Search Results - "Zhao, Tingxiu"
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Dioscin potentiates the antitumor effect of suicide gene therapy in melanoma by gap junction intercellular communication-mediated antigen cross-presentation
Published in Biomedicine & pharmacotherapy (01-06-2022)“…Dioscin (Dio), steroid saponin, exists in several medicinal herbs with potent anticancer efficacy. This study aimed to explore the effect of Dio on the…”
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Integrated analysis reveals the pivotal interactions between immune cells in the melanoma tumor microenvironment
Published in Scientific reports (16-06-2022)“…Melanoma is the most lethal type of skin cancer. Despite the breakthroughs in the clinical treatment of melanoma using tumor immunotherapy, many patients do…”
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Metabolomics Reveals the Mechanisms for the Pulmonary Toxicity of Siegesbeckia orientalis L. and the Toxicity-Reducing Effect of Processing
Published in Frontiers in pharmacology (09-08-2021)“…Siegesbeckia orientalis L. (SO) is a commonly used Chinese medicinal herb. It has long been used as a remedy in traditional Chinese medicine (TCM) for symptoms…”
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Identification of Fangjihuangqi Decoction as a late-stage autophagy inhibitor with an adjuvant anti-tumor effect against non-small cell lung cancer
Published in Chinese medicine (07-06-2023)“…Clinically, although chemotherapy is one of the most commonly used methods of treating tumors, chemotherapeutic drugs can induce autophagic flux and increase…”
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Pathway network-based quantitative modeling of the time-dependent and dose-response anti-inflammatory effect of Reduning Injection
Published in Journal of ethnopharmacology (10-05-2023)“…Traditional Chinese medicine (TCM) has extensive healing effects on inflammatory diseases with few side effects. Reduning injection (RDNI), a TCM prescription…”
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Integrated metabolomics and network pharmacology to reveal the mechanisms of Processed Aurantii Fructus in the treatment of CUMS-induced functional dyspepsia
Published in Journal of ethnopharmacology (30-01-2025)“…[Display omitted] •PAF effectively treats CUMS-induced FD.•JAK2/STAT3 is a potential pathway for PAF in treating CUMS-induced FD…”
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Comprehensive quality evaluation of fermented‐steaming Fructus Aurantii based on chemical composition, flavor characteristics, and intestinal microbial community
Published in Journal of food science (01-05-2024)“…Fructus Aurantii (FA) is an edible and medicinal functional food used worldwide that enhances digestion. Since raw FA (RFA) possesses certain side effects for…”
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Identification of Fangchinoline as a novel autophagy inhibitor with an adjuvant of chemotherapy against lung cancer
Published in Toxicology and applied pharmacology (15-10-2023)“…Autophagy is a fundamental recycling pathway that enhances cellular resilience, promoting survival. However, this survival mechanism can impede anti-cancer…”
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Berbamine Hydrochloride inhibits lysosomal acidification by activating Nox2 to potentiate chemotherapy-induced apoptosis via the ROS-MAPK pathway in human lung carcinoma cells
Published in Cell biology and toxicology (01-08-2023)“…Autophagy is typically activated in cancer cells as a rescue strategy in response to cellular stress (e.g., chemotherapy). Herein, we found that Berbamine…”
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Network Pharmacology and Experimental Evidence Reveal Dioscin Suppresses Proliferation, Invasion, and EMT via AKT/GSK3b/mTOR Signaling in Lung Adenocarcinoma
Published in Drug design, development and therapy (01-01-2020)“…Dioscin, a natural glycoside derived from many plants, has been proved to exert anti-cancer activity. Several studies have found that it reverses…”
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