site-selective molecular editing have enabled structural modification on complex molecules. However, thus far, their applications have been…”
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Brønsted Acid‐Catalyzed Markovnikov Hydroarylation of Arylcyclobutene: A Route to gem‐Diaryl‐Substituted Cyclobutanes by Wang, Xiuhong, Sun, Zhening, Wang, Juanjuan, Zheng, Zhaojing, Lu, Hong, Wei, Hao

“…A regioselective Markovnikov hydroarylation of arylcyclobutene has been developed using Brønsted acid catalysis through a protonation/Friedel‐Crafts sequence…”
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A non-covalent binding strategy for the stabilization of fish collagen triple helices to promote its applications by Sun, Zhening, Ge, Yihao, Cai, Xinhui, Liu, Qian, Yang, Zhiwei, Chen, Xi, Zheng, Zhaojing

“…Collagen, with its most characteristic structural unit, the triple helix, has wide applications in pharmaceutical and cosmetic industries. However, the…”
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Molecular diagnostics for congenital heart disease: a narrative review of the current technologies and applications by Zu, Bailing, Zheng, Zhaojing, Fu, Qihua

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Three novel missense mutations in the filamin B gene are associated with isolated congenital talipes equinovarus by Yang, Haiou, Zheng, Zhaojing, Cai, Haiqing, Li, Huimin, Ye, Xingchen, Zhang, Xiaoqing, Wang, Zhigang, Fu, Qihua

“…Congenital talipes equinovarus (CTEV) is one of the most common musculoskeletal disorders. Genetic factors have been suggested to be an important contributor…”
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Chromosome microarray testing for patients with congenital heart defects reveals novel disease causing loci and high diagnostic yield by Geng, Juan, Picker, Jonathan, Zheng, Zhaojing, Zhang, Xiaoqing, Wang, Jian, Hisama, Fuki, Brown, David W, Mullen, Mary P, Harris, David, Stoler, Joan, Seman, Ann, Miller, David T, Fu, Qihua, Roberts, Amy E, Shen, Yiping

“…Congenital heart defects (CHD), as the most common congenital anomaly, have been reported to be frequently associated with pathogenic copy number variants…”
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Toll-like receptor 6 V327M polymorphism is associated with an increased risk of Klebsiella pneumoniae infection by Yang, Haiou, Zhang, Xiaoqing, Geng, Juan, Zheng, Zhaojing, Fu, Qihua

“…Klebsiella pneumoniae is a common cause of nosocomial pneumonia, especially in children. Toll-like receptors plays an important role in defense against this…”
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A novel GJA1 mutation identified by whole exome sequencing in a Chinese family with autosomal dominant syndactyly by You, Guolin, Cai, Haiqing, Jiang, Limin, Zheng, Zhaojing, Wang, Bo, Fu, Qihua, Wang, Jing

“…Syndactyly is one of the most common hereditary limb malformations characterized by fusion of adjacent fingers and/or toes. The current classification scheme…”
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Rare Copy Number Variations Might Not be Involved in the Molecular Pathogenesis of PA–IVS in an Unselected Chinese Cohort by He, Xiaomin, Zhang, Xiaoqing, Jing, Hui, Zhang, Xiaoyang, Gao, Manchen, Chen, Huiwen, Geng, Juan, Zheng, Zhaojing, Fu, Qihua, Zhu, Zhongqun, Zheng, Jinghao

“…Congenital heart defect (CHD) is one of the most common birth defects in China, while pulmonary atresia with intact ventricular septum (PA–IVS) is the…”
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A New Subtype of Multiple Synostoses Syndrome Is Caused by a Mutation in GDF6 That Decreases Its Sensitivity to Noggin and Enhances Its Potency as a BMP Signal by Wang, Jian, Yu, Tingting, Wang, Zhigang, Ohte, Satoshi, Yao, Ru‐en, Zheng, Zhaojing, Geng, Juan, Cai, Haiqing, Ge, Yihua, Li, Yuchan, Xu, Yunlan, Zhang, Qinghua, Gusella, James F, Fu, Qihua, Pregizer, Steven, Rosen, Vicki, Shen, Yiping

“…ABSTRACT Growth and differentiation factors (GDFs) are secreted signaling molecules within the BMP family that have critical roles in joint morphogenesis…”
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Molecular defects identified by whole exome sequencing in a child with Fanconi anemia by Zheng, Zhaojing, Geng, Juan, Yao, Ru-en, Li, Caihua, Ying, Daming, Shen, Yongnian, Ying, Lei, Yu, Yongguo, Fu, Qihua

“…Fanconi anemia is a rare genetic disease characterized by bone marrow failure, multiple congenital malformations, and an increased susceptibility to…”
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A unique combination of 17pter trisomy and 21qter monosomy in a boy with developmental delay, severe intellectual disability, growth retardation and dysmorphisms by Zheng, Zhaojing, Yao, Ru-en, Geng, Juan, Jin, Xingming, Shen, Yongnian, Ying, Daming, Fu, Qihua, Yu, Yongguo

“…Microduplication at 17p13.3 and microdeletion at 21q22 are both rare chromosomal aberrations. The presence of both genomic imbalances in one patient has not…”
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Identification of LDLR mutations in two Chinese pedigrees with familial hypercholesterolemia by Yao, Ru-En, Wang, Jian, Geng, Juan, Zheng, Zhaojing, Yu, Tingting, Yu, Yongguo, Fu, Qihua

“…Familial hypercholesterolemia (FH) is an autosomal dominant, inherited disease (OMIM 143890) characterized by elevated serum cholesterol bound to low-density…”
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Elevated NKT cell levels in adults with severe chronic immune thrombocytopenia by XU, RUILONG, ZHENG, ZHAOJING, MA, YONGJUN, HU, YINGPING, ZHUANG, SHUNHONG, WEI, BIN, LU, JIANXING

“…The aim of this study was to investigate the frequency of circulating natural killer T (NKT) cells and regulatory T cells (Tregs), as well as serum cytokine…”
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Screening for Coding Variants in FTO and SH2B1 Genes in Chinese Patients with Obesity. e67039 by Zheng, Zhaojing, Hong, Li, Huang, Xiaodong, Yang, Peirong, Li, Juan, Ding, Yu, Yao, Ru-en, Geng, Juan, Shen, Yongnian, Shen, Yiping

“…Objective To investigate potential functional variants in FTO and SH2B1 genes among Chinese children with obesity. Methods Sanger sequencing of PCR products of…”
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