Search Results - "Zhao, David X. M."

Effect of Transendocardial Delivery of Autologous Bone Marrow Mononuclear Cells on Functional Capacity, Left Ventricular Function, and Perfusion in Chronic Heart Failure: The FOCUS-CCTRN Trial by Perin, Emerson C, Willerson, James T, Pepine, Carl J, Henry, Timothy D, Ellis, Stephen G, Zhao, David X. M, Silva, Guilherme V, Lai, Dejian, Thomas, James D, Kronenberg, Marvin W, Martin, A. Daniel, Anderson, R. David, Traverse, Jay H, Penn, Marc S, Anwaruddin, Saif, Hatzopoulos, Antonis K, Gee, Adrian P, Taylor, Doris A, Cogle, Christopher R, Smith, Deirdre, Westbrook, Lynette, Chen, James, Handberg, Eileen, Olson, Rachel E, Geither, Carrie, Bowman, Sherry, Francescon, Judy, Baraniuk, Sarah, Piller, Linda B, Simpson, Lara M, Loghin, Catalin, Aguilar, David, Richman, Sara, Zierold, Claudia, Bettencourt, Judy, Sayre, Shelly L, Vojvodic, Rachel W, Skarlatos, Sonia I, Gordon, David J, Ebert, Ray F, Kwak, Minjung, Moyé, Lemuel A, Simari, Robert D

“…CONTEXT: Previous studies using autologous bone marrow mononuclear cells (BMCs) in patients with ischemic cardiomyopathy have demonstrated safety and suggested…”
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Identification of Bone Marrow Cell Subpopulations Associated With Improved Functional Outcomes in Patients With Chronic Left Ventricular Dysfunction: An Embedded Cohort Evaluation of the FOCUS-CCTRN Trial by Taylor, Doris A, Perin, Emerson C, Willerson, James T, Zierold, Claudia, Resende, Micheline, Carlson, Marjorie, Nestor, Belinda, Wise, Elizabeth, Orozco, Aaron, Pepine, Carl J, Henry, Timothy D, Ellis, Stephen G, Zhao, David X M, Traverse, Jay H, Cooke, John P, Schutt, Robert C, Bhatnagar, Aruni, Grant, Maria B, Lai, Dejian, Johnstone, Brian H, Sayre, Shelly L, Moyé, Lem, Ebert, Ray F, Bolli, Roberto, Simari, Robert D, Cogle, Christopher R

“…In the current study, we sought to identify bone marrow-derived mononuclear cell (BM-MNC) subpopulations associated with a combined improvement in left…”
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Effect of the Use and Timing of Bone Marrow Mononuclear Cell Delivery on Left Ventricular Function After Acute Myocardial Infarction: The TIME Randomized Trial by Traverse, Jay H, Henry, Timothy D, Pepine, Carl J, Willerson, James T, Zhao, David X. M, Ellis, Stephen G, Forder, John R, Anderson, R. David, Hatzopoulos, Antonis K, Penn, Marc S, Perin, Emerson C, Chambers, Jeffrey, Baran, Kenneth W, Raveendran, Ganesh, Lambert, Charles, Lerman, Amir, Simon, Daniel I, Vaughan, Douglas E, Lai, Dejian, Gee, Adrian P, Taylor, Doris A, Cogle, Christopher R, Thomas, James D, Olson, Rachel E, Bowman, Sherry, Francescon, Judy, Geither, Carrie, Handberg, Eileen, Kappenman, Casey, Westbrook, Lynette, Piller, Linda B, Simpson, Lara M, Baraniuk, Sarah, Loghin, Catalin, Aguilar, David, Richman, Sara, Zierold, Claudia, Spoon, Daniel B, Bettencourt, Judy, Sayre, Shelly L, Vojvodic, Rachel W, Skarlatos, Sonia I, Gordon, David J, Ebert, Ray F, Kwak, Minjung, Moyé, Lemuel A, Simari, Robert D

“…CONTEXT While the delivery of cell therapy after ST-segment elevation myocardial infarction (STEMI) has been evaluated in previous clinical trials, the…”
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Effect of Intracoronary Delivery of Autologous Bone Marrow Mononuclear Cells 2 to 3 Weeks Following Acute Myocardial Infarction on Left Ventricular Function: The LateTIME Randomized Trial by Traverse, Jay H, Henry, Timothy D, Ellis, Stephen G, Pepine, Carl J, Willerson, James T, Zhao, David X. M, Forder, John R, Byrne, Barry J, Hatzopoulos, Antonis K, Penn, Marc S, Perin, Emerson C, Baran, Kenneth W, Chambers, Jeffrey, Lambert, Charles, Raveendran, Ganesh, Simon, Daniel I, Vaughan, Douglas E, Simpson, Lara M, Gee, Adrian P, Taylor, Doris A, Cogle, Christopher R, Thomas, James D, Silva, Guilherme V, Jorgenson, Beth C, Olson, Rachel E, Bowman, Sherry, Francescon, Judy, Geither, Carrie, Handberg, Eileen, Smith, Deirdre X, Baraniuk, Sarah, Piller, Linda B, Loghin, Catalin, Aguilar, David, Richman, Sara, Zierold, Claudia, Bettencourt, Judy, Sayre, Shelly L, Vojvodic, Rachel W, Skarlatos, Sonia I, Gordon, David J, Ebert, Ray F, Kwak, Minjung, Moyé, Lemuel A, Simari, Robert D, Cardiovascular Cell Therapy ResearchNetwork (CCTRN), for the

“…CONTEXT Clinical trial results suggest that intracoronary delivery of autologous bone marrow mononuclear cells (BMCs) may improve left ventricular (LV)…”
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Rationale and design for TIME: A phase II, randomized, double-blind, placebo-controlled pilot trial evaluating the safety and effect of timing of administration of bone marrow mononuclear cells after acute myocardial infarction by Traverse, Jay H., MD, Henry, Timothy D., MD, Vaughn, Douglas E., MD, Ellis, Stephen G., MD, Pepine, Carl J., MD, Willerson, James T., MD, Zhao, David X.M., MD, Piller, Linda B., MD, Penn, Marc S., MD, PhD, Byrne, Barry J., MD, Perin, Emerson C., MD, PhD, Gee, Adrian P., MD, Hatzopoulos, Antonis K., MD. PhD, McKenna, David H., MD, Forder, John R., MD, Taylor, Doris A., PhD, Cogle, Christopher R., MD, Olson, Rachel E., RN, Jorgenson, Beth C., RN, Sayre, Shelly L., MPH, Vojvodic, Rachel W., MPH, Gordon, David J., PhD, Skarlatos, Sonia I., PhD, Moye', Lemuel A., MD, PhD, Simari, Robert D., MD

“…Several previous studies have demonstrated that administration of autologous bone marrow–derived mononuclear cells (BMMNCs) improves cardiac function in…”
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A novel technique for postclosure of large‐bore sheaths using two Perclose devices by Choi, Charles H., Hall, James Kevin, Malaver, Diego, Applegate, Robert J., Zhao, David X. M.

“…Objectives This study aimed to assess the feasibility, efficacy, and safety of a novel percutaneous postprocedure closure technique for large arterial sheath…”
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Intramyocardial injection of autologous bone marrow mononuclear cells for patients with chronic ischemic heart disease and left ventricular dysfunction ( F irst M o nonuclear C ells injected in the US [FOCUS]): Rationale and design by Willerson, James T., MD, Perin, Emerson C., MD, Ellis, Stephen G., MD, Pepine, Carl J., MD, Henry, Timothy D., MD, Zhao, David X.M., MD, Lai, Dejian, PhD, Penn, Marc S., MD, PhD, Byrne, Barry J., MD, Silva, Guilherme, MD, Gee, Adrian, MD, Traverse, Jay H., MD, Hatzopoulos, Antonis K., MD, PhD, Forder, John R., MD, Martin, Daniel, MD, Kronenberg, Marvin, MD, Taylor, Doris A., PhD, Cogle, Christopher R., MD, Baraniuk, Sarah, PhD, Westbrook, Lynette, RN, Sayre, Shelly L., MPH, Vojvodic, Rachel W., MPH, Gordon, David J., PhD, Skarlatos, Sonia I., PhD, Moyé, Lemuel A., MD, PhD, Simari, Robert D., MD

“…Background The increasing worldwide prevalence of coronary artery disease (CAD) continues to challenge the medical community. Management options include…”
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Comparison of paravalvular aortic leak characteristics in the Medtronic CoreValve versus Edwards Sapien Valve: Paravalvular aortic leak characteristics by Gilbert, Olivia N., Choi, Charles H., Franzil, Jodie L., Caughey, Melissa, Qureshi, Waqas, Stacey, R. Brandon, Pu, Min, Applegate, Robert J., Gandhi, Sanjay K., Zhao, David X. M.

“…Objectives Temporally quantify and localize paravalvular aortic leak (PVL) after transcatheter aortic valve replacement (TAVR) in the Medtronic CoreValve (MCV)…”
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Bone marrow cell characteristics associated with patient profile and cardiac performance outcomes in the LateTIME-Cardiovascular Cell Therapy Research Network (CCTRN) trial by Bhatnagar, Aruni, Bolli, Roberto, Johnstone, Brian H., Traverse, Jay H., Henry, Timothy D., Pepine, Carl J., Willerson, James T., Perin, Emerson C., Ellis, Stephen G., Zhao, David X.M., Yang, Phillip C., Cooke, John P., Schutt, Robert C., Trachtenberg, Barry H., Orozco, Aaron, Resende, Micheline, Ebert, Ray F., Sayre, Shelly L., Simari, Robert D., Moyé, Lem, Cogle, Christopher R., Taylor, Doris A.

“…Although several preclinical studies have shown that bone marrow cell (BMC) transplantation promotes cardiac recovery after myocardial infarction, clinical…”
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TIME Trial: Effect of Timing of Stem Cell Delivery Following ST-Elevation Myocardial Infarction on the Recovery of Global and Regional Left Ventricular Function: Final 2-Year Analysis by Traverse, Jay H, Henry, Timothy D, Pepine, Carl J, Willerson, James T, Chugh, Atul, Yang, Phillip C, Zhao, David X.M, Ellis, Stephen G, Forder, John R, Perin, Emerson C, Penn, Marc S, Hatzopoulos, Antonis K, Chambers, Jeffrey C, Baran, Kenneth W, Raveendran, Ganesh, Gee, Adrian P, Taylor, Doris A, Moyé, Lem, Ebert, Ray F, Simari, Robert D

“…RATIONALE:The TIME trial (Timing in Myocardial Infarction Evaluation) was the first cell therapy trial sufficiently powered to determine if timing of cell…”
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A comparison of valve‐in‐valve transcatheter aortic valve replacement in failed stentless versus stented surgical bioprosthetic aortic valves by Choi, Charles H., Cheng, Vivian, Malaver, Diego, Kon, Neal, Kincaid, Edward H., Gandhi, Sanjay K., Applegate, Robert J., Zhao, David X. M.

“…Objectives The objectives of this study were to compare short‐ and intermediate‐term clinical outcomes, procedural complications, TAVR prosthesis hemodynamics,…”
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Redo‐aortic valve replacement in prior stentless prosthetic aortic valves: Transcatheter versus surgical approach by Choi, Charles H., Cao, Kevin, Malaver, Diego, Kincaid, Edward H., Lata, Adrian, Kon, Neal, Belford, P. Matthew, Gandhi, Sanjay K., Applegate, Robert J., Zhao, David X. M.

“…Objectives The objective was to compare outcomes of redo‐aortic valve replacement (AVR) via surgical or transcatheter approach in prior surgical AVR with large…”
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Treatment of Unprotected Left Main Coronary Artery Stenosis in a 5-Year-Old Heart Transplant Patient Using a Sirolimus-Eluting Stent by Salloum, Joseph G., MD, Dodd, Debra A., MD, Slosky, David, MD, Zhao, David X.M., MD

“…Cardiac allograft vasculopathy is the most common cause of long-term graft failure in adult and pediatric heart transplant recipients. In the absence of a…”
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Detailed Analysis of Bone Marrow From Patients With Ischemic Heart Disease and Left Ventricular Dysfunction: BM CD34, CD11b, and Clonogenic Capacity as Biomarkers for Clinical Outcomes by Cogle, Christopher R, Wise, Elizabeth, Meacham, Amy M, Zierold, Claudia, Traverse, Jay H, Henry, Timothy D, Perin, Emerson C, Willerson, James T, Ellis, Stephen G, Carlson, Marjorie, Zhao, David X.M, Bolli, Roberto, Cooke, John P, Anwaruddin, Saif, Bhatnagar, Aruni, da Graca Cabreira-Hansen, Maria, Grant, Maria B, Lai, Dejian, Moyé, Lem, Ebert, Ray F, Olson, Rachel E, Sayre, Shelly L, Schulman, Ivonne H, Bosse, Raphael C, Scott, Edward W, Simari, Robert D, Pepine, Carl J, Taylor, Doris A

“…RATIONALE:Bone marrow (BM) cell therapy for ischemic heart disease (IHD) has shown mixed results. Before the full potency of BM cell therapy can be realized,…”
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Bone Marrow Characteristics Associated With Changes in Infarct Size After STEMI: A Biorepository Evaluation From the CCTRN TIME Trial by Schutt, Robert C, Trachtenberg, Barry H, Cooke, John P, Traverse, Jay H, Henry, Timothy D, Pepine, Carl J, Willerson, James T, Perin, Emerson C, Ellis, Stephen G, Zhao, David X.M, Bhatnagar, Aruni, Johnstone, Brian H, Lai, Dejian, Resende, Micheline, Ebert, Ray F, Wu, Joseph C, Sayre, Shelly L, Orozco, Aaron, Zierold, Claudia, Simari, Robert D, Moyé, Lem, Cogle, Christopher R, Taylor, Doris A

“…RATIONALE:Despite significant interest in bone marrow mononuclear cell (BMC) therapy for ischemic heart disease, current techniques have resulted in only…”
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LateTIME: a phase-II, randomized, double-blinded, placebo-controlled, pilot trial evaluating the safety and effect of administration of bone marrow mononuclear cells 2 to 3 weeks after acute myocardial infarction by Traverse, Jay H, Henry, Timothy D, Vaughan, Douglas E, Ellis, Stephen G, Pepine, Carl J, Willerson, James T, Zhao, David X M, Simpson, Lara M, Penn, Marc S, Byrne, Barry J, Perin, Emerson C, Gee, Adrian P, Hatzopoulos, Antonis K, McKenna, David H, Forder, John R, Taylor, Doris A, Cogle, Christopher R, Baraniuk, Sarah, Olson, Rachel E, Jorgenson, Beth C, Sayre, Shelly L, Vojvodic, Rachel W, Gordon, David J, Skarlatos, Sonia I, Moyè, Lemuel A, Simari, Robert D

“…A realistic goal for cardiac cell therapy may be to attenuate left ventricular remodeling following acute myocardial infarction to prevent the development of…”
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Development of a Network to Test Strategies in Cardiovascular Cell Delivery: The NHLBI-sponsored Cardiovascular Cell Therapy Research Network (CCTRN) by Simari, Robert D., Moyé, Lemuel A., Skarlatos, Sonia I., Ellis, Stephen G., Zhao, David X. M., Willerson, James T., Henry, Timothy D., Pepine, Carl J.

“…The emerging sciences of stem cell biology and cellular plasticity have led to the development of cell-based therapies for advanced human disease. Pre-clinical…”
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Percutaneous Post-Myocardial Infarction Ventricular Septal Rupture Closure: A Review by Andersen, Mousumi M., Zhao, David X. M.

“…Ventricular septal rupture remains a rare, but most often lethal, complication of acute myocardial infarction. Current guidelines recommend emergent surgical…”
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Bone Marrow Cell Characteristics Associated with Patient Profile and Cardiac Performance Outcomes in the LateTIME-CCTRN Trial by Bhatnagar, Aruni, PhD, Bolli, Roberto, MD, Johnstone, Brian H., PhD, Traverse, Jay H., MD, Henry, Timothy D., MD, Pepine, Carl J., MD, Willerson, James T., MD, Perin, Emerson C., MD, PhD, Ellis, Stephen G., MD, Zhao, David X.M., MD, Yang, Phillip C., MD, Cooke, John P., MD, PhD, Schutt, Robert C., MD, MS, Trachtenberg, Barry H., MD, Orozco, Aaron, PhD, Resende, Micheline, PhD, Ebert, Ray F., PhD, Sayre, Shelly L., MPH, Simari, Robert D., MD, Moyé, Lem, MD, PhD, Cogle, Christopher R., MD, Taylor, Doris A., PhD

“…Abstract Background Although several preclinical studies have shown that bone marrow cell (BMC) transplantation promotes cardiac recovery after myocardial…”
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Routine Intraoperative Completion Angiography After Coronary Artery Bypass Grafting and 1-Stop Hybrid Revascularization by Zhao, David X., MD, FACC, Leacche, Marzia, MD, Balaguer, Jorge M., MD, Boudoulas, Konstantinos D., MD, Damp, Julie A., MD, Greelish, James P., MD, Byrne, John G., MD, FACC

“…Objectives This study sought to report our experience with a routine completion angiogram after coronary artery bypass surgery (CABG) and simultaneous (1-stop)…”
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