Search Results - "Zheng, Yufang"

Embryonic Lethal Phenotyping to Identify Candidate Genes Related with Birth Defects by Yan, Bing, Gong, Baoming, Zheng, Yufang, Sun, Lei, Wu, Xiaohui

“…Congenital birth defects contribute significantly to preterm birth, stillbirth, perinatal death, infant mortality, and adult disability. As a first step to…”
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WDR34 mutation from anencephaly patients impaired both SHH and PCP signaling pathways by Yin, Hailing, Peng, Rui, Chen, Zhongzhong, Wang, Hongyan, Zhang, Ting, Zheng, Yufang

“…Neural tube defects (NTDs) are debilitating human congenital abnormalities due to failure of neural tube closure. Sonic Hedgehog (SHH) signaling is required…”
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SRPS associated protein WDR60 regulates the multipolar-to-bipolar transition of migrating neurons during cortical development by Li, Cui, Zheng, Yu, Zheng, Yufang, Xu, Zhiheng

“…Mutations of WD40 repeat domain 60 ( WDR60 ) have been identified in short-rib polydactyly syndromes (SRPS I–V), a group of lethal congenital disorders…”
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Molecular Species of the Alcohol Biomarker Phosphatidylethanol in Human Blood Measured by LC-MS by Helander, Anders, Zheng, Yufang

“…The alcohol biomarker phosphatidylethanol (PEth) comprises a group of ethanol-derived phospholipids formed from phosphatidylcholine by phospholipase D. The…”
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Monitoring of the Alcohol Biomarkers PEth, CDT and EtG/EtS in an Outpatient Treatment Setting by HELANDER, Anders, PETER, Oszkar, YUFANG ZHENG

“…To compare the sensitivity of whole blood phosphatidylethanol (PEth) with serum carbohydrate-deficient transferrin (CDT) as biomarkers of current regular…”
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High glucose causes developmental abnormalities in neuroepithelial cysts with actin and HK1 distribution changes by Peng, Sisi, Wu, Yu, Zheng, Yufang

“…It has been reported that the offspring of diabetic pregnant women have an increased risk for neural tube defects. Previous studies in animal models suggested…”
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Author Correction: Threshold for neural tube defect risk by accumulated singleton loss-of-function variants by Chen, Zhongzhong, Lei, Yunping, Zheng, Yufang, Aguiar-Pulido, Vanessa, Ross, M. Elizabeth, Peng, Rui, Jin, Li, Zhang, Ting, Finnell, Richard H., Wang, Hongyan

“…A Correction to this paper has been published: https://doi.org/10.1038/s41422-021-00475-z…”
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Deficiency of Wdr60 and Wdr34 cause distinct neural tube malformation phenotypes in early embryos by Yan, Lu, Yin, Hailing, Mi, Yiwei, Wu, Yu, Zheng, Yufang

“…Cilia are specialized organelles that extend from plasma membrane, functioning as antennas for signal transduction and are involved in embryonic morphogenesis…”
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Loss of Tctn3 causes neuronal apoptosis and neural tube defects in mice by Wang, Bin, Zhang, Yingying, Dong, Hongli, Gong, Siyi, Wei, Bin, Luo, Man, Wang, Hongyan, Wu, Xiaohui, Liu, Wei, Xu, Xingshun, Zheng, Yufang, Sun, Miao

“…Tctn3 belongs to the Tectonic (Tctn) family and is a single-pass membrane protein localized at the transition zone of primary cilia as an important component…”
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Genetic analysis of Wnt/PCP genes in neural tube defects by Chen, Zhongzhong, Lei, Yunping, Cao, Xuanye, Zheng, Yufang, Wang, Fang, Bao, Yihua, Peng, Rui, Finnell, Richard H, Zhang, Ting, Wang, Hongyan

“…Mouse homozygous mutants in Wnt/planar cell polarity (PCP) pathway genes have been shown to cause neural tube defects (NTDs) through the disruption of normal…”
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Parental folate deficiency induces birth defects in mice accompanied with increased de novo mutations by Zhao, Ying, Chen, Duoyuan, Tang, Jianping, Zheng, Yufang, Qi, Ji, Wang, Hongyan

“…Dietary folate deficiency (FD) is associated with the occurrence of birth defects. However, the mechanisms underlying this association remain elusive. In…”
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Prevalence of anemia among adults with newly diagnosed HIV/AIDS in China by Shen, Yinzhong, Wang, Zhenyan, Lu, Hongzhou, Wang, Jiangrong, Chen, Jun, Liu, Li, Zhang, Renfang, Zheng, Yufang

“…The prevalence of anemia among antiretroviral-naïve HIV-infected patients in China has not been well characterized. We conducted a cross-sectional study to…”
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Diagnosis of liver cancer using HPLC-based metabonomics avoiding false-positive result from hepatitis and hepatocirrhosis diseases by Yang, Jun, Xu, Guowang, Zheng, Yufang, Kong, Hongwei, Pang, Tao, Lv, Shen, Yang, Qing

“…Metabonomics, the study of metabolites and their roles in various disease states, is a novel methodology arising from the post-genomics era. This methodology…”
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A promoter variant in ZNF804A decreasing its expression increases the risk of autism spectrum disorder in the Han Chinese population by Zhang, Linna, Qin, Yue, Gong, Xiaohong, Peng, Rui, Cai, Chunquan, Zheng, Yufang, Du, Yasong, Wang, Hongyan

“…Synaptic pathology may be one of the cellular substrates underlying autism spectrum disorder (ASD). ZNF804A is a transcription factor that can affect or…”
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Identification of functional mutations in GATA4 in patients with congenital heart disease by Wang, Erli, Sun, Shuna, Qiao, Bin, Duan, Wenyuan, Huang, Guoying, An, Yu, Xu, Shuhua, Zheng, Yufang, Su, Zhixi, Gu, Xun, Jin, Li, Wang, Hongyan

“…Congenital heart disease (CHD) is one of the most prevalent developmental anomalies and the leading cause of noninfectious morbidity and mortality in newborns…”
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Interferon-gamma release assays for the diagnosis of active tuberculosis in HIV-infected patients: a systematic review and meta-analysis by Chen, Jun, Zhang, Renfang, Wang, Jiangrong, Liu, Li, Zheng, Yufang, Shen, Yinzhong, Qi, Tangkai, Lu, Hongzhou

“…Interferon-gamma release assays (IGRAs) have provided a new method for the diagnosis of Mycobacterium tuberculosis infection. However, the role of IGRAs for…”
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Evidence for OTUD-6B participation in B lymphocytes cell cycle after cytokine stimulation by Xu, Zhongping, Zheng, Yufang, Zhu, Yufei, Kong, Xiangyin, Hu, Landian

“…Deubiquitinating enzymes (DUBs) are important regulators of cell proliferation. Here we identified a functional deubiquitinating enzyme, ovarian tumor…”
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Ablation of Vacuole Protein Sorting 18 (Vps18) Gene Leads to Neurodegeneration and Impaired Neuronal Migration by Disrupting Multiple Vesicle Transport Pathways to Lysosomes by Peng, Chao, Ye, Jian, Yan, Shunfei, Kong, Shanshan, Shen, Ye, Li, Chenyu, Li, Qinyu, Zheng, Yufang, Deng, Kejing, Xu, Tian, Tao, Wufan

“…Intracellular vesicle transport pathways are critical for neuronal survival and central nervous system development. The Vps-C complex regulates multiple…”
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Analysis and prediction of translation rate based on sequence and functional features of the mRNA by Huang, Tao, Wan, Sibao, Xu, Zhongping, Zheng, Yufang, Feng, Kai-Yan, Li, Hai-Peng, Kong, Xiangyin, Cai, Yu-Dong

“…Protein concentrations depend not only on the mRNA level, but also on the translation rate and the degradation rate. Prediction of mRNA's translation rate…”
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Combination of β-elimination and liquid chromatography/quadrupole time-of-flight mass spectrometry for the determination of O-glycosylation sites by Zheng, Yufang, Guo, Zhihong, Cai, Zongwei

“…Determination of O-glycosylation sites in glycopeptides was developed by using two model compounds designed from mucin2 tandem repeat motif and erythropoietin…”
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