Search Results - "Zhang, Zheng Wei"
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Why Does Hyperuricemia Not Necessarily Induce Gout?
Published in Biomolecules (Basel, Switzerland) (14-02-2021)“…Hyperuricemia is a risk factor for gout. It has been well observed that a large proportion of individuals with hyperuricemia have never had a gout flare(s),…”
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Oral berberine improves brain dopa/dopamine levels to ameliorate Parkinson’s disease by regulating gut microbiota
Published in Signal transduction and targeted therapy (24-02-2021)“…The phenylalanine–tyrosine–dopa–dopamine pathway provides dopamine to the brain. In this process, tyrosine hydroxylase (TH) is the rate-limiting enzyme that…”
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3
Synergistic effects of conductive carbon nanofillers based on the ultrahigh‐molecular‐weight polyethylene with uniform and segregated structures
Published in Journal of applied polymer science (10-04-2019)“…ABSTRACT To discuss the synergistic effects of mixed conductive filler on nanocomposites, different structural carbon nanofiller/ultrahigh‐molecular‐weight…”
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4
STING‐mediated inflammation contributes to Gao binge ethanol feeding model
Published in Journal of cellular physiology (01-02-2022)“…Alcohol metabolism causes hepatocytes to release damage‐associated molecular patterns (DAMPs). This includes mitochondrial DNA (mtDNA), which is generated and…”
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5
A statistical model for restoration of serum potassium level disturbed by hemolysis
Published in Clinica chimica acta (01-10-2019)“…Blood sample hemolysis affects pre-analytical quality and may cause pseudohyperkalemia. We established a statistical model to estimate the corrected potassium…”
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Morinda officinalis oligosaccharides increase serotonin in the brain and ameliorate depression via promoting 5-hydroxytryptophan production in the gut microbiota
Published in Acta pharmaceutica Sinica. B (01-08-2022)“…Morinda officinalis oligosaccharides (MOO) are an oral drug approved in China for the treatment of depression in China. However, MOO is hardly absorbed so that…”
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Biotransformation of Timosaponin BII into Seven Characteristic Metabolites by the Gut Microbiota
Published in Molecules (Basel, Switzerland) (24-06-2021)“…Timosaponin BII is one of the most abundant Anemarrhena saponins and is in a phase II clinical trial for the treatment of dementia. However, the…”
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Berberine treats atherosclerosis via a vitamine-like effect down-regulating Choline-TMA-TMAO production pathway in gut microbiota
Published in Signal transduction and targeted therapy (07-07-2022)“…Trimethylamine- N -oxide (TMAO) derived from the gut microbiota is an atherogenic metabolite. This study investigates whether or not berberine (BBR) could…”
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Transforming of Triptolide into Characteristic Metabolites by the Gut Microbiota
Published in Molecules (Basel, Switzerland) (30-01-2020)“…The importance of the gut microbiota in drug metabolism, especially in that of nonabsorbable drugs, has become known. The aim of this study was to explore the…”
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Accretionary orogenesis triggered by collision across continent distance: Evidence from the Proto‐Tethyan West Kunlun, China
Published in Terra nova (Oxford, England) (01-06-2023)“…Proto‐Tethyan orogenic processes prior to the late Ordovician collision remain unclear. Both whole‐rock La/Yb‐ and zircon Eu/Eu*‐based crustal thickness…”
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11
miR-20a Promotes Prostate Cancer Invasion and Migration Through Targeting ABL2
Published in Journal of cellular biochemistry (01-07-2014)“…ABSTRACT The aberrant expression of microRNAs (miRNAs) has been found in various types of cancer. The present study found miR‐20a was significantly…”
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Determination of berberine-upregulated endogenous short-chain fatty acids through derivatization by 2-bromoacetophenone
Published in Analytical and bioanalytical chemistry (01-05-2019)“…Short-chain fatty acids (SCFAs) are a major group of endogenous metabolites generated by the gut microbiota and have been reported to play an important role in…”
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Gut Microbiota-Based Pharmacokinetics and the Antidepressant Mechanism of Paeoniflorin
Published in Frontiers in pharmacology (20-03-2019)“…Paeoniflorin, the main component of Xiaoyao Wan, presents low oral bioavailability and unclear antidepressant mechanism. To elucidate the potential reasons for…”
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Determination and Application of Nineteen Monoamines in the Gut Microbiota Targeting Phenylalanine, Tryptophan, and Glutamic Acid Metabolic Pathways
Published in Molecules (Basel, Switzerland) (04-03-2021)“…It has been reported that monoamine neurotransmitters can be produced by gut microbiota, and that several related metabolites of amino acids in these pathways…”
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Transformation of berberine to its demethylated metabolites by the CYP51 enzyme in the gut microbiota
Published in Journal of pharmaceutical analysis (01-10-2021)“…Berberine (BBR) is an isoquinoline alkaloid extracted from Coptis chinensis that improves diabetes, hyperlipidemia and inflammation. Due to the low oral…”
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Advances in the two-dimensional layer materials for cancer diagnosis and treatment: unique advantages beyond the microsphere
Published in Frontiers in bioengineering and biotechnology (29-09-2023)“…In recent years, two-dimensional (2D) layer materials have shown great potential in the field of cancer diagnosis and treatment due to their unique structural,…”
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Calcifying pseudoneoplasms of the neuraxis (CAPNON). A case report
Published in Neuropathology (01-10-2021)“…Calcifying pseudoneoplasms of the neuraxis (CAPNON) are rare, slow‐growing, benign lesions occurring throughout the neuroaxis that are frequently misdiagnosed…”
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18
Influence of overflow port selection on the gas desulfurization of gas cyclone–liquid jet absorption separator
Published in Asia-Pacific journal of chemical engineering (01-07-2020)“…The purification of industrial sulfur‐containing tail gas mainly adopts the wet flue gas desulfurization of gas–liquid mass transfer, and a new separator…”
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Esterases From Bifidobacteria Exhibit the Conversion of Albiflorin in Gut Microbiota
Published in Frontiers in microbiology (06-04-2022)“…is an important microbe that inhabits the human gut. It is capable of metabolizing complex compounds in the human diet. Albiflorin, an antidepressant natural…”
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Metabolites Analysis of Anti-Myocardial Ischemia Active Components of Saussurea involucrata Based on Gut Microbiota-Drug Interaction
Published in International journal of molecular sciences (05-07-2022)“…has been reported to have potential therapeutic effects against myocardial ischemia. The pharmacological effects of oral natural medicines may be influenced by…”
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