Search Results - "Zheng, Yonglan"

Whole-genome analysis of Nigerian patients with breast cancer reveals ethnic-driven somatic evolution and distinct genomic subtypes by Ansari-Pour, Naser, Zheng, Yonglan, Yoshimatsu, Toshio F., Sanni, Ayodele, Ajani, Mustapha, Reynier, Jean-Baptiste, Tapinos, Avraam, Pitt, Jason J., Dentro, Stefan, Woodard, Anna, Rajagopal, Padma Sheila, Fitzgerald, Dominic, Gruber, Andreas J., Odetunde, Abayomi, Popoola, Abiodun, Falusi, Adeyinka G., Babalola, Chinedum Peace, Ogundiran, Temidayo, Ibrahim, Nasiru, Barretina, Jordi, Van Loo, Peter, Chen, Mengjie, White, Kevin P., Ojengbede, Oladosu, Obafunwa, John, Huo, Dezheng, Wedge, David C., Olopade, Olufunmilayo I.

“…Black women across the African diaspora experience more aggressive breast cancer with higher mortality rates than white women of European ancestry. Although…”
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Detection of germline variants in Brazilian breast cancer patients using multigene panel testing by Guindalini, Rodrigo Santa Cruz, Viana, Danilo Vilela, Kitajima, João Paulo Fumio Whitaker, Rocha, Vinícius Marques, López, Rossana Verónica Mendoza, Zheng, Yonglan, Freitas, Érika, Monteiro, Fabiola Paoli Mendes, Valim, André, Schlesinger, David, Kok, Fernando, Olopade, Olufunmilayo I., Folgueira, Maria Aparecida Azevedo Koike

“…Genetic diversity of germline variants in breast cancer (BC) predisposition genes is unexplored in miscegenated populations, such those living in Latin…”
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Whole-exome and targeted gene sequencing of gallbladder carcinoma identifies recurrent mutations in the ErbB pathway by Li, Maolan, Zhang, Zhou, Li, Xiaoguang, Ye, Junyi, Wu, Xiangsong, Tan, Zhujun, Liu, Chang, Shen, Baiyong, Wang, Xu-An, Wu, Wenguang, Zhou, Daizhan, Zhang, Di, Wang, Ting, Liu, Bingya, Qu, Kai, Ding, Qichen, Weng, Hao, Ding, Qian, Mu, Jiasheng, Shu, Yijun, Bao, Runfa, Cao, Yang, Chen, Peizhan, Liu, Tianyu, Jiang, Lin, Hu, Yunping, Dong, Ping, Gu, Jun, Lu, Wei, Shi, Weibin, Lu, Jianhua, Gong, Wei, Tang, Zhaohui, Zhang, Yong, Wang, Xuefeng, Chin, Y Eugene, Weng, Xiaoling, Zhang, Hong, Tang, Wei, Zheng, Yonglan, He, Lin, Wang, Hui, Liu, Yun, Liu, Yingbin

“…Yingbin Liu, Yun Liu, Hui Wang and colleagues perform whole-exome and targeted gene sequencing of gallbladder carcinoma. They identify recurrent somatic…”
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Common variants on chromosome 6p22.1 are associated with schizophrenia by Gejman, Pablo V, Shi, Jianxin, Levinson, Douglas F, Duan, Jubao, Sanders, Alan R, Zheng, Yonglan, Pe'er, Itsik, Dudbridge, Frank, Holmans, Peter A, Whittemore, Alice S, Mowry, Bryan J, Olincy, Ann, Amin, Farooq, Cloninger, C. Robert, Silverman, Jeremy M, Buccola, Nancy G, Byerley, William F, Black, Donald W, Crowe, Raymond R, Oksenberg, Jorge R, Mirel, Daniel B, Kendler, Kenneth S, Freedman, Robert

“…Schizophrenia, a devastating psychiatric disorder, has a prevalence of 0.5-1%, with high heritability (80-85%) and complex transmission. Recent studies…”
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Racial disparities in survival outcomes among breast cancer patients by molecular subtypes by Zhao, Fangyuan, Copley, Brenda, Niu, Qun, Liu, Fang, Johnson, Julie A., Sutton, Thomas, Khramtsova, Galina, Sveen, Elisabeth, Yoshimatsu, Toshio F., Zheng, Yonglan, Ibraheem, Abiola, Jaskowiak, Nora, Nanda, Rita, Fleming, Gini F., Olopade, Olufunmilayo I., Huo, Dezheng

“…Purpose Differences in tumor biology, genomic architecture, and health care delivery patterns contribute to the breast cancer mortality gap between White and…”
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Subtype-specific expression of MELK is partly due to copy number alterations in breast cancer by Hardeman, Ashley A, Han, Yoo Jane, Grushko, Tatyana A, Mueller, Jeffrey, Gomez, Maria J, Zheng, Yonglan, Olopade, Olufunmilayo I

“…Maternal embryonic leucine-zipper kinase (MELK) regulates cell cycle progression and is highly expressed in many cancers. The molecular mechanism of MELK…”
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Population-dependent Intron Retention and DNA Methylation in Breast Cancer by Kim, Dongwook, Shivakumar, Manu, Han, Seonggyun, Sinclair, Michael S, Lee, Young-Ji, Zheng, Yonglan, Olopade, Olufunmilayo I, Kim, Dokyoon, Lee, Younghee

“…Regulation of gene expression by DNA methylation in gene promoter regions is well studied; however, the effects of methylation in the gene body (exons and…”
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LncRNA BLAT1 is Upregulated in Basal-like Breast Cancer through Epigenetic Modifications by Han, Yoo Jane, Boatman, Sonja M., Zhang, Jing, Du, Xinxin C., Yeh, Albert C., Zheng, Yonglan, Mueller, Jeffrey, Olopade, Olufunmilayo I.

“…Long-noncoding RNAs (lncRNAs) have been shown to participate in oncogenesis across a variety of cancers and may represent novel therapeutic targets. However,…”
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Genetic and Epigenetic Regulation of TOX3 Expression in Breast Cancer by Han, Yoo-Jeong, Zhang, Jing, Zheng, Yonglan, Huo, Dezheng, Olopade, Olufunmilayo I

“…Genome wide association studies (GWAS) have identified low penetrance and high frequency single nucleotide polymorphisms (SNPs) that contribute to genetic…”
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Radiogenomics of breast cancer using dynamic contrast enhanced MRI and gene expression profiling by Yeh, Albert C, Li, Hui, Zhu, Yitan, Zhang, Jing, Khramtsova, Galina, Drukker, Karen, Edwards, Alexandra, McGregor, Stephanie, Yoshimatsu, Toshio, Zheng, Yonglan, Niu, Qun, Abe, Hiroyuki, Mueller, Jeffrey, Conzen, Suzanne, Ji, Yuan, Giger, Maryellen L, Olopade, Olufunmilayo I

“…Imaging techniques can provide information about the tumor non-invasively and have been shown to provide information about the underlying genetic makeup…”
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Molecular profiling of a real-world breast cancer cohort with genetically inferred ancestries reveals actionable tumor biology differences between European ancestry and African ancestry patient populations by Miyashita, Minoru, Bell, Joshua S K, Wenric, Stephane, Karaesmen, Ezgi, Rhead, Brooke, Kase, Matthew, Kaneva, Kristiyana, De La Vega, Francisco M, Zheng, Yonglan, Yoshimatsu, Toshio F, Khramtsova, Galina, Liu, Fang, Zhao, Fangyuan, Howard, Frederick M, Nanda, Rita, Beaubier, Nike, White, Kevin P, Huo, Dezheng, Olopade, Olufunmilayo I

“…Endocrine-resistant HR+/HER2- breast cancer (BC) and triple-negative BC (TNBC) are of interest for molecularly informed treatment due to their aggressive…”
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Hypermethylation of the CpG-island near the C9orf72 G₄C₂-repeat expansion in FTLD patients by Xi, Zhengrui, Rainero, Innocenzo, Rubino, Elisa, Pinessi, Lorenzo, Bruni, Amalia C, Maletta, Raffaele G, Nacmias, Benedetta, Sorbi, Sandro, Galimberti, Daniela, Surace, Ezequiel I, Zheng, Yonglan, Moreno, Danielle, Sato, Christine, Liang, Yan, Zhou, Ye, Robertson, Janice, Zinman, Lorne, Tartaglia, Maria Carmela, St George-Hyslop, Peter, Rogaeva, Ekaterina

“…The G₄C₂-repeat expansion in C9orf72 is a common cause of frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS). C9orf72…”
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High prevalence of BRCA1 and BRCA2 mutations in unselected Nigerian breast cancer patients by Fackenthal, James D., Zhang, Jing, Zhang, Bifeng, Zheng, Yonglan, Hagos, Fitsum, Burrill, Devin R., Niu, Qun, Huo, Dezheng, Sveen, Walmy E., Ogundiran, Temidayo, Adebamowo, Clemet, Odetunde, Abayomi, Falusi, Adeyinka G., Olopade, Olufunmilayo I.

“…Inherited mutations in the BRCA1 and BRCA2 genes are the strongest genetic predictors of breast cancer and are the primary causes of familial breast/ovarian…”
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Mutational spectrum of breast cancer susceptibility genes among women ascertained in a cancer risk clinic in Northeast Brazil by Felix, Gabriela E. S., Guindalini, Rodrigo Santa Cruz, Zheng, Yonglan, Walsh, Tom, Sveen, Elisabeth, Lopes, Taisa Manuela Machado, Côrtes, Juliana, Zhang, Jing, Carôzo, Polyanna, Santos, Irlânia, Bonfim, Thaís Ferreira, Garicochea, Bernardo, Toralles, Maria Betânia Pereira, Meyer, Roberto, Netto, Eduardo Martins, Abe-Sandes, Kiyoko, King, Mary-Claire, de Oliveira Nascimento, Ivana Lucia, Olopade, Olufunmilayo I.

“…Purpose There is a paucity of data on the spectrum and prevalence of pathogenic variants among women of African ancestry in the Northeast region of Brazil…”
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Association of Pancreatic Cancer Susceptibility Variants with Risk of Breast Cancer in Women of European and African Ancestry by Wang, Shengfeng, Zheng, Yonglan, Ogundiran, Temidayo O, Ojengbede, Oladosu, Zheng, Wei, Nathanson, Katherine L, Nemesure, Barbara, Ambs, Stefan, Olopade, Olufunmilayo I, Huo, Dezheng

“…Pancreatic cancer mutation signatures closely resemble breast cancer, suggesting that both cancers may have common predisposition mechanisms that may include…”
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Novel germline PALB2 truncating mutations in African American breast cancer patients by Zheng, Yonglan, Zhang, Jing, Niu, Qun, Huo, Dezheng, Olopade, Olufunmilayo I.

“…BACKGROUND: It has been demonstrated that the partner and localizer of breast cancer 2 (PALB2) acts as a bridging molecule between the breast cancer 1 (BRCA1)…”
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Molecular Subtype-Specific Expression of MicroRNA-29c in Breast Cancer Is Associated with CpG Dinucleotide Methylation of the Promoter by Poli, Elizabeth, Zhang, Jing, Nwachukwu, Chika, Zheng, Yonglan, Adedokun, Babatunde, Olopade, Olufunmilayo I, Han, Yoo-Jeong

“…Basal-like breast cancer is a molecularly distinct subtype of breast cancer that is highly aggressive and has a poor prognosis. MicroRNA-29c (miR-29c) has been…”
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Characterizing Genetic Susceptibility to Breast Cancer in Women of African Ancestry by Feng, Ye, Rhie, Suhn Kyong, Huo, Dezheng, Ruiz-Narvaez, Edward A, Haddad, Stephen A, Ambrosone, Christine B, John, Esther M, Bernstein, Leslie, Zheng, Wei, Hu, Jennifer J, Ziegler, Regina G, Nyante, Sarah, Bandera, Elisa V, Ingles, Sue A, Press, Michael F, Deming, Sandra L, Rodriguez-Gil, Jorge L, Zheng, Yonglan, Yao, Song, Han, Yoo-Jeong, Ogundiran, Temidayo O, Rebbeck, Timothy R, Adebamowo, Clement, Ojengbede, Oladosu, Falusi, Adeyinka G, Hennis, Anselm, Nemesure, Barbara, Ambs, Stefan, Blot, William, Cai, Qiuyin, Signorello, Lisa, Nathanson, Katherine L, Lunetta, Kathryn L, Sucheston-Campbell, Lara E, Bensen, Jeannette T, Chanock, Stephen J, Marchand, Loic Le, Olshan, Andrew F, Kolonel, Laurence N, Conti, David V, Coetzee, Gerhard A, Stram, Daniel O, Olopade, Olufunmilayo I, Palmer, Julie R, Haiman, Christopher A

“…Genome-wide association studies have identified approximately 100 common genetic variants associated with breast cancer risk, the majority of which were…”
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Screening RAD51C nucleotide alterations in patients with a family history of breast and ovarian cancer by Zheng, Yonglan, Zhang, Jing, Hope, Kisha, Niu, Qun, Huo, Dezheng, Olopade, Olufunmilayo I.

“…It has been reported that one biallelic missense mutation in the RAD51C gene was found in a Fanconi anemia-like disorder and six monoallelic pathogenic…”
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Recurrent BRCA1 and BRCA2 mutations in breast cancer patients of African ancestry by Zhang, Jing, Fackenthal, James D., Zheng, Yonglan, Huo, Dezheng, Hou, Ningqi, Niu, Qun, Zvosec, Cecilia, Ogundiran, Temidayo O., Hennis, Anselm J., Leske, Maria Cristina, Nemesure, Barbara, Wu, Suh-Yuh, Olopade, Olufunmilayo I.

“…Recurrent mutations constituted nearly three quarters of all BRCA1 mutations and almost half of all BRCA2 mutations identified in the first cohort of the…”
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