Search Results - "Zhao, Qin‐Shi"

Lycocasine A, a Lycopodium Alkaloid from Lycopodiastrum casuarinoides and Its Acid-Sensing Ion Channel 1a Inhibitory Activity by Jiang, Shuai, Li, Wen-Yan, Gao, Bei-Bei, Zhao, Qin-Shi

“…A novel alkaloid, lycocasine A ( ), and seven known alkaloids ( - ), were isolated from . Their structures were determined through NMR, HRESIMS, and X-ray…”
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The Chemistry and Biology of Lycopodium Alkaloids by Zhang, Zhi‐Jun, Jiang, Shuai, Zhao, Qin‐Shi

“…Lycopodiales, an order comprising 388 distinct species, is the source of Lycopodium alkaloids (LAs), a group of naturally occurring alkaloids that share a…”
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Vibsane‐Type Diterpenoids: Structures, Derivatives, Bioactivities, and Synthesis by Li, Meng, Zhou, Zhi‐Ping, Yuan, Zai‐Feng, Zhao, Qin‐Shi

“…Vibsane‐type diterpenoids isolated from the genus Viburnum, are rare 6–11 membered ring polysubstituted macrocyclic diterpenoids. Since the first report of…”
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Taxodin A, a Cytotoxic C30 Terpenoid from Taxodium mucronatum with a Unique Skeleton by Li, Yao, Zhou, Zhi‐Ping, Chen, Li‐Ting, Zhao, Qin‐Shi

“…Taxodin A (1), a unique C30 terpenoid featuring an unprecedented skeleton composed of an abietane‐type diterpene and a menthane‐type monoterpene, was obtained…”
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Discovery of α‐Obscurine Derivatives as Novel Cav3.1 Calcium Channel Blockers by Wang, Lei, Li, Wen‐Yan, Yuan, Zai‐Feng, Zhao, Qin‐Shi

“…Voltage‐gated calcium channels (VGCCs), particularly T‐type calcium channels (TTCCs), are crucial for various physiological processes and have been implicated…”
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New compound ChlA-F induces autophagy-dependent anti-cancer effect via upregulating Sestrin-2 in human bladder cancer by Hua, Xiaohui, Xu, Jiheng, Deng, Xu, Xu, Jiawei, Li, Jingxia, Zhu, David Q., Zhu, Junlan, Jin, Honglei, Tian, Zhongxian, Huang, Haishan, Zhao, Qin-shi, Huang, Chuanshu

“…ChlA-F is a novel conformation-derivative of Cheliensisin A, styryl-lactone isolates that show potent anti-tumor potential in vivo and vitro. However, the…”
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Alisol B Alleviates Hepatocyte Lipid Accumulation and Lipotoxicity via Regulating RARα-PPARγ-CD36 Cascade and Attenuates Non-Alcoholic Steatohepatitis in Mice by Zhao, Zhuohui, Deng, Zhen-Tao, Huang, Suling, Ning, Mengmeng, Feng, Ying, Shen, Yu, Zhao, Qin-Shi, Leng, Ying

“…Non-alcoholic steatohepatitis (NASH) is a common chronic liver disease worldwide, with no effective therapies available. Discovering lead compounds from herb…”
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Discovery and Biomimetic Semisynthesis of Spirophyllines A–D from Uncaria rhynchophylla by Zhou, Hao-Feng, Li, Wen-Yan, Wu, Qi, Ren, Jian, Peng, Li-Yan, Li, Xiao-Nian, Zhao, Qin-Shi

“…Spirophyllines A–D (1–4), four new spirooxindole alkaloids all characterized by the spiro­[pyrrolidin-3,3′-oxindole] core and a rare isoxazolidine ring, were…”
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Lycopodium Alkaloids from Huperzia goebelii by Gao, Bei‐Bei, Jiang, Shuai, Li, Wen‐Yan, Ou, Yu‐Fei, Zhao, Qin‐Shi

“…One new fawcettimine‐type Lycopodium alkaloid, hupertimine F (1), together with five known (2–6) Lycopodium alkaloids were isolated from Huperzia goebelii. The…”
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The inhibitory effect of compound ChlA-F on human bladder cancer cell invasion can be attributed to its blockage of SOX2 protein by Hua, Xiaohui, Huang, Maowen, Deng, Xu, Xu, Jiheng, Luo, Yisi, Xie, Qipeng, Xu, Jiawei, Tian, Zhongxian, Li, Jingxia, Zhu, Junlan, Huang, Chao, Zhao, Qin-shi, Huang, Haishan, Huang, Chuanshu

“…Sex-determining region Y-box 2 (SOX2), a well-known stemness biomarker, is highly expressed in a variety of cancers, including human highly invasive bladder…”
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Design, Synthesis, and Biological Activities of Vibsanin B Derivatives: A New Class of HSP90 C‑Terminal Inhibitors by Shao, Li-Dong, Su, Jia, Ye, Baixin, Liu, Jiang-Xin, Zuo, Zhi-Li, Li, Yan, Wang, Yue-Ying, Xia, Chengfeng, Zhao, Qin-Shi

“…Previously, vibsanin B (ViB) was found to preferentially target HSP90β compared to HSP90α. In this study, multiple experiments, including pull-down assays of…”
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Hupertimines A–E, Fawcettimine‐Type Lycopodium Alkaloids from Huperzia serrata by Deng, Zhen‐Tao, Liu, Yu‐Chen, Zhu, Qin‐Feng, Jiang, Shuai, Wu, Xing‐De, Zhao, Qin‐Shi

“…Five new fawcettimine‐type Lycopodium alkaloids, hupertimines A–E (1–5), were discovered from the whole plant of Huperzia serrata, along with two known…”
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Hypopurolides A – G, Labdane Diterpenoids from Hypoestes purpurea and Their Nitric Oxide Inhibitory Activity by Ding, Lin‐Fen, Cheng, Bin, Lei, Tie, Liu, Zhen‐Xiang, Zhao, Xue‐Yu, Song, Liu‐Dong, Zhao, Qin‐Shi

“…Seven new labdane diterpenoids, hypopurolides A–G (1–7) were discovered from the aerial part of Hypoestes purpurea, along with one known analog, hypopurin D…”
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seco‐Prezizanne Sesquiterpenes and Prenylated C6‐C3 Compounds from the Fruits of Illicium lanceolatum A. C. Smith by Nie, Wei, Ding, Lin‐Fen, Tie‐Lei, Zhou, Hao‐Feng, Bao, Yi, Song, Liu‐Dong, Pan, Zheng‐Hong, Wu, Xing‐De, Zhao, Qin‐Shi

“…Two new seco‐prezizaane‐type sesquiterpenes, 2β‐hydroxy‐6‐deoxyneoanisatin (1) and 3,4‐anhydro‐2‐oxo‐1α‐hydroxy‐6‐deoxyneoanisatin (2), and two new prenylated…”
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Iridoid Glycosides and Flavonoids Isolated from the Twigs and Leaves of Callicarpa nudiflora and Their Anti‐Inflammatory Activities by Wang, Hao, Dong, Hao‐Yan, Liu, Yan‐Fang, Liang, Ji‐Lei, Liu, Hui‐Sheng, Zhao, Qin‐Shi, Wei, Ping‐He

“…A new iridoid glycoside, named 6′‐O‐trans‐feruloyl‐8‐epiloganic acid, together with fifteen known compounds were isolated from the twigs and leaves of…”
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Guaiane-Type Sesquiterpenoids from Alismatis Rhizoma and Their Anti-inflammatory Activity by Li, Hong-Mei, Fan, Min, Xue, Yong, Peng, Li-Yan, Wu, Xing-De, Liu, Dan, Li, Rong-Tao, Zhao, Qin-Shi

“…Twelve guaiane-type sesquiterpenoids, including four new ones, 10-O-methyl-orientalol A (1), 10-O-ethyl-alismoxide (2), 3β,4β-expoxy-chrysothol (3), orientalol…”
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Neo‐clerodane Diterpenoids with Hypoglycemic Effects in Vivo from the Aerial Parts of Salvia hispanica L by Fan, Min, Wang, Ting, Peng, Li‐Yan, Huang, Jun‐Shang, Wu, Xing‐De, Wang, He‐Yao, Zhao, Qin‐Shi

“…A new neo‐clerodane diterpenoid, salvihispin H (1), and six known ones (2–7) were identified from the aerial parts of Salvia hispanica L. The structure and…”
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Caesalpanins A–C, Three Dimeric Cassane Diterpenoids from the Seeds of Caesalpinia sappan L by Wang, De‐Sheng, Nie, Wei, Jiang, Ting‐Ting, Ding, Lin‐Fen, Song, Liu‐Dong, Wu, Xing‐De, Zhao, Qin‐Shi

“…Three dimeric cassane diterpenoids, caesalpanins A–C, were isolated from the seeds of Caesalpinia sappan L., as well as three known compounds. Their structures…”
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Chemical constituents and biological activities of lycophytes and ferns by ZHU, Qin-Feng, ZHAO, Qin-Shi

“…Lycophytes and ferns are unique and charismatic members of many terrestrial ecosystems and occupy the pivotal position in land plant origin and evolution. The…”
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Activation of SIK1 by phanginin A inhibits hepatic gluconeogenesis by increasing PDE4 activity and suppressing the cAMP signaling pathway by Liu, Siwen, Huang, Suling, Wu, Xingde, Feng, Ying, Shen, Yu, Zhao, Qin-shi, Leng, Ying

“…Salt-induced kinase 1 (SIK1) acts as a key modulator in many physiological processes. However, the effects of SIK1 on gluconeogenesis and the underlying…”
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