Search Results - "Zhao, Dengshuai"
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ZBP1: A Powerful Innate Immune Sensor and Double-Edged Sword in Host Immunity
Published in International journal of molecular sciences (06-09-2022)“…Z-conformation nucleic acid binding protein 1 (ZBP1), a powerful innate immune sensor, has been identified as the important signaling initiation factor in…”
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Mechanism of interaction between virus and host is inferred from the changes of gene expression in macrophages infected with African swine fever virus CN/GS/2018 strain
Published in Virology journal (19-08-2021)“…African swine fever virus (ASFV) is a highly lethal virus that can infect porcine alveolar macrophages (PAMs). Since ASFV, China has dealt with a heavy blow to…”
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ASFV infection induces macrophage necroptosis and releases proinflammatory cytokine by ZBP1-RIPK3-MLKL necrosome activation
Published in Frontiers in microbiology (17-06-2024)“…African swine fever (ASF) is an infectious disease characterized by hemorrhagic fever, which is highly pathogenic and causes severe mortality in domestic pigs…”
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DDX20: A Multifunctional Complex Protein
Published in Molecules (Basel, Switzerland) (01-10-2023)“…DEAD-box decapping enzyme 20 (DDX20) is a putative RNA-decapping enzyme that can be identified by the conserved motif Asp–Glu–Ala–Asp (DEAD). Cellular…”
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First report on the identification and characterization of mammalian orthoreovirus from sheep in China
Published in Microbiology spectrum (15-10-2024)Get full text
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African swine fever virus MGF360-9L promotes viral replication by degrading the host protein HAX1
Published in Virus research (15-10-2023)“…•Mechanism of HAX1 regulates ASFV replication through interactions with MGF360–9 L.•Key regions of interaction between ASFV MGF360–9 L & HAX1 were predicted &…”
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Annexin A2: A Double-Edged Sword in Pathogen Infection
Published in Pathogens (Basel) (04-07-2024)“…Annexin A2 (ANXA2) is a multifunctional calcium- and phospholipid-binding protein that plays an important role in various cells. During pathogen infections,…”
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Identification and analysis of the interaction network of African swine fever virus D1133L with host proteins
Published in Frontiers in microbiology (03-11-2022)“…African swine fever (ASF) is a contagious and lethal hemorrhagic disease in pigs; its spread results in huge economic losses to the global pig industry. ASF…”
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Profiling and functional analysis of differentially expressed circular RNAs identified in foot-and-mouth disease virus infected PK-15 cells
Published in Veterinary research (Paris) (21-03-2022)“…Circular RNAs (circRNAs) are a new type of endogenous noncoding RNA that exhibit a variety of biological functions. However, it is not clear whether they are…”
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Construction, Identification and Analysis of the Interaction Network of African Swine Fever Virus MGF360-9L with Host Proteins
Published in Viruses (10-09-2021)“…African swine fever virus (ASFV) is prevalent in many countries and is a contagious and lethal virus that infects pigs, posing a threat to the global pig…”
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Advanced Research in Porcine Reproductive and Respiratory Syndrome Virus Co-infection With Other Pathogens in Swine
Published in Frontiers in veterinary science (26-08-2021)“…The porcine reproductive and respiratory syndrome virus (PRRSV) is the pathogen causing epidemics of porcine reproductive and respiratory syndrome (PRRS), and…”
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Functional Analysis and Proteomics Profiling of Extracellular Vesicles From Swine Plasma Infected by African Swine Fever Virus
Published in Frontiers in cellular and infection microbiology (10-02-2022)“…African swine fever (ASF) has brought excellent barriers to swine production in China and the world. Studies have shown that extracellular vesicles mediate the…”
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Identification and verification of the role of key metabolites and metabolic pathways on ASFV replication
Published in iScience (19-04-2024)“…African swine fever virus (ASFV) infection usually causes viremia within a few days. However, the metabolic changes in pig serum after ASFV infection remain…”
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Component Identification and Analysis of Vesicular Fluid From Swine Infected by Foot-and-Mouth Disease Virus
Published in Frontiers in veterinary science (17-03-2022)“…Foot-and-mouth disease (FMD) is induced by FMD virus (FMDV) and characterized by fever and vesicular (blister-like) lesions. However, the exact composition of…”
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Isolation and Genomic Characterization of the G6P[1]‐Type Sheep Rotavirus in China
Published in Transboundary and emerging diseases (01-01-2024)“…Rotavirus A (RVA) is a prevalent cause of enteric diarrhea in infants, bovine, pigs, and sheep globally. Currently, the G6P[1]‐type rotaviruses are prevalent…”
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Molecular functions of HAX1 during disease progress
Published in Virus genes (01-10-2024)“…HCLS1-associated protein X-1 (HAX1) is a newly discovered multifunctional cell regulatory protein that is widely expressed in cells and has a close…”
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PI3K–Akt pathway-independent PIK3AP1 identified as a replication inhibitor of the African swine fever virus based on iTRAQ proteomic analysis
Published in Virus research (02-04-2023)“…•Using the isobaric tags for relative and absolute quantitation combined with liquid chromatography-mass spectrometry, 286 upregulated differentially expressed…”
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Metabolomic analysis of pig spleen reveals African swine fever virus infection increased acylcarnitine levels to facilitate viral replication
Published in Journal of virology (31-08-2023)“…African swine fever (ASF) is a devastating disease caused by the African swine fever virus (ASFV) that adversely affects the pig industry. The spleen is the…”
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Cyproheptadine hydrochloride inhibits African swine fever viral replication in vitro
Published in Microbial pathogenesis (01-02-2023)“…African swine fever (ASF) is an infectious disease caused by the African swine fever virus (ASFV), and has a high mortality rate. It has caused serious…”
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