Search Results - "Zheng, Xiaohe"
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A CRISPR/Cas13a-powered catalytic electrochemical biosensor for successive and highly sensitive RNA diagnostics
Published in Biosensors & bioelectronics (15-04-2021)“…Rapid and specific quantitation of a variety of RNAs with low expression levels in early-stage cancer is highly desirable but remains a challenge. Here, we…”
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Involvement of S100A8/A9-TLR4-NLRP3 Inflammasome Pathway in Contrast-Induced Acute Kidney Injury
Published in Cellular physiology and biochemistry (01-01-2017)“…Background: Contrast-induced acute kidney injury (CIAKI) is a common cause of hospital-acquired acute kidney injury (AKI). S100A8/A9-TLR4-NLRP3 inflammasome…”
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The core genes of cuproptosis assists in discerning prognostic and immunological traits of clear cell renal cell carcinoma
Published in Frontiers in oncology (21-09-2022)“…ObjectiveCuproptosis, a nascent and unique pattern of cell death, is poised to spark a new rush of biological research. Yet, the subsumed mechanism of…”
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Associations of serum carotenoids with asthma and mortality in the US adults
Published in Heliyon (15-02-2024)“…This study was to investigate the association between serum carotenoid levels and the prevalence of asthma, as well as the relationship between serum…”
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MCC950 Reduces Neuronal Apoptosis in Spinal Cord Injury in Mice
Published in CNS & neurological disorders drug targets (26-10-2021)“…Traumatic Spinal Cord Injury (SCI) is a severe condition usually accompanied by an inflammatory process that gives rise to uncontrolled local apoptosis and a…”
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Acylglycerol Kinase-Targeted Therapies in Oncology
Published in Frontiers in cell and developmental biology (22-07-2021)“…Acylglycerol kinase (AGK) is a recently discovered mitochondrial lipid kinase, and mutation of its gene is the fundamental cause of Sengers syndrome. AGK is…”
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Cuproptosis-associated lncRNAs discern prognosis and immune microenvironment in sarcoma victims
Published in Frontiers in cell and developmental biology (16-12-2022)“…Cuproptosis is a fresh form of the copper-elesclomol-triggered, mitochondrial tricarboxylic acid (TCA) dependent cell death. Yet, the subsumed mechanism of…”
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Glycolysis-Based Genes Are Potential Biomarkers in Thyroid Cancer
Published in Frontiers in oncology (26-04-2021)“…While increased glycolysis has been identified as a cancer marker and attracted much attention in thyroid cancer (THCA), the prognostic role of it remains to…”
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The biology of mitochondrial carrier homolog 2
Published in Mitochondrion (01-03-2024)“…•MTCH2 has been identified as a mitochondrial outer membrane protein insertase.•MTCH2 participate in apoptosis and lipid metabolism.•MTCH2 serves as a positive…”
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10
FDG PET/CT Imaging of Liver and Spleen Histiocytic Sarcoma
Published in Clinical nuclear medicine (01-03-2024)“…Histiocytic sarcoma is a tumor of the lymphohematopoietic system characterized by macrophage morphology and immunophenotype. Here, we report FDG PET/CT images…”
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A signature of immune-related gene pairs predicts oncologic outcomes and response to immunotherapy in lung adenocarcinoma
Published in Genomics (San Diego, Calif.) (01-11-2020)“…In this study, we established the predictive model for lung adenocarcinoma (LUAD) depending on immune-related gene pairs (IRGPs) signature, which could not…”
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A dual amplification-based CRISPR/Cas12a biosensor for sensitive detection of miRNA in prostate cancer
Published in Analytica chimica acta (23-10-2023)“…MicroRNA (miRNA) has gained significant attention as a potential biomarker for cancer clinics, and there is an urgent need for developing sensing strategies…”
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13
Identification of mitochondrial function‐associated lncRNAs in septic mice myocardium
Published in Journal of cellular biochemistry (01-01-2021)“…The present study aimed to analyze long noncoding RNA (lncRNA) and messenger RNA (mRNA) expression profiles in septic mice heart and to identify potential…”
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14
CRISPR-Cas12a powered multifunctional DNA nanodumbbell lock biosensor for multiple molecular detection
Published in Chemical engineering journal (Lausanne, Switzerland : 1996) (15-07-2023)“…•A CRISPR-powered multifunctional detection biosensor was developed.•Three DNA nanodumbbell lock structures were used for multiple molecular…”
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15
CRISPR-Cas12a powered hybrid nanoparticle for extracellular vesicle aggregation and in-situ microRNA detection
Published in Biosensors & bioelectronics (01-02-2024)“…Efficient extracellular vesicle (EV) enrichment and timely internal RNA detection for cancer diagnostics are highly desirable and remain a challenge. Here, we…”
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DNA methylation-based lung adenocarcinoma subtypes can predict prognosis, recurrence, and immunotherapeutic implications
Published in Aging (Albany, NY.) (21-11-2020)“…The marked heterogeneity of lung adenocarcinoma (LUAD) makes its diagnosis and treatment difficult. In addition, the aberrant DNA methylation profile…”
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A new hematological parameter model for the diagnosis and prognosis of sepsis in emergency department: A single‐center retrospective study
Published in International journal of laboratory hematology (01-04-2024)“…Introduction Sepsis, a syndrome of organ dysfunction caused by an unregulated host response to infection. This study aimed to develop a novel sepsis diagnostic…”
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Use of fibrin monomer and D-Dimer in assessing overt and nonovert disseminated intravascular coagulation
Published in Blood coagulation & fibrinolysis (01-06-2021)“…Early diagnosis of disseminated intravascular coagulation (DIC) before its progression to an overt stage is beneficial for its treatment and prognosis.This…”
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Nepetin inhibits osteoclastogenesis by inhibiting RANKL‐induced activation of NF‐κB and MAPK signalling pathway, and autophagy
Published in Journal of cellular and molecular medicine (01-12-2020)“…Aseptic prosthetic loosening due to wear particle–induced inflammatory osteolysis is the main cause of failure for artificial joint replacement. The…”
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Pseudo‐NRBC in the Mindray BC‐6800Plus analyzer: A clue for diagnostic anticipation of fungemia. Experimental and preliminary clinical reports
Published in International journal of laboratory hematology (01-10-2024)“…Introduction Candidemia can be a significant cause of death in immunosuppressed or debilitated patients particularly. Abnormalities of the instrumental…”
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