Search Results - "Zheng, Jinzi"
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Research on Passenger Flow Assignment of High-Speed Trains Based on Personalized Itinerary Choice
Published in Discrete dynamics in nature and society (2020)“…Under the condition that ticket fare for high-speed train could fluctuate around a benchmark price in China, aimed at predicting how the passengers will…”
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An integrated augmented reality surgical navigation platform using multi-modality imaging for guidance
Published in PloS one (30-04-2021)“…An integrated augmented reality (AR) surgical navigation system that potentially improves intra-operative visualization of concealed anatomical structures…”
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A mathematical model of the enhanced permeability and retention effect for liposome transport in solid tumors
Published in PloS one (02-12-2013)“…The discovery of the enhanced permeability and retention (EPR) effect has resulted in the development of nanomedicines, including liposome-based formulations…”
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APN/CD13-targeting as a strategy to alter the tumor accumulation of liposomes
Published in Journal of controlled release (25-09-2011)“…Targeting angiogenic vasculature has been validated as a viable approach for cancer imaging and therapy. The tumor vasculature-specific ligand…”
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Heat-activated thermosensitive liposomal cisplatin (HTLC) results in effective growth delay of cervical carcinoma in mice
Published in Journal of controlled release (28-03-2014)“…Cisplatin (CDDP) has been identified as the primary chemotherapeutic agent for the treatment of cervical cancer, but dose limiting toxicity is a key issue…”
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In vivo performance of a liposomal vascular contrast agent for CT and MR-based image guidance applications
Published in Pharmaceutical research (01-06-2007)“…This study evaluated the in vivo performance of a liposome formulation that co-encapsulates iohexol and gadoteridol as a multimodal contrast agent for computed…”
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Quantitative CT Imaging of the Spatial and Temporal Distribution of Liposomes in a Rabbit Tumor Model
Published in Molecular pharmaceutics (06-04-2009)“…Successful employment of noninvasive imaging techniques to quantitatively assess the in vivo pharmacokinetics and biodistribution of nanoparticle drug delivery…”
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Cyclophosphamide-Mediated Tumor Priming for Enhanced Delivery and Antitumor Activity of HER2-Targeted Liposomal Doxorubicin (MM-302)
Published in Molecular cancer therapeutics (01-09-2015)“…Given the bulky nature of nanotherapeutics relative to small molecules, it is hypothesized that effective tumor delivery and penetration are critical barriers…”
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A novel minimally invasive technique to create a rabbit VX2 lung tumor model for nano-sized image contrast and interventional studies
Published in PloS one (28-06-2013)“…The rabbit VX2 lung cancer model is a large animal model useful for preclinical lung cancer imaging and interventional studies. However, previously reported…”
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Correction to: Longitudinal PET Imaging to Monitor Treatment Efficacy by Liposomal Irinotecan in Orthotopic Patient-Derived Pancreatic Tumor Models of High and Low Hypoxia
Published in Molecular imaging and biology (01-04-2021)“…A Correction to this paper has been published: https://doi.org/10.1007/s11307-020-01566-w…”
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Nanoparticle-based CT visualization of pulmonary vasculature for minimally-invasive thoracic surgery planning
Published in PloS one (17-01-2019)“…To evaluate CF800, a novel lipid-based liposomal nanoparticle that co-encapsulates indocyanine green (ICG) and iohexol, for CT imaging of pulmonary vasculature…”
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The translocator protein ligand [18F]DPA-714 images glioma and activated microglia in vivo
Published in European journal of nuclear medicine and molecular imaging (01-05-2012)“…Purpose In recent years there has been an increase in the development of radioligands targeting the 18-kDa translocator protein (TSPO). TSPO expression is well…”
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Longitudinal PET Imaging to Monitor Treatment Efficacy by Liposomal Irinotecan in Orthotopic Patient-Derived Pancreatic Tumor Models of High and Low Hypoxia
Published in Molecular imaging and biology (01-06-2020)“…Purpose Hypoxia is linked to aggressiveness, resistance to therapy, and poor prognosis of pancreatic tumors. Liposomal irinotecan (nal-IRI, ONIVYDE®) has shown…”
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Spatiotemporal assessment of spontaneous metastasis formation using multimodal in vivo imaging in HER2+ and triple negative metastatic breast cancer xenograft models in mice
Published in PloS one (03-05-2018)“…Preclinical breast cancer models recapitulating the clinical course of metastatic disease are crucial for drug development. Highly metastatic cell lines…”
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Differential Expression of the 18 kDa Translocator Protein (TSPO) by Neoplastic and Inflammatory Cells in Mouse Tumors of Breast Cancer
Published in Molecular pharmaceutics (06-06-2011)“…Tumor-associated inflammation has been linked to angiogenesis, metastasis and poor prognosis. The 18 kDa translocator protein (TSPO), also known as the…”
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Ticket Fare Optimization for China’s High-Speed Railway Based on Passenger Choice Behavior
Published in Discrete dynamics in nature and society (01-01-2017)“…Although China’s high-speed railway (HSR) is maturing after more than ten years of construction and development, the load factor and revenue of HSR could still…”
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Evaluation of PET Imaging Performance of the TSPO Radioligand [18F]DPA-714 in Mouse and Rat Models of Cancer and Inflammation
Published in Molecular imaging and biology (01-02-2016)“…Purpose Many radioligands have been explored for imaging the 18-kDa translocator protein (TSPO), a diagnostic and therapeutic target for inflammation and…”
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Targeting Focal Adhesion Kinase with Dominant-Negative FRNK or Hsp90 Inhibitor 17-DMAG Suppresses Tumor Growth and Metastasis of SiHa Cervical Xenografts
Published in Cancer research (Chicago, Ill.) (01-06-2009)“…Focal adhesion kinase (FAK), a nonreceptor protein tyrosine kinase and key modulator of integrin signaling, is widely expressed in different tissues and cell…”
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Multimodal Contrast Agent for Combined Computed Tomography and Magnetic Resonance Imaging Applications
Published in Investigative radiology (01-03-2006)“…OBJECTIVE:The objective of this study was to examine the feasibility of a multimodal system to effectively induce and maintain contrast enhancement in both…”
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Companion Diagnostic 64Cu-Liposome Positron Emission Tomography Enables Characterization of Drug Delivery to Tumors and Predicts Response to Cancer Nanomedicines
Published in Theranostics (01-01-2018)“…Deposition of liposomal drugs into solid tumors is a potentially rate-limiting step for drug delivery and has substantial variability that may influence…”
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