Search Results - "Zheng, Song Guo"
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Hall of Fame among Pro-inflammatory Cytokines: Interleukin-6 Gene and Its Transcriptional Regulation Mechanisms
Published in Frontiers in immunology (19-12-2016)“…Pro-inflammatory cytokines that are generated by immune system cells and mediate many kinds of immune responses are kinds of endogenous polypeptides. They are…”
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ITK signalling via the Ras/IRF4 pathway regulates the development and function of Tr1 cells
Published in Nature communications (21-06-2017)“…Type 1 regulatory T (Tr1) cells differentiate in response to signals engaging the T cell receptor (TCR), express high levels of the immunosuppressive cytokine…”
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The deubiquitinase USP44 promotes Treg function during inflammation by preventing FOXP3 degradation
Published in EMBO reports (03-09-2020)“…The transcription factor forkhead box P3 (FOXP3) is essential for the development of regulatory T cells (Tregs) and their function in immune homeostasis…”
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Beyond Type 1 Regulatory T Cells: Co-expression of LAG3 and CD49b in IL-10-Producing T Cell Lineages
Published in Frontiers in immunology (19-11-2018)“…Type 1 regulatory CD4 T (Tr1) cells express high levels of the immunosuppressive cytokine IL-10 but not the master transcription factor Foxp3, and can suppress…”
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IL-38: A New Player in Inflammatory Autoimmune Disorders
Published in Biomolecules (Basel, Switzerland) (05-08-2019)“…Interleukin (IL)-38, a newly discovered IL-1 family cytokine, is expressed in several tissues and secreted by various cells. IL-38 has recently been reported…”
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The role of all-trans retinoic acid in the biology of Foxp3+ regulatory T cells
Published in Cellular & molecular immunology (01-09-2015)“…Regulatory T (Treg) cells are necessary for immune system homeostasis and the prevention of autoimmune diseases. Foxp3 is specifically expressed in Treg cells…”
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Proteolysis-targeting chimera against BCL-XL destroys tumor-infiltrating regulatory T cells
Published in Nature communications (24-02-2021)“…Regulatory T cells (Tregs) play an important role in maintaining immune homeostasis and, within tumors, their upregulation is common and promotes an…”
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Adoptive transfer of induced-Treg cells effectively attenuates murine airway allergic inflammation
Published in PloS one (09-07-2012)“…Both nature and induced regulatory T (Treg) lymphocytes are potent regulators of autoimmune and allergic disorders. Defects in endogenous Treg cells have been…”
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Small extracellular vesicles derived from human MSCs prevent allergic airway inflammation via immunomodulation on pulmonary macrophages
Published in Cell death & disease (01-06-2020)“…Allergic airway inflammation is a major public health disease that affects up to 300 million people in the world. However, its management remains largely…”
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Author Correction: ITK signalling via the Ras/IRF4 pathway regulates the development and function of Tr1 cells
Published in Nature communications (19-05-2020)“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Cellular differentiation into hyphae and spores in halophilic archaea
Published in Nature communications (01-04-2023)“…Several groups of bacteria have complex life cycles involving cellular differentiation and multicellular structures. For example, actinobacteria of the genus…”
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Addendum: Cellular differentiation into hyphae and spores in halophilic archaea
Published in Nature communications (01-02-2024)Get full text
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13
Bidirectional air–sea exchange and accumulation of POPs (PAHs, PCBs, OCPs and PBDEs) in the nocturnal marine boundary layer
Published in Atmospheric chemistry and physics (25-05-2016)“…As a consequence of long-range transported pollution, air–sea exchange can become a major source of persistent organic pollutants in remote marine…”
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Smad1 and its target gene Wif1 coordinate BMP and Wnt signaling activities to regulate fetal lung development
Published in Development (Cambridge) (01-03-2011)“…Bone morphogenetic protein 4 (Bmp4) is essential for lung development. To define the intracellular signaling mechanisms by which Bmp4 regulates lung…”
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Induced CD4+ forkhead box protein–positive T cells inhibit mast cell function and established contact hypersensitivity through TGF-β1
Published in Journal of allergy and clinical immunology (01-08-2012)“…Background Induced CD4+ forkhead box protein 3–positve regulatory T (iTreg) cells are a promising source for cell-based therapies of established inflammatory…”
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Role of TNF-TNF Receptor 2 Signal in Regulatory T Cells and Its Therapeutic Implications
Published in Frontiers in immunology (19-04-2018)“…Tumor necrosis factor α (TNFα) is a pleiotropic cytokine which signals through TNF receptor 1 (TNFR1) and TNF receptor 2 (TNFR2). Emerging evidence has…”
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Differential roles of TNFα-TNFR1 and TNFα-TNFR2 in the differentiation and function of CD4+Foxp3+ induced Treg cells in vitro and in vivo periphery in autoimmune diseases
Published in Cell death & disease (10-01-2019)“…Tumor Necrosis Factor (TNF) α is a multifunctional cytokine with pro-inflammatory and anti-inflammatory characteristics. Increasing evidence suggests that…”
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Mesenchymal Stem Cell-Derived Exosomes: A Promising Biological Tool in Nanomedicine
Published in Frontiers in pharmacology (25-01-2021)“…As nano-scale biological vesicles, extracellular vesicles (EVs)/exosomes, in particular, exosomes derived from mesenchymal stem cells (MSC-exosomes), have been…”
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Reduction of arsenic toxicity in two rice cultivar seedlings by different nanoparticles
Published in Ecotoxicology and environmental safety (15-09-2018)“…In this study, we investigated arsenic uptake and enzymatic activities in rice seedlings after the addition of nanoparticles. Hydroponic experiments were…”
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Transfer of regulatory T cells generated ex vivo modifies graft rejection through induction of tolerogenic CD4+CD25+ cells in the recipient
Published in International immunology (01-02-2006)“…Certain CD4+CD25+ T cells can induce and maintain T-cell non-responsiveness to donor alloantigens and have therapeutic potential in solid organ…”
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