Search Results - "Zhao, Fangqing"

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  1. 1

    Accurate quantification of circular RNAs identifies extensive circular isoform switching events by Zhang, Jinyang, Chen, Shuai, Yang, Jingwen, Zhao, Fangqing

    Published in Nature communications (03-01-2020)
    “…Detection and quantification of circular RNAs (circRNAs) face several significant challenges, including high false discovery rate, uneven rRNA depletion and…”
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  2. 2

    CircAtlas: an integrated resource of one million highly accurate circular RNAs from 1070 vertebrate transcriptomes by Wu, Wanying, Ji, Peifeng, Zhao, Fangqing

    Published in Genome Biology (28-04-2020)
    “…Existing circular RNA (circRNA) databases have become essential for transcriptomics. However, most are unsuitable for mining in-depth information for candidate…”
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  3. 3

    Circular RNA identification based on multiple seed matching by Gao, Yuan, Zhang, Jinyang, Zhao, Fangqing

    Published in Briefings in bioinformatics (28-09-2018)
    “…Abstract Computational detection methods have been widely used in studies on the biogenesis and the function of circular RNAs (circRNAs). However, all of the…”
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  4. 4

    CIRI: an efficient and unbiased algorithm for de novo circular RNA identification by Gao, Yuan, Wang, Jinfeng, Zhao, Fangqing

    Published in Genome Biology (13-01-2015)
    “…Recent studies reveal that circular RNAs (circRNAs) are a novel class of abundant, stable and ubiquitous noncoding RNA molecules in animals. Comprehensive…”
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  5. 5

    Deterministic transition of enterotypes shapes the infant gut microbiome at an early age by Xiao, Liwen, Wang, Jinfeng, Zheng, Jiayong, Li, Xiaoqing, Zhao, Fangqing

    Published in Genome Biology (24-08-2021)
    “…The succession of the gut microbiota during the first few years plays a vital role in human development. We elucidate the characteristics and alternations of…”
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  6. 6

    Translocation of vaginal microbiota is involved in impairment and protection of uterine health by Wang, Jinfeng, Li, Zhanzhan, Ma, Xiuling, Du, Lifeng, Jia, Zhen, Cui, Xue, Yu, Liqun, Yang, Jing, Xiao, Liwen, Zhang, Bing, Fan, Huimin, Zhao, Fangqing

    Published in Nature communications (07-07-2021)
    “…The vaginal and uterine microbiota play important roles in the health of the female reproductive system. However, the interactions among the microbes in these…”
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  7. 7

    Comprehensive identification of internal structure and alternative splicing events in circular RNAs by Gao, Yuan, Wang, Jinfeng, Zheng, Yi, Zhang, Jinyang, Chen, Shuai, Zhao, Fangqing

    Published in Nature communications (28-06-2016)
    “…Although previous studies demonstrated circular RNAs (circRNAs) does not exclusively comprise mRNA exons, no study has extensively explored their internal…”
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  8. 8

    Changes to gut amino acid transporters and microbiome associated with increased E/I ratio in Chd8+/− mouse model of ASD-like behavior by Yu, You, Zhang, Bing, Ji, Peifeng, Zuo, Zhenqiang, Huang, Yongxi, Wang, Ning, Liu, Chang, Liu, Shuang-Jiang, Zhao, Fangqing

    Published in Nature communications (03-03-2022)
    “…Autism spectrum disorder (ASD), a group of neurodevelopmental disorders characterized by social communication deficits and stereotyped behaviors, may be…”
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  9. 9

    Single-cell metagenomics: challenges and applications by Xu, Yuan, Zhao, Fangqing

    Published in Protein & cell (01-05-2018)
    “…With the development of high throughput sequencing and single-cell genomics technologies, many uncultured bacterial communities have been dissected by…”
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  10. 10

    Reconstruction of full-length circular RNAs enables isoform-level quantification by Zheng, Yi, Ji, Peifeng, Chen, Shuai, Hou, Lingling, Zhao, Fangqing

    Published in Genome medicine (19-01-2019)
    “…Currently, circRNA studies are shifting from the identification of circular transcripts to understanding their biological functions. However, such endeavors…”
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  11. 11

    Phage-bacteria interaction network in human oral microbiome by Wang, Jinfeng, Gao, Yuan, Zhao, Fangqing

    Published in Environmental microbiology (01-07-2016)
    “…Summary Although increasing knowledge suggests that bacteriophages play important roles in regulating microbial ecosystems, phage–bacteria interaction in human…”
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  12. 12

    Exploring the cellular landscape of circular RNAs using full-length single-cell RNA sequencing by Wu, Wanying, Zhang, Jinyang, Cao, Xiaofei, Cai, Zhengyi, Zhao, Fangqing

    Published in Nature communications (10-06-2022)
    “…Previous studies have demonstrated the highly specific expression of circular RNAs (circRNAs) in different tissues and organisms, but the cellular architecture…”
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  13. 13

    MetaSort untangles metagenome assembly by reducing microbial community complexity by Ji, Peifeng, Zhang, Yanming, Wang, Jinfeng, Zhao, Fangqing

    Published in Nature communications (23-01-2017)
    “…Most current approaches to analyse metagenomic data rely on reference genomes. Novel microbial communities extend far beyond the coverage of reference…”
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  14. 14
  15. 15

    Convergent Evolution of Rumen Microbiomes in High-Altitude Mammals by Zhang, Zhigang, Xu, Dongming, Wang, Li, Hao, Junjun, Wang, Jinfeng, Zhou, Xin, Wang, Weiwei, Qiu, Qiang, Huang, Xiaodan, Zhou, Jianwei, Long, Ruijun, Zhao, Fangqing, Shi, Peng

    Published in Current biology (25-07-2016)
    “…Studies of genetic adaptation, a central focus of evolutionary biology, most often focus on the host’s genome and only rarely on its co-evolved microbiome. The…”
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  16. 16

    Genomic insights into the cellular specialization of predation in raptorial protists by Li, Zaihan, Chen, Xiao, Zhao, Fangqing, Miao, Miao

    Published in BMC biology (07-05-2024)
    “…Predation is a fundamental mechanism for organisms to acquire energy, and various species have evolved diverse tools to enhance their hunting abilities. Among…”
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  17. 17

    Prioritization and functional assessment of noncoding variants associated with complex diseases by Zhou, Lin, Zhao, Fangqing

    Published in Genome medicine (11-07-2018)
    “…Unraveling functional noncoding variants associated with complex diseases is still a great challenge. We present a novel algorithm, Prioritization And…”
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  18. 18

    Expanded Expression Landscape and Prioritization of Circular RNAs in Mammals by Ji, Peifeng, Wu, Wanying, Chen, Shuai, Zheng, Yi, Zhou, Lin, Zhang, Jinyang, Cheng, Hao, Yan, Jin, Zhang, Shaogeng, Yang, Penghui, Zhao, Fangqing

    Published in Cell reports (Cambridge) (19-03-2019)
    “…Circular RNAs (circRNAs) are emerging as essential regulators of various biological and disease processes. To comprehensively understand the diversity of…”
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  19. 19

    Gut microbiota dysbiosis contributes to the development of hypertension by Li, Jing, Zhao, Fangqing, Wang, Yidan, Chen, Junru, Tao, Jie, Tian, Gang, Wu, Shouling, Liu, Wenbin, Cui, Qinghua, Geng, Bin, Zhang, Weili, Weldon, Ryan, Auguste, Kelda, Yang, Lei, Liu, Xiaoyan, Chen, Li, Yang, Xinchun, Zhu, Baoli, Cai, Jun

    Published in Microbiome (01-02-2017)
    “…Recently, the potential role of gut microbiome in metabolic diseases has been revealed, especially in cardiovascular diseases. Hypertension is one of the most…”
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  20. 20

    HTQC: a fast quality control toolkit for Illumina sequencing data by Yang, Xi, Liu, Di, Liu, Fei, Wu, Jun, Zou, Jing, Xiao, Xue, Zhao, Fangqing, Zhu, Baoli

    Published in BMC bioinformatics (31-01-2013)
    “…Illumina sequencing platform is widely used in genome research. Sequence reads quality assessment and control are needed for downstream analysis. However,…”
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