Search Results - "Zhang, Zhuangli"
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Multifunctional nanoplatform with near-infrared triggered nitric-oxide release for enhanced tumor ferroptosis
Published in Journal of nanobiotechnology (26-10-2024)“…Ferroptosis has emerged as a promising strategy for cancer treatment. Nevertheless, the efficiency of ferroptosis-mediated therapy remains a challenge due to…”
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Oridonin Induces Apoptosis in Esophageal Squamous Cell Carcinoma by Inhibiting Cytoskeletal Protein LASP1 and PDLIM1
Published in Molecules (Basel, Switzerland) (13-01-2023)“…Esophageal squamous cell carcinoma is a severe malignancy for its high mortality and poor prognosis. Mainstay chemotherapies cause serious side effects for…”
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A graph self-supervised residual learning framework for domain identification and data integration of spatial transcriptomics
Published in Communications biology (12-09-2024)“…Spatial transcriptomics (ST) technologies allow for comprehensive characterization of gene expression patterns in the context of tissue microenvironment…”
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Artemisia argyi Essential Oil Inhibits Hepatocellular Carcinoma Metastasis via Suppression of DEPDC1 Dependent Wnt/β-Catenin Signaling Pathway
Published in Frontiers in cell and developmental biology (29-06-2021)“…The tumor metastasis is the major hurdle for the treatment of advanced hepatocellular carcinoma (HCC), due in part to the lack of effective systemic…”
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Surface modified cellulose nanocrystalline hybrids actualizing efficient and precise delivery of doxorubicin into nucleus with: In vitro and in vivo evaluation
Published in Journal of applied polymer science (20-12-2021)“…Rod‐like‐shape nanomedicines with the ability of lysosomal pH‐controlled drug release can precisely deliver doxorubicin (DOX) into its target, nucleus, and can…”
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In vivo anti-hepatitis B activity of Artemisia argyi essential oil-loaded nanostructured lipid carriers. Study of its mechanism of action by network pharmacology and molecular docking
Published in Phytomedicine (Stuttgart) (25-07-2023)“…•Artemisia argyi essential oil displayed potent anti-HBV activity in vitro and in vivo with no significant toxicity.•AAEO loaded nanostructured lipid carriers…”
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Design, synthesis and anticancer evaluation of new 4-anilinoquinoline-3-carbonitrile derivatives as dual EGFR/HER2 inhibitors and apoptosis inducers
Published in Bioorganic chemistry (01-09-2021)“…[Display omitted] •Twelve compounds of 4-anilinoquinoline-3-carbonitrile derivatives were designed and synthesized.•Both 6a and 6dshowed potent EGFR and HER2…”
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Self-Illuminating Near-Infrared Chemiluminescence Nanosensors for Tumor Imaging
Published in ACS applied nano materials (29-05-2024)“…Chemiluminescence (CL) imaging, characterized by its high signal-to-noise ratio, has emerged as a highly promising approach for noninvasive and efficient tumor…”
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