Search Results - "Zhao, Xiangshan"
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1
Histological, molecular and functional subtypes of breast cancers
Published in Cancer biology & therapy (15-11-2010)“…Increased understanding of the molecular heterogeneity that is intrinsic to the various subtypes of breast cancer will likely shape the future of breast cancer…”
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2
Distinct effects of EGFR ligands on human mammary epithelial cell differentiation
Published in PloS one (04-10-2013)“…Based on gene expression patterns, breast cancers can be divided into subtypes that closely resemble various developmental stages of normal mammary epithelial…”
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3
Mutant PIK3CA Induces EMT in a Cell Type Specific Manner
Published in PloS one (12-12-2016)“…Breast cancer is characterized into different molecular subtypes, and each subtype is characterized by differential gene expression that are associated with…”
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4
Multiple elements regulate nuclear/cytoplasmic shuttling of FOXO1: characterization of phosphorylation- and 14-3-3-dependent and -independent mechanisms
Published in Biochemical journal (15-03-2004)“…FOXO1, a Forkhead transcription factor, is an important target of insulin and growth factor action. Phosphorylation of Thr-24, Ser-256 and Ser-319 promotes…”
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5
Overexpression of Ecdysoneless in Pancreatic Cancer and Its Role in Oncogenesis by Regulating Glycolysis
Published in Clinical cancer research (15-11-2012)“…To study the expression and function of a novel cell-cycle regulatory protein, human ecdysoneless (Ecd), during pancreatic cancer pathogenesis…”
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6
Telomerase-immortalized human mammary stem/progenitor cells with ability to self-renew and differentiate
Published in Proceedings of the National Academy of Sciences - PNAS (10-08-2010)“…There is increasing evidence that breast and other cancers originate from and are maintained by a small fraction of stem/progenitor cells with self-renewal…”
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7
Anticancer activity of Celastrol in combination with ErbB2-targeted therapeutics for treatment of ErbB2-overexpressing breast cancers
Published in Cancer biology & therapy (15-01-2011)“…The receptor tyrosine kinase ErbB2 is overexpressed in up to a third of breast cancers, allowing targeted therapy with ErbB2-directed humanized antibodies such…”
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8
Derivation of myoepithelial progenitor cells from bipotent mammary stem/progenitor cells
Published in PloS one (13-04-2012)“…There is increasing evidence that breast and other cancers originate from and are maintained by a small fraction of stem/progenitor cells with self-renewal…”
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9
Ada3 Requirement for HAT Recruitment to Estrogen Receptors and Estrogen-Dependent Breast Cancer Cell Proliferation
Published in Cancer research (Chicago, Ill.) (15-12-2007)“…We have previously shown that evolutionarily conserved alteration/deficiency in activation (Ada) protein associates with and promotes estrogen receptor…”
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10
Shared signaling pathways in normal and breast cancer stem cells
Published in Journal of carcinogenesis (2011)“…Recent advances in our understanding of breast cancer biology have led to the identification of a subpopulation of cells within tumors that appear to be…”
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11
Overexpression of a novel cell cycle regulator ecdysoneless in breast cancer: a marker of poor prognosis in HER2/neu-overexpressing breast cancer patients
Published in Breast cancer research and treatment (01-07-2012)“…Uncontrolled proliferation is one of the hallmarks of breast cancer. We have previously identified the human Ecd protein (human ortholog of Drosophila…”
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12
Cytoplasmic localization of alteration/deficiency in activation 3 (ADA3) predicts poor clinical outcome in breast cancer patients
Published in Breast cancer research and treatment (01-02-2013)“…Transcriptional activation by estrogen receptor (ER) is a key step to breast oncogenesis. Given previous findings that ADA3 is a critical component of HAT…”
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13
Overexpression of RhoA Induces Preneoplastic Transformation of Primary Mammary Epithelial Cells
Published in Cancer research (Chicago, Ill.) (15-01-2009)“…Rho family small GTPases serve as molecular switches in the regulation of diverse cellular functions, including actin cytoskeleton remodeling, cell migration,…”
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14
Human Nudel and NudE as Regulators of Cytoplasmic Dynein in Poleward Protein Transport along the Mitotic Spindle
Published in Molecular and Cellular Biology (01-02-2003)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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15
Cyclooxygenase-2 Expression during Immortalization and Breast Cancer Progression
Published in Cancer research (Chicago, Ill.) (15-01-2008)“…Identification of molecular aberrations in premalignant human mammary epithelial cells (hMEC), the precursors for breast cancers, is a central goal in breast…”
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16
Distinct Roles for Rho Versus Rac/Cdc42 GTPases Downstream of Vav2 in Regulating Mammary Epithelial Acinar Architecture
Published in The Journal of biological chemistry (08-01-2010)“…Non-malignant mammary epithelial cells (MECs) undergo acinar morphogenesis in three-dimensional Matrigel culture, a trait that is lost upon oncogenic…”
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17
Eradication of cancer stem cells in triple negative breast cancer using doxorubicin/pluronic polymeric micelles
Published in Nanomedicine (01-02-2020)“…The potency of polymeric micelle-based doxorubicin, SP1049C, against cancer stem cells (CSCs) in triple negative breast cancer (TNBC) is evaluated. CSCs with…”
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18
Treatment of Brackish Water RO Brine via Bipolar Membrane Electrodialysis
Published in Industrial & engineering chemistry research (24-02-2021)“…Due to the demand for acid and base in brackish water reverse osmosis (RO) desalination plants located in remote areas and the difficulty of transporting acid…”
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19
Abstract 2115: An authenticated in vitro model for prostate microenvironment studies utilizing prostate epithelial cells and stromal-derived cells
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…Abstract Prostate cancer remains one of the most common cancers diagnosed in men and one of the leading causes of cancer death in men. Tumor development and…”
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20
A field study of desalination of high-salinity surface brackish water via an RO-NF hybrid system
Published in Chemical engineering research & design (01-06-2022)“…In this work, a pilot-scale membrane desalination demonstration system for producing drinking water from surface brackish water with a total dissolved solids…”
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