Search Results - "Zheng, Janet H."
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BOK Is a Non-canonical BCL-2 Family Effector of Apoptosis Regulated by ER-Associated Degradation
Published in Cell (07-04-2016)“…The mitochondrial pathway of apoptosis is initiated by mitochondrial outer membrane permeabilization (MOMP). The BCL-2 family effectors BAX and BAK are thought…”
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Discoveries and controversies in BCL‐2 protein‐mediated apoptosis
Published in The FEBS journal (01-07-2016)“…B‐cell lymphoma 2 (BCL‐2) family proteins mediate mitochondrial apoptosis by regulating mitochondrial outer membrane permeabilization (MOMP), which leads to…”
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Metastability, an emerging concept governing BOK-mediated apoptosis initiation
Published in Oncotarget (24-07-2018)Get full text
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Intrinsic Instability of BOK Enables Membrane Permeabilization in Apoptosis
Published in Cell reports (Cambridge) (15-05-2018)“…The effector B cell lymphoma-2 (BCL-2) protein BCL-2 ovarian killer (BOK) induces mitochondrial outer membrane permeabilization (MOMP) to initiate apoptosis…”
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