Search Results - "Zheng, X."
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Recent progress in surface-enhanced Raman spectroscopy for biological and biomedical applications: from cells to clinics
Published in Chemical Society reviews (03-07-2017)“…The application of surface-enhanced Raman spectroscopy (SERS) in biological and biomedical detection schemes is feasible due to its excellent molecular…”
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ADAMTS13 and von Willebrand Factor in Thrombotic Thrombocytopenic Purpura
Published in Annual review of medicine (01-01-2015)“…Pathogenesis of thrombotic thrombocytopenic purpura (TTP) was a mystery for over half a century until the discovery of ADAMTS13. ADAMTS13 is primarily…”
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3
Superoxide dismutase 1 acts as a nuclear transcription factor to regulate oxidative stress resistance
Published in Nature communications (19-03-2014)“…Superoxide dismutase 1 (Sod1) has been known for nearly half a century for catalysis of superoxide to hydrogen peroxide. Here we report a new Sod1 function in…”
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4
Mechanism underlying severe deficiency of plasma ADAMTS-13 activity in immune thrombotic thrombocytopenic purpura
Published in Journal of thrombosis and haemostasis (01-05-2024)“…Immune-mediated thrombotic thrombocytopenic purpura is caused by autoantibodies against ADAMTS-13, a plasma enzyme that cleaves von Willebrand factor. However,…”
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The standard of care for immune thrombotic thrombocytopenic purpura today
Published in Journal of thrombosis and haemostasis (01-08-2021)“…Targeted therapy of immune thrombotic thrombocytopenic purpura (iTTP) requires acurate and prompt diagnosis and differentiation from complement‐mediated…”
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6
CFD simulations of wind flow and mean surface pressure for buildings with balconies: Comparison of RANS and LES
Published in Building and environment (15-04-2020)“…Façade geometrical details can substantially influence the near-façade airflow patterns and pressures. This is especially the case for building balconies as…”
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7
SDF‐StyleGAN: Implicit SDF‐Based StyleGAN for 3D Shape Generation
Published in Computer graphics forum (01-08-2022)“…We present a StyleGAN2‐based deep learning approach for 3D shape generation, called SDF‐StyleGAN, with the aim of reducing visual and geometric dissimilarity…”
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ISTH guidelines for the diagnosis of thrombotic thrombocytopenic purpura
Published in Journal of thrombosis and haemostasis (01-10-2020)“…Background Despite an increase in our understandings of pathogenesis of thrombotic thrombocytopenic purpura (TTP), the approaches for initial diagnosis and…”
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9
Emerging Role of MicroRNAs in mTOR Signaling
Published in Cellular and molecular life sciences : CMLS (01-07-2017)“…Mechanistic target of rapamycin (mTOR) is a conserved serine/threonine kinase that plays a critical role in the control of cellular growth and metabolism…”
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10
Rab1A Is an mTORC1 Activator and a Colorectal Oncogene
Published in Cancer cell (10-11-2014)“…Amino acid (AA) is a potent mitogen that controls growth and metabolism. Here we describe the identification of Rab1 as a conserved regulator of AA signaling…”
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SOD1 regulates ribosome biogenesis in KRAS mutant non-small cell lung cancer
Published in Nature communications (15-04-2021)“…SOD1 is known as the major cytoplasmic superoxide dismutase and an anticancer target. However, the role of SOD1 in cancer is not fully understood. Herein we…”
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ISTH guidelines for treatment of thrombotic thrombocytopenic purpura
Published in Journal of thrombosis and haemostasis (01-10-2020)“…Background Despite advances in treatment options for thrombotic thrombocytopenic purpura (TTP), there are still limited high quality data to inform clinicians…”
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Structure–function and regulation of ADAMTS‐13 protease
Published in Journal of thrombosis and haemostasis (01-06-2013)“…Summary ADAMTS‐13, a plasma reprolysin‐like metalloprotease, cleaves von Willebrand factor (VWF). Severe deficiency of plasma ADAMTS‐13 activity results in…”
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14
Expanding roles of superoxide dismutases in cell regulation and cancer
Published in Drug discovery today (01-01-2016)“…•Superoxide dismutases (SODs) have important regulatory functions in metabolism, signalling and transcription.•SODs are crucial for cancer cell growth,…”
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15
Role of Taste Receptors in Innate Immunity and Oral Health
Published in Journal of Dental Research (01-07-2022)“…Taste receptors are receptor proteins that detect ligands belonging to the 5 taste modalities: sweet, bitter, sour, salty, and umami. Taste receptors are not…”
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Book Review Journal Article -
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A magnetar-powered X-ray transient as the aftermath of a binary neutron-star merger
Published in Nature (London) (01-04-2019)“…Mergers of neutron stars are known to be associated with short γ-ray bursts 1 – 4 . If the neutron-star equation of state is sufficiently stiff (that is, the…”
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Thrombotic thrombocytopenic purpura: pathogenesis, diagnosis and potential novel therapeutics
Published in Journal of thrombosis and haemostasis (01-10-2017)“…Summary Thrombotic thrombocytopenic purpura (TTP), a potentially fatal clinical syndrome, is primarily caused by autoantibodies against the von Willebrand…”
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Breaking Lorentz reciprocity to overcome the time-bandwidth limit in physics and engineering
Published in Science (American Association for the Advancement of Science) (23-06-2017)“…A century-old tenet in physics and engineering asserts that any type of system, having bandwidth Δω, can interact with a wave over only a constrained time…”
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Effects of nitrification inhibitors (DCD and DMPP) on nitrous oxide emission, crop yield and nitrogen uptake in a wheat–maize cropping system
Published in Biogeosciences (11-04-2013)“…The application of nitrification inhibitors together with ammonium-based fertilizers is proposed as a potent method to decrease nitrous oxide (N2O) emission…”
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Trigonometric Parallaxes of High-mass Star-forming Regions: Our View of the Milky Way
Published in The Astrophysical journal (10-11-2019)“…We compile and analyze approximately 200 trigonometric parallaxes and proper motions of molecular masers associated with very young high-mass stars. Most of…”
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