Search Results - "Zheng, LeMei"
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Understanding the roles and regulation patterns of circRNA on its host gene in tumorigenesis and tumor progression
Published in Journal of Experimental and Clinical Cancer Research (15-04-2023)“…Circular RNAs (circRNAs) are a novel type of endogenous non-coding RNAs, which are covalently closed loop structures formed by precursor mRNAs (pre-mRNAs)…”
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NOP2/Sun RNA methyltransferase 2 is a potential pan-cancer prognostic biomarker and is related to immunity
Published in PloS one (28-09-2023)“…NOP2/Sun RNA methyltransferase 2 (NSUN2), an important methyltransferase of m5C, has been poorly studied in cancers, and the relationship between NSUN2 and…”
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Dissecting the roles and clinical potential of YY1 in the tumor microenvironment
Published in Frontiers in oncology (04-04-2023)“…Yin-Yang 1 (YY1) is a member of the GLI-Kruppel family of zinc finger proteins and plays a vital dual biological role in cancer as an oncogene or a tumor…”
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Ferroptosis: a critical mechanism of N6-methyladenosine modification involved in carcinogenesis and tumor progression
Published in Science China. Life sciences (01-06-2024)“…Ferroptosis is an iron-dependent regulatory cell necrosis induced by iron overload and lipid peroxidation. It occurs when multiple redox-active enzymes are…”
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BRD7 inhibits enhancer activity and expression of BIRC2 to suppress tumor growth and metastasis in nasopharyngeal carcinoma
Published in Cell death & disease (14-02-2023)“…BRD7 functions as a crucial tumor suppressor in numerous malignancies including nasopharyngeal carcinoma (NPC). However, its function and exact mechanisms…”
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The Emerging Roles and Clinical Potential of circSMARCA5 in Cancer
Published in Cells (Basel, Switzerland) (30-09-2022)“…Circular RNAs (circRNAs) are a type of endogenous non-coding RNA and a critical epigenetic regulation way that have a closed-loop structure and are highly…”
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CircBRD7 attenuates tumor growth and metastasis in nasopharyngeal carcinoma via epigenetic activation of its host gene
Published in Cancer science (01-01-2024)“…BRD7 was identified as a tumor suppressor in nasopharyngeal carcinoma (NPC). Circular RNAs (CircRNAs) are involved in the occurrence and development of NPC as…”
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The emerging roles of the interaction between m6A modification and c‐Myc in driving tumorigenesis and development
Published in Journal of cellular physiology (01-07-2022)“…N6‐methyladenosine (m6A) is an extremely common and conservative posttranscriptional modification, that can specifically target and regulate the expression or…”
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TRIM28 promotes tumor growth and metastasis in breast cancer by targeting the BRD7 protein for ubiquitination and degradation
Published in Cellular oncology (Dordrecht) (01-10-2024)“…Purpose Bromodomain-containing protein 7 (BRD7) is downregulated and functions as a tumor suppressor in many types of cancers including breast cancer, and the…”
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10
Ferroptosis: a critical mechanism of N 6 -methyladenosine modification involved in carcinogenesis and tumor progression
Published in Science China. Life sciences (01-06-2024)“…Ferroptosis is an iron-dependent regulatory cell necrosis induced by iron overload and lipid peroxidation. It occurs when multiple redox-active enzymes are…”
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Journal Article -
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Deciphering the vital roles and mechanism of m5C modification on RNA in cancers
Published in American journal of cancer research (2023)“…5-methylcytosine (m5C modification) plays an essential role in tumors, which affects different types of RNA, the expression of downstream target genes, and…”
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Validation of Core Ingredients and Molecular Mechanism of Cinobufotalin Injection Against Liver Cancer
Published in Drug design, development and therapy (01-01-2024)“…Cinobufotalin injection has obvious curative effects on liver cancer patients with less toxicity and fewer side effects than other therapeutic approaches…”
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Yin Yang 1 suppresses tumor invasion and metastasis in nasopharyngeal carcinoma by negatively regulating eIF4E transcriptional activity and expression
Published in American journal of cancer research (01-01-2023)“…Tumor metastasis is a leading cause of death in nasopharyngeal carcinoma (NPC) patients. Previous research has identified that transcription factor Yin Yang 1…”
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NOP2/Sun RNA methyltransferase 2 is a potential pan-cancer prognostic biomarker and is related to immunity
Published in PloS one (01-01-2023)Get full text
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