Search Results - "Zhao, Robert C. H."

Epigenetic dysregulation in mesenchymal stem cell aging and spontaneous differentiation by Li, Zhilong, Liu, Chenxiong, Xie, Zhenhua, Song, Pengyue, Zhao, Robert C H, Guo, Ling, Liu, Zhigang, Wu, Yaojiong

“…Mesenchymal stem cells (MSCs) hold great promise for the treatment of difficult diseases. As MSCs represent a rare cell population, ex vivo expansion of MSCs…”
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The Size of Mesenchymal Stem Cells is a Significant Cause of Vascular Obstructions and Stroke by Ge, Jianfeng, Guo, Ling, Wang, Shan, Zhang, Yiling, Cai, Ting, Zhao, Robert C. H., Wu, Yaojiong

“…Background and Purpose Intravascular injection of mesenchymal stem cells (MSCs) has been found to cause considerable vascular obstructions which may lead to…”
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The Role of Chemokines in Mesenchymal Stem Cell Homing to Myocardium by Wu, Yaojiong, Zhao, Robert C. H.

“…A growing body of preclinical evidence suggests that mesenchymal stem cells (MSCs) are effective for the structural and functional recovery of the infracted…”
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Concise Review: Bone Marrow‐Derived Stem/Progenitor Cells in Cutaneous Repair and Regeneration by Wu, Yaojiong, Zhao, Robert C. H., Tredget, Edward E.

“…Our understanding of the role of bone marrow (BM)‐derived cells in cutaneous homeostasis and wound healing had long been limited to the contribution of…”
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Mesenchymal stem cells induce mature dendritic cells into a novel Jagged-2–dependent regulatory dendritic cell population by Zhang, Bin, Liu, Rui, Shi, Dan, Liu, Xingxia, Chen, Yuan, Dou, Xiaowei, Zhu, Xishan, Lu, Chunhua, Liang, Wei, Liao, Lianming, Zenke, Martin, Zhao, Robert C.H.

“…Mesenchymal stem cells (MSCs), in addition to their multilineage differentiation, exert immunomodulatory effects on immune cells, even dendritic cells (DCs)…”
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Mesenchymal stem/stromal cells induce the generation of novel IL-10-dependent regulatory dendritic cells by SOCS3 activation by Liu, Xingxia, Qu, Xuebin, Chen, Yuan, Liao, Lianming, Cheng, Kai, Shao, Changshun, Zenke, Martin, Keating, Armand, Zhao, Robert C H

“…Suppression of immune response by mesenchymal stem/stromal cells (MSCs) is well documented. However, their regulatory effects on immune cells, especially…”
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Sca-1+Lin-CD117- mesenchymal stem/stromal cells induce the generation of novel IRF8-controlled regulatory dendritic cells through Notch-RBP-J signaling by Liu, Xingxia, Ren, Shaoda, Ge, Chaozhuo, Cheng, Kai, Zenke, Martin, Keating, Armand, Zhao, Robert C H

“…Mesenchymal stem/stromal cells (MSCs) can influence the destiny of hematopoietic stem/progenitor cells (HSCs) and exert broadly immunomodulatory effects on…”
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Excess Integrins Cause Lung Entrapment of Mesenchymal Stem Cells by Wang, Shan, Guo, Ling, Ge, Jianfeng, Yu, Lin, Cai, Ting, Tian, Ruiyun, Jiang, Yuyang, Zhao, Robert CH, Wu, Yaojiong

“…Mesenchymal stem cells (MSCs) are largely entrapped in the lungs after intravenous delivery. The underlying mechanisms have been poorly understood. Flow…”
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Identification of human chronic myelogenous leukemia progenitor cells with hemangioblastic characteristics by Fang, Baijun, Zheng, Chunmei, Liao, Lianming, Han, Qin, Sun, Zhao, Jiang, Xueying, Zhao, Robert C.H.

“…Overwhelming evidence from leukemia research has shown that the clonal population of neoplastic cells exhibits marked heterogeneity with respect to…”
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The role of microRNAs in self-renewal and differentiation of mesenchymal stem cells by Guo, Ling, Zhao, Robert C.H, Wu, Yaojiong

“…MicroRNAs (miRNAs) are short non-coding RNAs involved in post-trascriptional regulation of gene expression and diverse biological activities. They are crucial…”
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Effect of O-4-ethoxyl-butyl-berbamine in combination with pegylated liposomal doxorubicin on advanced hepatoma in mice by Fang, Bai-Jun, Yu, Mei-Li, Yang, Shao-Guang, Liao, Lian-Ming, Liu, Jie-Wen, Zhao, Robert C-H

“…AIM: To study the synergistic effects of calmodulin (CAM) antagonist O-4-ethoxyl-butyl-berbamine (EBB) and pegylated liposomal doxorubicin (PLD) on hepatoma-22…”
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Three-dimensional spheroid-cultured mesenchymal stem cells devoid of embolism attenuate brain stroke injury after intra-arterial injection by Guo, Ling, Ge, Jianfeng, Zhou, Ying, Wang, Shan, Zhao, Robert C H, Wu, Yaojiong

“…The therapeutic effect of mesenchymal stem cells (MSCs) in tissue repair/regeneration is substantially dampened by the loss of primitive properties and poor…”
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Enhancer of zeste homolog 2 is overexpressed and contributes to epigenetic inactivation of p21 and phosphatase and tensin homolog in B-cell acute lymphoblastic leukemia by Chen, Jianhe, Li, Jing, Han, Qin, Sun, Zhao, Wang, Jing, Wang, Shihua, Zhao, Robert C H

“…Enhancer of zeste homolog 2 (EZH2) is crucially involved in epigenetic silencing by acting as a histone methyltransferase. Although EZH2 is overexpressed in…”
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Mesenchymal stem cells inhibit Th17 cell differentiation by IL-10 secretion by Qu, Xuebin, Liu, Xingxia, Cheng, Kai, Yang, Rongcun, Zhao, Robert C.H

“…Recent findings indicate that mesenchymal stem cells (MSCs) may act as a regulator of Th17 cell differentiation, however, the underlying mechanism is still…”
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Human adipose tissue−derived mesenchymal stem cells facilitate the immunosuppressive effect of cyclosporin A on T lymphocytes through Jagged-1−mediated inhibition of NF-κB signaling by Shi, Dan, Liao, Lianming, Zhang, Bin, Liu, Rui, Dou, Xiaowei, Li, Jing, Zhu, Xishan, Yu, Limei, Chen, Daixiong, Zhao, Robert C.H

“…Objective Cyclosporine A (CsA), known as an effective immunosuppressive agent, is widely used in clinical fields. Mesenchymal stem cells may exert…”
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miR-21 modulates the ERK-MAPK signaling pathway by regulating SPRY2 expression during human mesenchymal stem cell differentiation by Mei, Yang, Bian, Chunjing, Li, Jing, Du, Zhijian, Zhou, Hong, Yang, Zhuo, Zhao, Robert C.H.

“…The ERK–MAPK signaling pathway plays a pivotal role during mesenchymal stem cell (MSC) differentiation. Studies have demonstrated that ERK–MAPK promotes…”
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Abnormal Integrin-Mediated Regulation of Chronic Myelogenous Leukemia CD34+Cell Proliferation: BCR/ABL Up-Regulates the Cyclin-Dependent Kinase Inhibitor, p27Kip, Which Is Relocated to the Cell Cytoplasm and Incapable of Regulating cdk2 Activity by Jiang, Yuehua, Robert C. H. Zhao, Verfaillie, Catherine M.

“…β1-integrin engagement on normal (NL) CD34+cells increases levels of the cyclin-dependent kinase inhibitor (cdki), p27Kip, decreases cdk2 activity, and…”
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Effects of mesenchymal stem cells on differentiation, maturation, and function of human monocyte-derived dendritic cells by Zhang, Wei, Ge, Wei, Li, Changhong, You, Shengguo, Liao, Lianming, Han, Qin, Deng, Weimin, Zhao, Robert C H

“…Mesenchymal stem cells (MSCs) reportedly inhibit the mixed lymphocyte reaction. Whether this effect is mediated by dendritic cells (DCs) is still unknown. In…”
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Effects of allogeneic bone marrow-derived mesenchymal stem cells on T and B lymphocytes from BXSB mice by Deng, Weimin, Han, Qin, Liao, Lianming, You, Shengguo, Deng, Hongye, Zhao, Robert C H

“…Bone marrow-derived mesenchymal stem cells (bMSCs) can differentiate into a number of different cell/tissue types, and also possess immunoregulatory functions…”
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Intraocular elevation of cyclic AMP potentiates ciliary neurotrophic factor-induced regeneration of adult rat retinal ganglion cell axons by Cui, Q.i, Yip, Henry K, Zhao, Robert C.H, So, Kwok-Fai, Harvey, Alan R

“…In vitro, cyclic AMP (cAMP) elevation alters neuronal responsiveness to diffusible growth factors and myelin-associated inhibitory molecules. Here we used an…”
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