Search Results - "Zharikova, Anastasia"

Expression of SARS-CoV-2 entry factors in lung epithelial stem cells and its potential implications for COVID-19 by Valyaeva, Anna A., Zharikova, Anastasia A., Kasianov, Artem S., Vassetzky, Yegor S., Sheval, Eugene V.

“…SARS-CoV-2 can infiltrate the lower respiratory tract, resulting in severe respiratory failure and a high death rate. Normally, the airway and alveolar…”
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OrthoQuantum: visualizing evolutionary repertoire of eukaryotic proteins by Ilnitskiy, Ivan S, Zharikova, Anastasia A, Mironov, Andrey A

“…Abstract Extensive amounts of data from next-generation sequencing and omics studies have led to the accumulation of information that provides insight into the…”
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Gut Microbiota as a Source of Uremic Toxins by Popkov, Vasily A, Zharikova, Anastasia A, Demchenko, Evgenia A, Andrianova, Nadezda V, Zorov, Dmitry B, Plotnikov, Egor Y

“…Uremic retention solutes are the compounds that accumulate in the blood when kidney excretory function is impaired. Some of these compounds are toxic at high…”
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SARS‐CoV‐2 cellular tropism and direct multiorgan failure in COVID‐19 patients: Bioinformatic predictions, experimental observations, and open questions by Valyaeva, Anna A., Zharikova, Anastasia A., Sheval, Eugene V.

“…Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), the virus that causes coronavirus disease 2019 (COVID‐19), has led to an unprecedented public…”
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Do Extracellular Vesicles Derived from Mesenchymal Stem Cells Contain Functional Mitochondria? by Zorova, Ljubava D., Kovalchuk, Sergei I., Popkov, Vasily A., Chernikov, Valery P., Zharikova, Anastasia A., Khutornenko, Anastasia A., Zorov, Savva D., Plokhikh, Konstantin S., Zinovkin, Roman A., Evtushenko, Ekaterina A., Babenko, Valentina A., Pevzner, Irina B., Shevtsova, Yulia A., Goryunov, Kirill V., Plotnikov, Egor Y., Silachev, Denis N., Sukhikh, Gennady T., Zorov, Dmitry B.

“…Extracellular vesicles (EV) derived from stem cells have become an effective complement to the use in cell therapy of stem cells themselves, which has led to…”
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Compensatory reactions of B cells in response to chronic HIV-1 Tat exposure by Valyaeva, Anna A, Tikhomirova, Maria A, Feng, Junyi, Zharikova, Anastasia A, Potashnikova, Daria M, Musinova, Yana R, Mironov, Andrey A, Vassetzky, Yegor S, Sheval, Eugene V

“…Patients infected with human immunodeficiency virus-1 (HIV-1) have an increased incidence of B-cell lymphoma, even though HIV-1 does not infect B cells. The…”
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Intragenic compensation through the lens of deep mutational scanning by Azbukina, Nadezhda, Zharikova, Anastasia, Ramensky, Vasily

“…A significant fraction of mutations in proteins are deleterious and result in adverse consequences for protein function, stability, or interaction with other…”
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Applicability of Diagnostic Criteria and High Prevalence of Familial Dysbetalipoproteinemia in Russia: A Pilot Study by Blokhina, Anastasia V, Ershova, Alexandra I, Kiseleva, Anna V, Sotnikova, Evgeniia A, Zharikova, Anastasia A, Zaicenoka, Marija, Vyatkin, Yuri V, Ramensky, Vasily E, Kutsenko, Vladimir A, Shalnova, Svetlana A, Meshkov, Alexey N, Drapkina, Oxana M

“…Familial dysbetalipoproteinemia (FD) is a highly atherogenic genetically based lipid disorder with an underestimated actual prevalence. In recent years,…”
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Analysis of the brain transcriptome, microbiome and metabolome in ketogenic diet and experimental stroke by Zharikova, Anastasia A., Andrianova, Nadezda V., Silachev, Denis N., Nebogatikov, Vladimir O., Pevzner, Irina B., Makievskaya, Ciara I., Zorova, Ljubava D., Maleev, Grigoriy V., Baydakova, Galina V., Chistyakov, Dmitry V., Goriainov, Sergey V., Sergeeva, Marina G., Burakova, Inna Y., Gureev, Artem P., Popkov, Vasily A., Ustyugov, Aleksey A., Plotnikov, Egor Y.

“…•KD affected brain gene expression, gut microbiome and blood metabolic profile.•Stroke induced alteration in brain transcriptome toward damage pattern.•Stroke…”
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Mesenchymal stromal cell-derived extracellular vesicles afford neuroprotection by modulating PI3K/AKT pathway and calcium oscillations by Turovsky, Egor A., Golovicheva, Victoria V., Varlamova, Elena G., Danilina, Tatyana I., Goryunov, Kirill V., Shevtsova, Yulia A., Pevzner, Irina B., Zorova, Ljubava D., Babenko, Valentina A., Evtushenko, Ekaterina A., Zharikova, Anastasia A., Khutornenko, Anastasia A., Kovalchuk, Sergey I., Plotnikov, Egor Y., Zorov, Dmitry B., Sukhikh, Gennady T., Silachev, Denis N.

“…Mesenchymal stromal cells (MSC) are widely recognized as potential effectors in neuroprotective therapy. The protective properties of MSC were considered to be…”
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Differential Analysis of A-to-I mRNA Edited Sites in Parkinson's Disease by Pozdyshev, Denis V, Zharikova, Anastasia A, Medvedeva, Maria V, Muronetz, Vladimir I

“…Parkinson's disease (PD) is a widespread neuronal degenerative disorder with unexplored etiology. It is associated with various pathological events. In…”
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BaRDIC: robust peak calling for RNA–DNA interaction data by Mylarshchikov, Dmitry E, Nikolskaya, Arina I, Bogomaz, Olesja D, Zharikova, Anastasia A, Mironov, Andrey A

“…Abstract Chromatin-associated non-coding RNAs play important roles in various cellular processes by targeting genomic loci. Two types of genome-wide NGS…”
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Targeted Sequencing of 242 Clinically Important Genes in the Russian Population From the Ivanovo Region by Ramensky, Vasily E., Ershova, Alexandra I., Zaicenoka, Marija, Kiseleva, Anna V., Zharikova, Anastasia A., Vyatkin, Yuri V., Sotnikova, Evgeniia A., Efimova, Irina A., Divashuk, Mikhail G., Kurilova, Olga V., Skirko, Olga P., Muromtseva, Galina A., Belova, Olga A., Rachkova, Svetlana A., Pokrovskaya, Maria S., Shalnova, Svetlana A., Meshkov, Alexey N., Drapkina, Oxana M.

“…We performed a targeted sequencing of 242 clinically important genes mostly associated with cardiovascular diseases in a representative population sample of…”
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A Rare Coincidence of Three Inherited Diseases in a Family with Cardiomyopathy and Multiple Extracardiac Abnormalities by Bukaeva, Anna, Myasnikov, Roman, Kulikova, Olga, Meshkov, Alexey, Kiseleva, Anna, Petukhova, Anna, Zotova, Evgenia, Sparber, Peter, Ershova, Alexandra, Sotnikova, Evgeniia, Kudryavtseva, Maria, Zharikova, Anastasia, Koretskiy, Sergey, Mershina, Elena, Ramensky, Vasily, Zaicenoka, Marija, Vyatkin, Yuri, Muraveva, Alisa, Abisheva, Alexandra, Nikityuk, Tatiana, Sinitsyn, Valentin, Divashuk, Mikhail, Dadali, Elena, Pokrovskaya, Maria, Drapkina, Oxana

“…A genetic diagnosis of primary cardiomyopathies can be a long-unmet need in patients with complex phenotypes. We investigated a three-generation family with…”
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Noncompaction cardiomyopathy is caused by a novel in‐frame desmin (DES) deletion mutation within the 1A coiled‐coil rod segment leading to a severe filament assembly defect by Marakhonov, Andrey V., Brodehl, Andreas, Myasnikov, Roman P., Sparber, Peter A., Kiseleva, Anna V., Kulikova, Olga V., Meshkov, Alexey N., Zharikova, Anastasia A., Koretsky, Serguey N., Kharlap, Maria S., Stanasiuk, Caroline, Mershina, Elena A., Sinitsyn, Valentin E., Shevchenko, Alexey O., Mozheyko, Natalia P., Drapkina, Oksana M., Boytsov, Sergey A., Milting, Hendrik, Skoblov, Mikhail Yu

“…Mutations in DES, encoding desmin protein, are associated with different kinds of skeletal and/or cardiac myopathies. However, it is unknown, whether DES…”
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Hemi- and Homozygous Loss-of-Function Mutations in DSG2 (Desmoglein-2) Cause Recessive Arrhythmogenic Cardiomyopathy with an Early Onset by Brodehl, Andreas, Meshkov, Alexey, Myasnikov, Roman, Kiseleva, Anna, Kulikova, Olga, Klauke, Bärbel, Sotnikova, Evgeniia, Stanasiuk, Caroline, Divashuk, Mikhail, Pohl, Greta Marie, Kudryavtseva, Maria, Klingel, Karin, Gerull, Brenda, Zharikova, Anastasia, Gummert, Jan, Koretskiy, Sergey, Schubert, Stephan, Mershina, Elena, Gärtner, Anna, Pilus, Polina, Laser, Kai Thorsten, Sinitsyn, Valentin, Boytsov, Sergey, Drapkina, Oxana, Milting, Hendrik

“…About 50% of patients with arrhythmogenic cardiomyopathy (ACM) carry a pathogenic or likely pathogenic mutation in the desmosomal genes. However, there is a…”
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The Double Mutation DSG2-p.S363X and TBX20-p.D278X Is Associated with Left Ventricular Non-Compaction Cardiomyopathy: Case Report by Myasnikov, Roman, Brodehl, Andreas, Meshkov, Alexey, Kulikova, Olga, Kiseleva, Anna, Pohl, Greta Marie, Sotnikova, Evgeniia, Divashuk, Mikhail, Klimushina, Marina, Zharikova, Anastasia, Pokrovskaya, Maria, Koretskiy, Sergey, Kharlap, Maria, Mershina, Elena, Sinitsyn, Valentin, Basargina, Elena, Gandaeva, Leila, Barskiy, Vladimir, Boytsov, Sergey, Milting, Hendrik, Drapkina, Oxana

“…Left ventricular non-compaction cardiomyopathy (LVNC) is a rare heart disease, with or without left ventricular dysfunction, which is characterized by a…”
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Ectopic expression of HIV-1 Tat modifies gene expression in cultured B cells: implications for the development of B-cell lymphomas in HIV-1-infected patients by Valyaeva, Anna A, Tikhomirova, Maria A, Potashnikova, Daria M, Bogomazova, Alexandra N, Snigiryova, Galina P, Penin, Aleksey A, Logacheva, Maria D, Arifulin, Eugene A, Shmakova, Anna A, Germini, Diego, Kachalova, Anastasia I, Saidova, Aleena A, Zharikova, Anastasia A, Musinova, Yana R, Mironov, Andrey A, Vassetzky, Yegor S, Sheval, Eugene V

“…An increased frequency of B-cell lymphomas is observed in human immunodeficiency virus-1 (HIV-1)-infected patients, although HIV-1 does not infect B cells…”
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FACS Isolation of Viable Cells in Different Cell Cycle Stages from Asynchronous Culture for RNA Sequencing by Potashnikova, Daria M, Golyshev, Sergey A, Penin, Alexey A, Logacheva, Maria D, Klepikova, Anna V, Zharikova, Anastasia A, Mironov, Andrey A, Sheval, Eugene V, Vorobjev, Ivan A

“…Recently developed high-throughput analytical techniques (e.g., protein mass spectrometry and nucleic acid sequencing) allow unprecedentedly sensitive,…”
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Identification of Pathogenic Variant Burden and Selection of Optimal Diagnostic Method Is a Way to Improve Carrier Screening for Autosomal Recessive Diseases by Sotnikova, Evgeniia A., Kiseleva, Anna V., Kutsenko, Vladimir A., Zharikova, Anastasia A., Ramensky, Vasily E., Divashuk, Mikhail G., Vyatkin, Yuri V., Klimushina, Marina V., Ershova, Alexandra I., Revazyan, Karina Z., Skirko, Olga P., Zaicenoka, Marija, Efimova, Irina A., Pokrovskaya, Maria S., Kopylova, Oksana V., Glechan, Anush M., Shalnova, Svetlana A., Meshkov, Alexey N., Drapkina, Oxana M.

“…Cystic fibrosis, phenylketonuria, alpha-1 antitrypsin deficiency, and sensorineural hearing loss are among the most common autosomal recessive diseases, which…”
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