Search Results - "Zhen, James"

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  1. 1

    Structures and comparison of endogenous 2-oxoglutarate and pyruvate dehydrogenase complexes from bovine kidney by Liu, Shiheng, Xia, Xian, Zhen, James, Li, Zihang, Zhou, Z. Hong

    Published in Cell discovery (22-11-2022)
    “…The α-keto acid dehydrogenase complex family catalyzes the essential oxidative decarboxylation of α-keto acids to yield acyl-CoA and NADH. Despite performing…”
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    Journal Article
  2. 2

    Segmental structural dynamics in Aβ42 globulomers by Yoon, Allison, Zhen, James, Guo, Zhefeng

    “…Aβ42 aggregation plays a central role in the pathogenesis of Alzheimer’s disease. In addition to the insoluble fibrils that comprise the amyloid plaques, Aβ42…”
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    Journal Article
  3. 3

    Screening Tests for Lasso Problems by Xiang, Zhen James, Yun Wang, Ramadge, Peter J.

    “…This paper is a survey of dictionary screening for the lasso problem. The lasso problem seeks a sparse linear combination of the columns of a dictionary to…”
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    Journal Article
  4. 4

    Static and dynamic disorder in Aβ40 fibrils by Xiao, Hui, Duo, Lan, Zhen, James, Wang, Hongsu, Guo, Zhefeng

    “…Deposition of Aβ aggregates in the form of amyloid fibrils is a pathological hallmark of Alzheimer's disease. Understanding the structure and dynamics of Aβ…”
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    Journal Article
  5. 5

    Structures From Cells and Viruses Through Endogenous CryoEm Methods by Zhen, James

    Published 01-01-2024
    “…As we seek to elucidate the functions and mechanisms of biological constructs, there is a growing need to learn about their structures in their native contexts…”
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    Dissertation
  6. 6

    Structural basis of RNA conformational switching in the transcriptional regulator 7SK RNP by Yang, Yuan, Liu, Shiheng, Egloff, Sylvain, Eichhorn, Catherine D., Hadjian, Tanya, Zhen, James, Kiss, Tamás, Zhou, Z. Hong, Feigon, Juli

    Published in Molecular cell (05-05-2022)
    “…7SK non-coding RNA (7SK) negatively regulates RNA polymerase II (RNA Pol II) elongation by inhibiting positive transcription elongation factor b (P-TEFb), and…”
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    Journal Article
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    Fast lasso screening tests based on correlations by Xiang, Z. J., Ramadge, P. J.

    “…Representing a vector as a sparse linear combination of codewords, e.g. by solving a lasso problem, lies at the heart of many machine learning and statistics…”
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    Conference Proceeding
  10. 10

    Edge-Preserving Image Regularization Based on Morphological Wavelets and Dyadic Trees by Xiang, Z. J., Ramadge, P. J.

    Published in IEEE transactions on image processing (01-04-2012)
    “…Despite the tremendous success of wavelet-based image regularization, we still lack a comprehensive understanding of the exact factor that controls edge…”
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    Journal Article
  11. 11

    Lasso screening with a small regularization parameter by Yun Wang, Xiang, Zhen James, Ramadge, Peter J.

    “…Screening for lasso problems is a means of quickly reducing the size of the dictionary needed to solve a given instance without impacting the optimality of the…”
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    Conference Proceeding
  12. 12

    Tradeoffs in improved screening of lasso problems by Yun Wang, Xiang, Zhen James, Ramadge, Peter J.

    “…Recently, methods of screening the lasso problem have been developed that use the target vector x to quickly identify a subset of columns of the dictionary…”
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    Conference Proceeding
  13. 13

    Morphological wavelets and the complexity of dyadic trees by Xiang, Zhen James, Ramadge, Peter J.

    “…In this paper we reveal a connection between the coefficients of the morphological wavelet transform and complexity measures of dyadic tree representations of…”
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    Conference Proceeding
  14. 14

    Combining structural knowledge with sparsity in machine learning and signal processing by Xiang, Zhen James

    Published 01-01-2012
    “…With the advancement of technology, we are able to collect, store, and transmit an ever-increasing volume of data. However, our ability to extract useful…”
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    Dissertation
  15. 15

    Sparse boosting by Xiang, Z.J., Ramadge, P.J.

    “…We propose a boosting algorithm that seeks to minimize the AdaBoost exponential loss of a composite classifier using only a sparse set of base classifiers. The…”
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    Conference Proceeding
  16. 16

    Learning a wavelet tree for multichannel image denoising by Xiang, Z. J., Zhuo Zhang, Pingmei Xu, Ramadge, P. J.

    “…We propose a new multichannel image denoising algorithm. To exploit important inter-channel dependencies, we first use dynamic programming to learn an explicit…”
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    Conference Proceeding
  17. 17

    Morphological wavelet transform with adaptive dyadic structures by Xiang, Z J, Ramadge, P J

    “…We propose a two component method for denoising multidimensional signals, e.g. images. The first component uses a dynamic programing algorithm of complexity O…”
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    Conference Proceeding
  18. 18

    Screening Tests for Lasso Problems by Xiang, Zhen James, Wang, Yun, Ramadge, Peter J

    Published 21-08-2016
    “…This paper is a survey of dictionary screening for the lasso problem. The lasso problem seeks a sparse linear combination of the columns of a dictionary to…”
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    Journal Article
  19. 19

    Combining structural knowledge with sparsity in machine learning and signal processing by Xiang, Zhen James

    “…With the advancement of technology, we are able to collect, store, and transmit an ever-increasing volume of data. However, our ability to extract useful…”
    Get full text
    Dissertation
  20. 20

    Genetic algorithms in machine learning and optimization by Tu, James Zhen

    Published 01-01-1992
    “…This dissertation focuses on the development of the theory of genetic algorithms and its applications in machine learning and optimization. A genetic-based…”
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    Dissertation