Search Results - "Zhao, Zhizhuang J"

Plasma exosome microRNAs are indicative of breast cancer by Hannafon, Bethany N, Trigoso, Yvonne D, Calloway, Cameron L, Zhao, Y Daniel, Lum, David H, Welm, Alana L, Zhao, Zhizhuang J, Blick, Kenneth E, Dooley, William C, Ding, W Q

“…microRNAs are promising candidate breast cancer biomarkers due to their cancer-specific expression profiles. However, efforts to develop circulating breast…”
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RBPJ Mutations Identified in Two Families Affected by Adams-Oliver Syndrome by Hassed, Susan J., Wiley, Graham B., Wang, Shaofeng, Lee, Ji-Yun, Li, Shibo, Xu, Weihong, Zhao, Zhizhuang J., Mulvihill, John J., Robertson, James, Warner, James, Gaffney, Patrick M.

“…Through exome resequencing, we identified two unique mutations in recombination signal binding protein for immunoglobulin kappa J (RBPJ) in two independent…”
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Protein tyrosine phosphatase Meg2 dephosphorylates signal transducer and activator of transcription 3 and suppresses tumor growth in breast cancer by Su, Fuqin, Ren, Fangli, Rong, Yu, Wang, Yangmeng, Geng, Yongtao, Wang, Yinyin, Feng, Mengyao, Ju, Yanfang, Li, Yi, Zhao, Zhizhuang J, Meng, Kun, Chang, Zhijie

“…Signal transducer and activator of transcription 3 (STAT3) is over-activated or phosphorylated in breast cancers. The hyper-phosphorylation of STAT3 was…”
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Thrombopoietin is required for full phenotype expression in a JAK2V617F transgenic mouse model of polycythemia vera by Spivak, Jerry L., Merchant, Akil, Williams, Donna M., Rogers, Ophelia, Zhao, Wanke, Duffield, Amy, Resar, Linda S., Moliterno, Alison R., Zhao, Zhizhuang J.

“…The myeloproliferative neoplasms, polycythemia vera, essential thrombocytosis and primary myelofibrosis are hematopoietic stem cell disorders and share driver…”
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Generation of a new congenic mouse strain with enhanced chymase expression in mast cells by Jin, Xi, Zhao, Wanke, Shi, Kaiyao, Ho, Wanting T, Zhao, Zhizhuang J

“…Mast cells are effector cells best known for their roles in IgE-associated allergy, but they also play a protective role in defense against pathogens. These…”
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Development of a highly sensitive method for detection of JAK2V617F by Zhao, Anna H, Gao, Rufei, Zhao, Zhizhuang J

“…Ph- myeloproliferative neoplasms (MPNs) represent a heterogeneous group of chronic diseases characterized by increased expansion of hematopoietic cells of the…”
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Phenotype risk scores identify patients with unrecognized Mendelian disease patterns by Bastarache, Lisa, Hughey, Jacob J, Hebbring, Scott, Marlo, Joy, Zhao, Wanke, Ho, Wanting T, Van Driest, Sara L, McGregor, Tracy L, Mosley, Jonathan D, Wells, Quinn S, Temple, Michael, Ramirez, Andrea H, Carroll, Robert, Osterman, Travis, Edwards, Todd, Ruderfer, Douglas, Velez Edwards, Digna R, Hamid, Rizwan, Cogan, Joy, Glazer, Andrew, Wei, Wei-Qi, Feng, QiPing, Brilliant, Murray, Zhao, Zhizhuang J, Cox, Nancy J, Roden, Dan M, Denny, Joshua C

“…Genetic association studies often examine features independently, potentially missing subpopulations with multiple phenotypes that share a single cause. We…”
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Lack of blinding of outcome assessors in animal model experiments implies risk of observer bias by Bello, Segun, Krogsbøll, Lasse T, Gruber, Jan, Zhao, Zhizhuang J, Fischer, Doris, Hróbjartsson, Asbjørn

“…Abstract Objectives To examine the impact of not blinding outcome assessors on estimates of intervention effects in animal experiments modeling human clinical…”
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Protein-tyrosine Phosphatase PTPN9 Negatively Regulates ErbB2 and Epidermal Growth Factor Receptor Signaling in Breast Cancer Cells by Yuan, Taichang, Wang, Yongping, Zhao, Zhizhuang J., Gu, Haihua

“…ErbB family of the receptor protein-tyrosine kinase plays an important role in the progression of human cancers including breast cancer. Finding…”
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Finding new lanes: Chimeric antigen receptor (CAR) T‐cells for myeloid leukemia by Pratap, Suraj, Zhao, Zhizhuang J.

“…Background Myeloid leukemia represents a heterogeneous group of cancers of blood and bone marrow which arise from clonal expansion of hematopoietic myeloid…”
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Relevance of JAK2V617F positivity to hematological diseases--survey of samples from a clinical genetics laboratory by Zhao, Wanming, Gao, Rufei, Lee, Jiyun, Xing, Shu, Ho, Wanting T, Fu, Xueqi, Li, Shibo, Zhao, Zhizhuang J

“…JAK2V617F is found in the majority of patients with Ph- myeloproliferative neoplasms (MPNs) and has become a valuable marker for diagnosis of MPNs. However, it…”
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Beneficial and harmful effects of alcohol exposure on Caenorhabditis elegans worms by Yu, Xiaokun, Zhao, Wanming, Ma, Junfeng, Fu, Xueqi, Zhao, Zhizhuang J.

“…► Long-term ethanol exposure has hormetic effects on Caenorhabditis elegans. ► Low-concentration ethanol extends lifespan of C. elegans. ► The…”
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Elevated levels of mast cells are involved in pruritus associated with polycythemia vera in JAK2V617F transgenic mice by Jin, Xi, Zhao, Wanke, Kirabo, Annet, Park, Sung O, Ho, Wanting T, Sayeski, Peter P, Zhao, Zhizhuang J

“…Pruritus occurs frequently in patients with polycythemia vera (PV), and the pathophysiology of PV-associated pruritus is unclear. We have previously…”
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miR-543 regulates the epigenetic landscape of myelofibrosis by targeting TET1 and TET2 by Fuentes-Mattei, Enrique, Bayraktar, Recep, Manshouri, Taghi, Silva, Andreia M, Ivan, Cristina, Gulei, Diana, Fabris, Linda, Soares do Amaral, Nayra, Mur, Pilar, Perez, Cristina, Torres-Claudio, Elizabeth, Dragomir, Mihnea P, Badillo-Perez, Adriana, Knutsen, Erik, Narayanan, Pranav, Golfman, Leonard, Shimizu, Masayoshi, Zhang, Xinna, Zhao, Wanke, Ho, Wanting Tina, Estecio, Marcos Roberto, Bartholomeusz, Geoffrey, Tomuleasa, Ciprian, Berindan-Neagoe, Ioana, Zweidler-McKay, Patrick A, Estrov, Zeev, Zhao, Zhizhuang J, Verstovsek, Srdan, Calin, George A, Redis, Roxana S

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miR-543 regulates the epigenetic landscape of myelofibrosis by targeting TET1 and TET2 by Fuentes-Mattei, Enrique, Bayraktar, Recep, Manshouri, Taghi, Silva, Andreia M, Ivan, Cristina, Gulei, Diana, Fabris, Linda, Soares do Amaral, Nayra, Mur, Pilar, Perez, Cristina, Torres-Claudio, Elizabeth, Dragomir, Mihnea P, Badillo-Perez, Adriana, Knutsen, Erik, Narayanan, Pranav, Golfman, Leonard, Shimizu, Masayoshi, Zhang, Xinna, Zhao, Wanke, Ho, Wanting Tina, Estecio, Marcos Roberto, Bartholomeusz, Geoffrey, Tomuleasa, Ciprian, Berindan-Neagoe, Ioana, Zweidler-McKay, Patrick A, Estrov, Zeev, Zhao, Zhizhuang J, Verstovsek, Srdan, Calin, George A, Redis, Roxana S

“…Myelofibrosis (MF) is a myeloproliferative neoplasm characterized by cytopenia and extramedullary hematopoiesis, resulting in splenomegaly. Multiple…”
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The Small Molecule Inhibitor G6 Significantly Reduces Bone Marrow Fibrosis and the Mutant Burden in a Mouse Model of Jak2-Mediated Myelofibrosis by Kirabo, Annet, Park, Sung O, Wamsley, Heather L, Gali, Meghanath, Baskin, Rebekah, Reinhard, Mary K, Zhao, Zhizhuang J, Bisht, Kirpal S, Keserű, György M, Cogle, Christopher R, Sayeski, Peter P

“…Philadelphia chromosome–negative myeloproliferative neoplasms, including polycythemia vera, essential thrombocytosis, and myelofibrosis, are disorders…”
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Identification of a variant form of tyrosine phosphatase LYP by Wang, Shaofeng, Dong, Hongbo, Han, Jiayu, Ho, Wanting T, Fu, Xueqi, Zhao, Zhizhuang J

“…Protein tyrosine phosphatases (PTPs) are important cell signaling regulators with major pathological implications. LYP (also known as PTPN22) is an…”
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SHP‐1 dephosphorylates 3BP2 and potentially downregulates 3BP2‐mediated T cell antigen receptor signaling by Yu, Zhenbao, Maoui, Meryem, Zhao, Zhizhuang J., Li, Yang, Shen, Shi‐Hsiang

“…Src homology 2 (SH2) domain‐containing protein tyrosine phosphatase‐1 (SHP‐1) is a critical inhibitory regulator in T cell‐receptor (TCR) signaling. However,…”
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The Fms-Like Tyrosine Kinase Receptor 3 Ligand/Dendritic Cell Axis Contributes to Kidney Recovery in AKI: SA-PO104 by Guo, Yao, Xie, Chuy, Lu, Meihua, Zhang, Dengyang, Zhao, Yuming, Chen, Jiasi, Zheng, Zhihua, Chen, Yun, Zhao, Zhizhuang J.

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High Expression of Mincle in Intermediate Monocytes of Patients with Autoimmune Diseases: PO1442 by Li, Shuping, Cheng, Lokyu, Cui, Tianjiao, Zhang, Lanyue, Tian, Xiuxun, Zhao, Zhizhuang J., Chen, Yun, Zheng, Zhihua

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