Search Results - "Zheng, Hu‐Yong"

Outcome of children with newly diagnosed acute lymphoblastic leukemia treated with CCLG‐ALL 2008: The first nation‐wide prospective multicenter study in China by Cui, Lei, Li, Zhi‐Gang, Chai, Yi‐Huan, Yu, Jie, Gao, Ju, Zhu, Xiao‐Fan, Jin, Run‐Ming, Shi, Xiao‐Dong, Zhang, Le‐Ping, Gao, Yi‐Jin, Zhang, Rui‐Dong, Zheng, Hu‐Yong, Hu, Shao‐Yan, Cui, Ying‐Hui, Zhu, Yi‐Ping, Zou, Yao, Ng, Margaret H. L., Xiao, Yan, Li, Jun‐Hui, Zhang, Yong‐Hong, He, Hai‐Long, Xian, Ying, Wang, Tian‐You, Li, Chi‐Kong, Wu, Min‐Yuan

“…Acute lymphoblastic leukemia (ALL) is the most common malignancy among children. The trial Chinese Children Leukemia Group (CCLG)‐ALL 2008 was a prospective…”
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Current Treatment for Central Nervous System Involvement in Children with Hemophagocytic Lymphohistiocytosis by Zheng, Hu-Yong

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Acute Myeloid Leukemia： Advancements in Diagnosis and Treatment by Yu, Meng-Ge, Zheng, Hu-Yong

“…Objective： Leukemia is the most common pediatric malignancy and a major cause of morbidity and mortality in children. Among all subtypes, a lack of consensus…”
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β-catenin promotes MTX resistance of leukemia cells by down-regulating FPGS expression via NF-κB by Liu, Shu-Guang, Yue, Zhi-Xia, Li, Zhi-Gang, Zhang, Rui-Dong, Zheng, Hu-Yong, Zhao, Xiao-Xi, Gao, Chao

“…Aberrant activation of β-catenin has been shown to play important roles in the chemoresistance of acute lymphoblastic leukemia (ALL), but the involvement and…”
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Clinical-biological characteristics and treatment outcomes of pediatric pro-B ALL patients enrolled in BCH-2003 and CCLG-2008 protocol: a study of 121 Chinese children by Gao, Chao, Liu, Shu-Guang, Yue, Zhi-Xia, Liu, Yi, Liang, Jing, Li, Jun, Zhang, Yuan-Yuan, Yu, Jiao-Le, Wu, Ying, Lin, Wei, Zheng, Hu-Yong, Zhang, Rui-Dong

“…Although leukemic blast cells of Pro-B cell acute lymphoblastic leukemia (ALL) are arrested at the same stage of B cell differentiation, the immature B cell…”
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Downregulating CREBBP inhibits proliferation and cell cycle progression and induces daunorubicin resistance in leukemia cells by Gao, Chao, Liu, Shu-Guang, Lu, Wen-Ting, Yue, Zhi-Xia, Zhao, Xiao-Xi, Xing, Tian-Yu, Chen, Zhen-Ping, Zheng, Hu-Yong, Li, Zhi-Gang

“…Low expression levels of CREB‑binding protein (CREBBP) have been demonstrated to be associated with high minimal residual disease at the end of induction…”
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The prognostic potential of coilin in association with p27 expression in pediatric acute lymphoblastic leukemia for disease relapse by Yue, Zhi-Xia, Gao, Rui-Qi, Gao, Chao, Liu, Shu-Guang, Zhao, Xiao-Xi, Xing, Tian-Yu, Niu, Jing, Li, Zhi-Gang, Zheng, Hu-Yong, Ding, Wei

“…Cajal body (CB) is a nucleic organelle where small nuclear ribonucleoproteins undergo modification, maturation, splicing and/or assembly. Coilin is the marker…”
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Low CREBBP expression is associated with adverse long‐term outcomes in paediatric acute lymphoblastic leukaemia by Gao, Chao, Zhang, Rui‐Dong, Liu, Shu‐Guang, Zhao, Xiao‐Xi, Cui, Lei, Yue, Zhi‐Xia, Li, Wei‐Jing, Chen, Zhen‐Ping, Li, Zhi‐Gang, Rao, Qing, Wang, Min, Zheng, Hu‐Yong, Wang, Jian‐Xiang

“…Objectives CREBBP alterations are associated with many diseases including leukaemia. However, CREBBP expression and its clinical relevance in paediatric acute…”
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NOTCH1 mutations are associated with favourable long‐term prognosis in paediatric T‐cell acute lymphoblastic leukaemia: a retrospective study of patients treated on BCH‐2003 and CCLG‐2008 protocol in China by Gao, Chao, Liu, Shu‐Guang, Zhang, Rui‐Dong, Li, Wei‐Jing, Zhao, Xiao‐Xi, Cui, Lei, Wu, Min‐Yuan, Zheng, Hu‐Yong, Li, Zhi‐Gang

“…Summary Activating mutations of NOTCH1 are a common occurrence in T‐cell acute lymphoblastic leukaemia (T‐ALL), but its impact on T‐ALL treatment is still…”
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Infections During Induction Therapy of Protocol CCLG-2008 in Childhood Acute Lymphoblastic Leukemia： A Single-center Experience with 256 Cases in China by Li, Si-Dan, Chen, Yong-Bing, Li, Zhi-Gang, Wu, Run-Hui, Qin, Mao-Quan, Zhou, Xuan, Jiang, Jin, Zhang, Rui-Dong, Xie, Jing, Ma, Xiao-Li, Zhang, Rui, Wang, Bin, Wu, Ying, Zheng, Hu-Yong, Wu, Min-Yuan

“…Background：Infections remain a major cause of therapy-associated morbidity and mortality in children with acute lymphoblastic leukemia （ALL）.Methods：We…”
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Effects of SLCO1B1 on Elimination and Toxicities of High-Dose Methotrexate in Pediatric Acute Lymphoblastic Leukemia by Yang, Fei-Fei, Xue, Tian-Lin, Gao, Chao, Wu, Ying, Lin, Wei, Li, Jun, Zhang, Rui-Dong, Zheng, Hu-Yong, Liu, Shu-Guang

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Polymorphisms in methotrexate transporters and their relationship to plasma methotrexate levels, toxicity of high-dose methotrexate, and outcome of pediatric acute lymphoblastic leukemia by Liu, Shu-Guang, Gao, Chao, Zhang, Rui-Dong, Zhao, Xiao-Xi, Cui, Lei, Li, Wei-Jing, Chen, Zhen-Ping, Yue, Zhi-Xia, Zhang, Yuan-Yuan, Wu, Min-Yuan, Wang, Jian-Xiang, Li, Zhi-Gang, Zheng, Hu-Yong

“…High-dose methotrexate (HDMTX) plays an important role in the treatment of acute lymphoblastic leukemia (ALL) although there is great inter-patient variability…”
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Prognostic significance of NOTCH1/FBXW7 mutations in pediatric T cell acute lymphoblastic leukemia: a study of minimal residual disease risk-directed CCLG-ALL 2008 treatment protocol by Yuan, Yuan, Li, Jun, Xue, Tian-Lin, Hu, Hai-Rui, Lin, Wei, Liu, Shu-Guang, Zhang, Rui-Dong, Zheng, Hu-Yong, Gao, Chao

“…NOTCH1/FBXW7 mutation is common in T-cell acute lymphoblastic leukemia (T-ALL), but controversy looms on its prognostic significance. We screened 98 pediatric…”
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Clinical Characteristics and Outcome Analysis of 94 Children With Brain Abscess in Beijing: A Single-center Retrospective Study by Dou, Zhen-Zhen, Guo, Ling-Yun, Liu, Lin-Lin, Li, Mu-Han, Hu, Hui-Li, Hu, Bing, Guo, Xin, Chen, Tian-Ming, Chen, He-Ying, Ge, Ming, Qian, Su-Yun, Zheng, Hu-Yong, Li, Jiu-Wei, Zhang, Wei-Hua, Hei, Ming-Yan, Liu, Gang

“…BACKGROUND:There are limit studies about pediatric brain abscess in China. The aim of this study was to analyze clinical characteristics and outcomes of…”
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Frequency distribution of five SNPs in human GGH gene and their effects on clinical outcomes of Chinese pediatric patients with acute lymphoblastic leukemia by Li, Miao, Wang, Shu-Mei, Wu, Wan-Shui, Yan, Dan, Zhang, Le-Ping, Zheng, Hu-Yong

“…Methotrexate (MTX) is widely used in the treatment of childhood acute lymphoblastic leukemia (ALL). Gamma-glutamyl hydrolase (GGH) plays an important role in…”
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Combined analysis of IKZF1 deletions and CRLF2 expression on prognostic impact in pediatric B-cell precursor acute lymphoblastic leukemia by Cui, Lei, Gao, Chao, Wang, Chan-Juan, Zhao, Xiao-Xi, Li, Wei-Jing, Li, Zhi-Gang, Zheng, Hu-Yong, Wang, Tian-You, Zhang, Rui-Dong

“…This study aimed to investigate the combined impact of IKZF1 deletions/high expression of CRLF2 on the prognosis of pediatric B-cell precursor acute…”
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Low expressions of ARS2 and CASP8AP2 predict relapse and poor prognosis in pediatric acute lymphoblastic leukemia patients treated on China CCLG-ALL 2008 protocol by Cui, Lei, Gao, Chao, Zhang, Rui-Dong, Jiao, Ying, Li, Wei-Jing, Zhao, Xiao-Xi, Liu, Shu-Guang, Yue, Zhi-Xia, Zheng, Hu-Yong, Deng, Guo-Ren, Wu, Min-Yuan, Li, Zhi-Gang, Jia, Hong-Ti

“…Highlights • Low expression of ARS2 was a useful indicator for relapse in pediatric acute lymphoblastic leukemia. • Combined assessment of ARS2 and CASP8AP2…”
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Central nervous system relapse in a pediatric anaplastic large cell lymphoma patient with CLTC/ALK translocation treated with alectinib: A case report by Yang, Jing, Li, Jun, Gu, Wei-Yue, Jin, Ling, Duan, Yan-Long, Huang, Shuang, Zhang, Meng, Wang, Xi-Si, Liu, Yi, Zhou, Chun-Ju, Gao, Chao, Zheng, Hu-Yong, Zhang, Yong-Hong

“…The aberrant expression of the anaplastic lymphoma kinase ( ) gene in ALK-positive (ALK+) anaplastic large cell lymphoma (ALCL) is usually due to…”
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FPGS rs1544105 polymorphism is associated with treatment outcome in pediatric B-cell precursor acute lymphoblastic leukemia by Liu, Shu-Guang, Gao, Chao, Zhang, Rui-Dong, Jiao, Ying, Cui, Lei, Li, Wei-Jing, Chen, Zhen-Ping, Wu, Min-Yuan, Zheng, Hu-Yong, Zhao, Xiao-Xi, Yue, Zhi-Xia, Li, Zhi-Gang

“…Folypolyglutamate synthase (FPGS) catalyzes the polyglutamation of folates and antifolates, such as methotrexate (MTX), to produce highly active metabolites…”
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Progress of studies on genetics of childhood acute leukemia by Yue, Zhi-Xia, Zheng, Hu-Yong

“…This study on determination of leukemia-specific chromosomal abnormalities and their relationship with prognosis of childhood acute leukemia (AL) had an…”
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