Search Results - "Zhao, Michael L"
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Molecular Competition in G1 Controls When Cells Simultaneously Commit to Terminally Differentiate and Exit the Cell Cycle
Published in Cell reports (Cambridge) (16-06-2020)“…Terminal differentiation is essential for the development and maintenance of tissues in all multi-cellular organisms and is associated with permanent exit from…”
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Early enforcement of cell identity by a functional component of the terminally differentiated state
Published in PLoS biology (05-12-2022)“…How progenitor cells can attain a distinct differentiated cell identity is a challenging problem given the fluctuating signaling environment in which cells…”
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3
Expression variation and covariation impair analog and enable binary signaling control
Published in Molecular systems biology (01-05-2018)“…Due to noise in the synthesis and degradation of proteins, the concentrations of individual vertebrate signaling proteins were estimated to vary with a…”
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A Transcriptional Circuit Filters Oscillating Circadian Hormonal Inputs to Regulate Fat Cell Differentiation
Published in Cell metabolism (03-04-2018)“…Glucocorticoid and other adipogenic hormones are secreted in mammals in circadian oscillations. Loss of this circadian oscillation pattern correlates with…”
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5
Nonreciprocal synchronization in embryonic oscillator ensembles
Published in Proceedings of the National Academy of Sciences - PNAS (03-09-2024)“…Synchronization of coupled oscillators is a universal phenomenon encountered across different scales and contexts, e.g., chemical wave patterns,…”
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6
A memory of eS25 loss drives resistance phenotypes
Published in Nucleic acids research (27-07-2020)“…Abstract In order to maintain cellular protein homeostasis, ribosomes are safeguarded against dysregulation by myriad processes. Remarkably, many cell types…”
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A dynamic picture of protein behavior in cells
Published in Nature biotechnology (01-04-2015)“…Protein dynamics in livings cells can now be studied by fully automated, high-throughput fluorescence correlation spectroscopy…”
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8
Nonreciprocal synchronization in embryonic oscillator ensembles
Published in Proceedings of the National Academy of Sciences - PNAS (03-09-2024)“…Synchronization of coupled oscillators is a universal phenomenon encountered across different scales and contexts, e.g., chemical wave patterns,…”
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Journal Article -
9
Early enforcement of cell identity by a functional component of the terminally differentiated state
Published in PLoS biology (01-12-2022)“…How progenitor cells can attain a distinct differentiated cell identity is a challenging problem given the fluctuating signaling environment in which cells…”
Get full text
Journal Article