Search Results - "Zhang, Zengdi"

Bone marrow adipose tissue-derived stem cell factor mediates metabolic regulation of hematopoiesis by Zhang, Zengdi, Huang, Zan, Ong, Brianna, Sahu, Chinmayi, Zeng, Hu, Ruan, Hai-Bin

“…Hematopoiesis is dynamically regulated by metabolic cues in homeostatic and stressed conditions; however, the cellular and molecular mechanisms mediating the…”
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Supraclavicular brown adipocytes originate from Tbx1+ myoprogenitors by Huang, Zan, Gu, Chenxin, Zhang, Zengdi, Arianti, Rini, Swaminathan, Aneesh, Tran, Kevin, Battist, Alex, Kristóf, Endre, Ruan, Hai-Bin

“…Brown adipose tissue (BAT) dissipates energy as heat, contributing to temperature control, energy expenditure, and systemic homeostasis. In adult humans, BAT…”
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Requirement of Smurf-mediated endocytosis of Patched1 in sonic hedgehog signal reception by Yue, Shen, Tang, Liu-Ya, Tang, Ying, Tang, Yi, Shen, Qiu-Hong, Ding, Jie, Chen, Yan, Zhang, Zengdi, Yu, Ting-Ting, Zhang, Ying E, Cheng, Steven Y

“…Cell surface reception of Sonic hedgehog (Shh) must ensure that the graded morphogenic signal is interpreted accordingly in neighboring cells to specify tissue…”
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Protein O-GlcNAc Modification Links Dietary and Gut Microbial Cues to the Differentiation of Enteroendocrine L Cells by Zhao, Ming, Ren, Kaiqun, Xiong, Xiwen, Cheng, Meng, Zhang, Zengdi, Huang, Zan, Han, Xiaonan, Yang, Xiaoyong, Alejandro, Emilyn U., Ruan, Hai-Bin

“…Intestinal L cells regulate a wide range of metabolic processes, and L-cell dysfunction has been implicated in the pathogenesis of obesity and diabetes…”
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O-GlcNAc glycosylation orchestrates fate decision and niche function of bone marrow stromal progenitors by Zhang, Zengdi, Huang, Zan, Awad, Mohamed, Elsalanty, Mohammed, Cray, James, Ball, Lauren E, Maynard, Jason C, Burlingame, Alma L, Zeng, Hu, Mansky, Kim C, Ruan, Hai-Bin

“…In mammals, interactions between the bone marrow (BM) stroma and hematopoietic progenitors contribute to bone-BM homeostasis. Perinatal bone growth and…”
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An OGT-STAT5 Axis in Regulatory T Cells Controls Energy and Iron Metabolism by Zhang, Zengdi, Salgado, Oscar C, Liu, Bing, Moazzami, Zahra, Hogquist, Kristin A, Farrar, Michael A, Ruan, Hai-Bin

“…The immunosuppressive regulatory T (Treg) cells exert emerging effects on adipose tissue homeostasis and systemic metabolism. However, the metabolic regulation…”
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The miR-183--96-182 cluster promotes tumorigenesis in a mouse model of medulloblastoma by Zhang, Zengdi, Li, Sanen, Cheng, Steven Y

“…Medulloblastoma is the most common malignant pediatric brain tumor. Some are thought to originate from cerebellar granule neuron progenitors （CGNPs） that fail…”
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Abstract 1540: O-GlcNAc glycosylation orchestrates fate decision and niche function of bone marrow stromal progenitors by Ruan, Hai-Bin, Zhang, Zengdi, Huang, Zan

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7-OR: Distinct Developmental Origins of Brown Adipose Tissue at Different Anatomical Locations by RUAN, HAI-BIN, ZHANG, ZENGDI, HUANG, ZAN

“…Brown adipose tissue (BAT) is a thermogenic organ that promotes metabolic fitness. In humans, there are two spatiotemporally distinct phases of BAT ontogeny:…”
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Supraclavicular brown adipocytes arise from myogenic Tbx1-lineage progenitors by Ruan, Hai-Bin, Huang, Zan, Zhang, Zengdi

“…Abstract only Brown adipose tissue (BAT) is a thermogenic organ that promotes metabolic fitness. In humans, there are two spatiotemporally distinct phases of…”
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MiR-107 induces TNF-α secretion in endothelial cells causing tubular cell injury in patients with septic acute kidney injury by Wang, Shanshan, Zhang, Zengdi, Wang, Jun, Miao, Hongjun

“…Activation of endothelial cells plays a key role in septic acute kidney injury (AKI). This study investigated the role of miRNA in endothelial-induced tubular…”
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312-OR: Functional Decline in Brown Adipose Progenitors during BAT Remodeling by HUANG, ZAN, ZHANG, ZENGDI, RUAN, HAI-BIN

“…In humans, there is a striking decrease in the prevalence and activity of brown adipose tissue (BAT) with age and obesity; however, the cellular and molecular…”
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1919-P: Regulation and Function of Bone Marrow Adipocytes in Osteogenesis and Hematopoiesis by ZHANG, ZENGDI, HUANG, ZAN, RUAN, HAI-BIN

“…In the bone marrow stroma, skeletal stem cells (SSCs) and their derived stromal cells, osteoblasts and bone marrow adipocytes (BMAs) provide the niche…”
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Functional decline in brown adipose progenitors during BAT remodeling by Ruan, Hai‐Bin, Huang, Zan, Zhang, Zengdi

“…In humans, there is a striking decrease in the prevalence and activity of brown adipose tissue (BAT) with age and obesity; however, the cellular and molecular…”
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Supraclavicular brown adipocytes originate from Tbx1.sup.+ myoprogenitors by Huang, Zan, Gu, Chenxin, Zhang, Zengdi, Arianti, Rini, Swaminathan, Aneesh, Tran, Kevin, Battist, Alex, Kristóf, Endre, Ruan, Hai-Bin

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Epithelial STAT6 O-GlcNAcylation drives a concerted anti-helminth alarmin response dependent on tuft cell hyperplasia and Gasdermin C by Zhao, Ming, Ren, Kaiqun, Xiong, Xiwen, Xin, Yue, Zou, Yujie, Maynard, Jason C., Kim, Angela, Battist, Alexander P., Koneripalli, Navya, Wang, Yusu, Chen, Qianyue, Xin, Ruyue, Yang, Chenyan, Huang, Rong, Yu, Jiahui, Huang, Zan, Zhang, Zengdi, Wang, Haiguang, Wang, Daoyuan, Xiao, Yihui, Salgado, Oscar C., Jarjour, Nicholas N., Hogquist, Kristin A., Revelo, Xavier S., Burlingame, Alma L., Gao, Xiang, von Moltke, Jakob, Lin, Zhaoyu, Ruan, Hai-Bin

“…The epithelium is an integral component of mucosal barrier and host immunity. Following helminth infection, the intestinal epithelial cells secrete “alarmin”…”
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Decreased miR-128 and increased miR-21 synergistically cause podocyte injury in sepsis by Wang, Shanshan, Wang, Jun, Zhang, Zengdi, Miao, Hongjun

“…Objective Glomerular podocytes are injured in sepsis. We studied, in a sepsis patient, whether microRNAs (miRNAs) play a role in the podocyte injury. Methods…”
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Brown adipose tissue involution associated with progressive restriction in progenitor competence by Huang, Zan, Zhang, Zengdi, Moazzami, Zahra, Heck, Ryan, Hu, Ping, Nanda, Hezkiel, Ren, Kaiqun, Sun, Zequn, Bartolomucci, Alessandro, Gao, Yan, Chung, Dongjun, Zhu, Weiyun, Shen, Steven, Ruan, Hai-Bin

“…Human brown adipose tissue (BAT) undergoes progressive involution. This involution process is not recapitulated in rodents, and the underlying mechanisms are…”
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Epithelial STAT6 O-GlcNAcylation drives a concerted anti-helminth alarmin response dependent on tuft cell hyperplasia and Gasdermin C by Zhao, Ming, Ren, Kaiqun, Xiong, Xiwen, Xin, Yue, Zou, Yujie, Maynard, Jason C., Kim, Angela, Battist, Alexander P., Koneripalli, Navya, Wang, Yusu, Chen, Qianyue, Xin, Ruyue, Yang, Chenyan, Huang, Rong, Yu, Jiahui, Huang, Zan, Zhang, Zengdi, Wang, Haiguang, Wang, Daoyuan, Xiao, Yihui, Salgado, Oscar C., Jarjour, Nicholas N., Hogquist, Kristin A., Revelo, Xavier S., Burlingame, Alma L., Gao, Xiang, von Moltke, Jakob, Lin, Zhaoyu, Ruan, Hai-Bin

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Suppressor of Fused Chaperones Gli Proteins To Generate Transcriptional Responses to Sonic Hedgehog Signaling by Zhang, Ziyu, Shen, Longyan, Law, Kelvin, Zhang, Zengdi, Liu, Xiaotong, Hua, Hu, Li, Sanen, Huang, Huijie, Yue, Shen, Hui, Chi-chung, Cheng, Steven Y.

“…Cellular responses to the graded Sonic Hedgehog (Shh) morphogenic signal are orchestrated by three Gli genes that give rise to both transcription activators…”
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