Search Results - "Zhao, Yang O"
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Gut Microbiota of the Tick Vector Ixodes scapularis Modulate Colonization of the Lyme Disease Spirochete
Published in Cell host & microbe (15-01-2014)“…Arthopods such as Ixodes scapularis ticks serve as vectors for many human pathogens. The arthropod gut presents a pivotal microbial entry point and determines…”
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ELF4 is critical for induction of type I interferon and the host antiviral response
Published in Nature immunology (01-12-2013)“…Induction of type I interferon is a central event of antiviral immune responses. Fikrig and colleagues show that the transcription factor ELF4 is recruited by…”
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Ixodes scapularis JAK-STAT Pathway Regulates Tick Antimicrobial Peptides, Thereby Controlling the Agent of Human Granulocytic Anaplasmosis
Published in The Journal of infectious diseases (15-10-2012)“…Ixodes scapularis transmits the agent of human granulocytic anaplasmosis, among other pathogens. The mechanisms used by the tick to control Anaplasma…”
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Coordinated loading of IRG resistance GTPases on to the Toxoplasma gondii parasitophorous vacuole
Published in Cellular microbiology (01-07-2010)“…The immunity-related GTPases (IRGs) constitute an interferon-induced intracellular resistance mechanism in mice against Toxoplasma gondii. IRG proteins…”
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Enhanced survival of Plasmodium-infected mosquitoes during starvation
Published in PloS one (10-07-2012)“…Plasmodium spp. are pathogenic to their vertebrate hosts and also apparently, impose a fitness cost on their insect vectors. We show here, however, that…”
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Plasmodium falciparum phosphoethanolamine methyltransferase is essential for malaria transmission
Published in Proceedings of the National Academy of Sciences - PNAS (05-11-2013)“…Efficient transmission of Plasmodium species between humans and Anopheles mosquitoes is a major contributor to the global burden of malaria. Gametocytogenesis,…”
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Molecular interactions that enable movement of the Lyme disease agent from the tick gut into the hemolymph
Published in PLoS pathogens (01-06-2011)“…Borrelia burgdorferi, the causative agent of Lyme disease, is transmitted to humans by bite of Ixodes scapularis ticks. The mechanisms by which the bacterium…”
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Anopheles gambiae Circumsporozoite Protein-Binding Protein Facilitates Plasmodium Infection of Mosquito Salivary Glands
Published in The Journal of infectious diseases (01-10-2013)“…Malaria, a mosquito-borne disease caused by Plasmodium species, causes substantial morbidity and mortality throughout the world. Plasmodium sporozoites mature…”
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An in vivo transfection approach elucidates a role for Aedes aegypti thioester-containing proteins in flaviviral infection
Published in PloS one (27-07-2011)“…Mosquitoes transmit pathogens that cause infectious diseases of global importance. Techniques to easily introduce genes into mosquitoes, however, limit…”
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Localisation and mislocalisation of the interferon-inducible immunity-related GTPase, Irgm1 (LRG-47) in mouse cells
Published in PloS one (13-01-2010)“…Irgm1 (LRG-47) is an interferon-inducible Golgi membrane associated GTPase of the mouse whose disruption causes susceptibility to many different intracellular…”
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Disruption of the Toxoplasma gondii Parasitophorous Vacuole by IFNγ-Inducible Immunity-Related GTPases (IRG Proteins) Triggers Necrotic Cell Death
Published in PLoS pathogens (01-02-2009)“…Toxoplasma gondii is a natural intracellular protozoal pathogen of mice and other small mammals. After infection, the parasite replicates freely in many cell…”
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Innexin AGAP001476 Is Critical for Mediating Anti-Plasmodium Responses in Anopheles Mosquitoes
Published in The Journal of biological chemistry (05-09-2014)“…The Toll and IMD pathways are known to be induced upon Plasmodium berghei and Plasmodium falciparum infection, respectively. It is unclear how Plasmodium or…”
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Disruption of the Toxoplasma gondii parasitophorous vacuole by IFNgamma-inducible immunity-related GTPases (IRG proteins) triggers necrotic cell death
Published in PLoS pathogens (01-02-2009)“…Toxoplasma gondii is a natural intracellular protozoal pathogen of mice and other small mammals. After infection, the parasite replicates freely in many cell…”
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Localisation and Mislocalisation of the Interferon-Inducible Immunity-Related GTPase, Irgm1
Published in PloS one (13-01-2010)“…Irgm1 (LRG-47) is an interferon-inducible Golgi membrane associated GTPase of the mouse whose disruption causes susceptibility to many different intracellular…”
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Disruption of the Toxoplasma gondii Parasitophorous Vacuole by IFN[gamma]-Inducible Immunity-Related GTPases (IRG Proteins) Triggers Necrotic Cell Death: e1000288
Published in PLoS pathogens (01-02-2009)“…Toxoplasma gondii is a natural intracellular protozoal pathogen of mice and other small mammals. After infection, the parasite replicates freely in many cell…”
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A triplet mechanism for the formation of thymine-thymine (6-4) dimers in UV-irradiated DNA
Published in Physical chemistry chemical physics : PCCP (21-05-2011)“…The reaction pathway for the photochemical formation of thymine-thymine (6-4) dimers in DNA is explored using hybrid density functional theory techniques in…”
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Disease progression patterns of SHIV-KB9 in rhesus macaques of Chinese origin in comparison with Indian macaques
Published in Biomedical and environmental sciences (01-08-2008)“…To develop a model of SHIV-KB9/Chinese origin rhesus (Ch Rh) macaques for vaccine research and to compare the pathogenesis of SHIV-KB9 in Ch Rh macaques with…”
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18F-FDG PET/CT makes a significant contribution to diagnosis of malignancy in patients with cervical lymphadenopathy: a study using optimal scale regression tests
Published in Chinese medical journal (01-02-2013)“…Background The specificity and precision of lymphadenopathy assessment using US, CT and MRI are generally unsatisfactory, while fluorodeoxyglucose-positron…”
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Potential polyphenol markers of phase change in apple ( Malus domestica)
Published in Journal of plant physiology (01-05-2007)“…In order to identify potential biochemical markers that can be used as indicators for phase change, the dynamics of polyphenolic compounds across apple…”
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