Search Results - "Zhao, Grace Q"

Single-cell transcriptomes and whole-brain projections of serotonin neurons in the mouse dorsal and median raphe nuclei by Ren, Jing, Isakova, Alina, Friedmann, Drew, Zeng, Jiawei, Grutzner, Sophie M, Pun, Albert, Zhao, Grace Q, Kolluru, Sai Saroja, Wang, Ruiyu, Lin, Rui, Li, Pengcheng, Li, Anan, Raymond, Jennifer L, Luo, Qingming, Luo, Minmin, Quake, Stephen R, Luo, Liqun

“…Serotonin neurons of the dorsal and median raphe nuclei (DR, MR) collectively innervate the entire forebrain and midbrain, modulating diverse physiology and…”
Get full text

Cross-Platform Comparison of Four Leading Technologies for Detecting EGFR Mutations in Circulating Tumor DNA from Non-Small Cell Lung Carcinoma Patient Plasma by Xu, Ting, Kang, Xiaozheng, You, Xiaofang, Dai, Liang, Tian, Dequan, Yan, Wanpu, Yang, Yongbo, Xiong, Hongchao, Liang, Zhen, Zhao, Grace Q, Lin, Shengrong, Chen, Ke-Neng, Xu, Guobing

“…Analysis of circulating tumor DNA (ctDNA) is emerging as a powerful tool for guiding targeted therapy and monitoring tumor evolution in patients with non-small…”
Get full text

The Receptors for Mammalian Sweet and Umami Taste by Zhao, Grace Q., Zhang, Yifeng, Hoon, Mark A., Chandrashekar, Jayaram, Erlenbach, Isolde, Ryba, Nicholas J.P., Zuker, Charles S.

“…Sweet and umami (the taste of monosodium glutamate) are the main attractive taste modalities in humans. T1Rs are candidate mammalian taste receptors that…”
Get full text

A saturation hypothesis to explain both enhanced and impaired learning with enhanced plasticity by Nguyen-Vu, Td Barbara, Zhao, Grace Q, Lahiri, Subhaneil, Kimpo, Rhea R, Lee, Hanmi, Ganguli, Surya, Shatz, Carla J, Raymond, Jennifer L

“…Across many studies, animals with enhanced synaptic plasticity exhibit enhanced or impaired learning, raising a conceptual puzzle: how enhanced plasticity can…”
Get full text

Evolution of Network Synchronization during Early Epileptogenesis Parallels Synaptic Circuit Alterations by Lillis, Kyle P, Wang, Zemin, Mail, Michelle, Zhao, Grace Q, Berdichevsky, Yevgeny, Bacskai, Brian, Staley, Kevin J

“…In secondary epilepsy, a seizure-prone neural network evolves during the latent period between brain injury and the onset of spontaneous seizures. The nature…”
Get full text

Signals and learning rules guiding oculomotor plasticity by Shin, Soon-Lim, Zhao, Grace Q, Raymond, Jennifer L

“…The learning of motor skills is thought to occur largely through trial and error; however, the error signals and rules controlling the induction of motor…”
Get full text

A novel NGS kit solution for multi-cancer early detection using circulating cell free DNA based methylation analysis by Zhao, Grace Q., Bao, Yun, Wang, Heng, Vu, Peter, Patel, Sandip Pravin, Lin, Shengrong

“…10542 Background: Cancer patient survival can be greatly improved by early detection. Cell-free DNA (cfDNA)-based cancer detection using targeted methylation…”
Get full text

A dual target sequencing solution to assess genomic and epigenomic alterations in cell-free DNA with no sample splitting by Zhao, Grace Q., Bao, Yun, Wang, Heng, Hu, Wanping, Coller, John, Lin, Shengrong

“…Abstract only 3043 Background: Assessing the genomic and epigenomic changes on plasma cell-free DNA (cfDNA) using next-generation sequencing (NGS) has become…”
Get full text

The development and validation of a novel targeted methylation sequencing technology detecting 0.003 percent tumor signal in early-stage cancer plasma by Zhao, Grace Q., Bao, Yun, Wang, Heng, Wang, Jianmin, Lin, Shengrong

“…Abstract only 4092 Background: Methylation analysis in cell-free DNA holds great potential for early cancer detection. In the plasma of early stage cancer…”
Get full text

Abstract LB059: Dual methylation and mutation analysis from a single input of plasma cfDNA without sample splitting by Zhao, Grace Q., Bao, Yun, Wang, Heng, Natu, Vanita S., Joshi, Jayashree, Wang, Yingmin, Arzumanyan, Elena, Wang, Wanping, Wang, Jianmin, Coller, John, Lin, Shengrong

“…Abstract Genomic and epigenetic changes are known to be the underlying mechanism of cancer development. Assessing the genomic (mutation) and epigenetic…”
Get full text

Abstract 259: Fully automated targeted sequencing sample prep on open platform liquid handlers by Wahba, Ashraf, Bao, Yun, Wang, Heng, Watson, Kinnari, Zhao, Grace Q., Lin, Shengrong

“…Abstract To accommodate the growing demands of sample throughput, reliability, and reduced hands-on time of targeted sequencing, automation is critical. The…”
Get full text

Predicting long-term prognosis using targeted cell free DNA sequencing in resectable pancreatic cancer patients by Song, Bo, Tang, Ling Fung Paul, Zhao, Grace Q., Lin, Shengrong, Ying, Kang, Jin, Gang

“…Abstract only…”
Get full text

Predictive value of circulating tumor DNA in locally advanced rectal cancer patients receiving neoadjuvant radiochemotherapy by Li, Min, Xiao, WeiWei, Zhao, Grace Q., Guo, Zhiwei, Yang, Xuexi, Lin, Shengrong, Ying, Kang, Li, Ming, Gao, Yuan-Hong

“…Abstract only e15125 Background: Neoadjuvant radiochemotherapy (RCT) is rapidly becoming the preferred treatment for patients diagnosed with late-stage locally…”
Get full text

Abstract 938: Detection of actionable mutations in plasma cfDNA samples from patients with non-small cell lung carcinoma using a novel amplicon-based Firefly NGS assay by Wang, Lin, Weng, Li, Chen, Xiao, Li, Min, Guo, Qiaomei, Yu, Wenjun, Wittkop, Tobias, Wang, Hongyan, Fahem, Malek, Lin, Shengrong, Zhao, Grace Q., Lou, Jiatao

“…Abstract Background: Detection of EGFR, KRAS and BRAF mutations can help guide cancer treatment for non-small cell lung cancer (NSCLC) patients. To identify an…”
Get full text

Abstract B071: Detecting ultra low-frequency variants and fusions using a novel amplicon-based Accu-CometTM method by Wang, Ling, Zhao, Grace Q., Weng, Li, Chen, Xiao, Li, Min, Yang, Xue, Zhao, Jun, Wang, Hongyan, Ying, Kang, Faham, Malek, Lin, Shengrong, Lou, Jiatao

“…Abstract We report the development of an ultra-accurate NGS technology, Accu-CometTM, which employs a concatemer-based error correction with amplicon workflow…”
Get full text

Abstract 2742: Cross-platform comparison of four leading technologies for detecting EGFR mutations in circulating tumor DNA from plasma of patients with non-small cell lung carcinoma by Xu, Ting, Kang, Xiaozheng, You, Xiaofang, Liang, Dai, Tian, Dequan, Yan, Wanpu, Yang, Yongbo, Xiong, Hongchao, Liang, Zhen, Zhao, Grace Q., Lin, Shengrong, Chen, Ke-Neng, Xu, Guobing

“…Abstract Analysis of circulating tumor DNA (ctDNA) is emerging as a powerful tool for guiding targeted therapy and monitoring tumor evolution in patients with…”
Get full text

Comparative analysis of the representative value of somatic mutation profiles derived from ctDNA and other updated lung tumor biopsy alternative in non-resectable non-small cell lung cancer patients by Kang, Xiaozheng, Xu, Ting, Zhou, Ting, Tian, De-Qun, Zhao, Grace Q., Lin, Shengrong, Ying, Kang, Xu, Guo-Bing, Chen, Ke-Neng

“…Abstract only…”
Get full text

Retrospective analysis of circulating tumor DNA of archived plasma samples by Shen, Wei, Zhao, Grace Q., Liang, Zhonglin, Yellapantula, Venkata, Sun, Sam, Tang, Ling Fung Paul, Lin, Shengrong, Ying, Kang, Fields, Ryan C., Ding, Li

“…Abstract only…”
Get full text

Accuracy of profiling of circulating tumor DNA for CRC MRD and monitoring using NGS technology equipped with concatemer-based error correction by Zhao, Grace Q., Weng, Li, Li, Xin-Xing, Li, Min, Tang, Paul, Lu, Yontao, Wang, Yingyu, Huang, Yi, Wang, Hongyan, Guo, Lingchen, Yeo, Dana, Sun, Zhaohui Johnny, Xiao, WeiWei, Hu, Zhi-Qian, Li, Ming, Ying, Kang, Faham, Malek, Lin, Shengrong

“…Abstract only e23067 Background: Circulating tumor DNA (ctDNA) is a promising biomarker for the detection of minimal residual disease and monitoring treatment…”
Get full text

Detecting ultra low-frequency variants and gene fusions in lung cancer patients using an amplicon-based Firefly NGS method by Weng, Li, Wang, Lin, Chen, Xiao, Zhang, Jacey, Lin, Chiahui, Wang, Yingyu, Brice, Tim, Huang, Yi, Wang, Hongyan, Tang, Paul, Sun, Zhaohui Johnny, Zhao, Grace Q., Lou, Jiatao, Ying, Kang, Faham, Malek, Lin, Shengrong

“…Abstract only e23062 Background: The analysis of EGFR, KRAS, and BRAF mutations and Alk fusion is critical for guiding targeted therapy selection, detecting…”
Get full text