Search Results - "Zhang, Yuan‐Liang"
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1
Threonine dehydrogenase regulates neutrophil homeostasis but not H3K4me3 levels in zebrafish
Published in The FEBS journal (01-08-2024)“…l‐threonine dehydrogenase (Tdh) is an enzyme that links threonine metabolism to epigenetic modifications and mitochondria biogenesis. In vitro studies show…”
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Journal Article -
2
Setd2 deficiency impairs hematopoietic stem cell self-renewal and causes malignant transformation
Published in Cell research (01-04-2018)“…The histone H3 lysine 36 methyltransferase SETD2 is frequently mutated in various cancers, including leukemia. However, there has not been any functional model…”
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3
Histone H3 lysine 36 methyltransferase Hypb/Setd2 is required for embryonic vascular remodeling
Published in Proceedings of the National Academy of Sciences - PNAS (16-02-2010)“…HYPB is a human histone H3 lysine 36 (H3K36)-specific methyltransferase and acts as the ortholog of yeast Set2. This study explored the physiological function…”
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4
Destabilization of AETFC through C/EBPα-mediated repression of LYL1 contributes to t(8;21) leukemic cell differentiation
Published in Leukemia (01-07-2019)Get full text
Journal Article -
5
Selective and competitive functions of the AAR and UPR pathways in stress-induced angiogenesis
Published in Cell discovery (26-10-2021)“…The amino acid response (AAR) and unfolded protein response (UPR) pathways converge on eIF2α phosphorylation, which is catalyzed by Gcn2 and Perk,…”
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Discretization of Nonlinear Non-affine Time Delay Systems Based on Second-order Hold
Published in International journal of automation and computing (01-06-2014)“…When calculating the sampled-date representation of nonlinear systems second-order hold(SOH) assumption can be applied to improving the precision of the…”
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7
A direct comparison between AML1-ETO and ETO2-GLIS2 leukemia fusion proteins reveals context-dependent binding and regulation of target genes and opposite functions in cell differentiation
Published in Frontiers in cell and developmental biology (07-09-2022)“…The ETO-family transcriptional corepressors, including ETO, ETO2, and MTGR1, are all involved in leukemia-causing chromosomal translocations. In every case, an…”
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8
A discretization method for nonlinear delayed non-affine systems
Published in International journal of automation and computing (01-04-2012)“…The input time delay is always existent in the practical systems. Analysis of the delay phenomenon in a continuous-time domain is sophisticated. It is…”
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9
SETD2 deficiency accelerates MDS-associated leukemogenesis via S100a9 in NHD13 mice and predicts poor prognosis in MDS
Published in Blood (18-06-2020)“…SETD2, the histone H3 lysine 36 methyltransferase, previously identified by us, plays an important role in the pathogenesis of hematologic malignancies, but…”
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10
The fatigue failure analysis and fatigue life prediction model of FV520B-I as a function of surface roughness in HCF regime
Published in Journal of materials research (14-02-2017)“…The high-cycle fatigue (HCF) behavior is significantly affected by surface roughness, especially for high strength metal FV520B-I. However, with surface…”
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Journal Article -
11
Different roles of E proteins in t(8;21) leukemia: E2-2 compromises the function of AETFC and negatively regulates leukemogenesis
Published in Proceedings of the National Academy of Sciences - PNAS (15-01-2019)“…The AML1-ETO fusion protein, generated by the t(8;21) chromosomal translocation, is causally involved in nearly 20% of acute myeloid leukemia (AML) cases. In…”
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12
setd2 knockout zebrafish is viable and fertile: differential and developmental stress-related requirements for Setd2 and histone H3K36 trimethylation in different vertebrate animals
Published in Cell discovery (20-10-2020)“…Setd2 is the only enzyme that catalyzes histone H3 lysine 36 trimethylation (H3K36me3) on virtually all actively transcribed protein-coding genes, and this…”
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13
Construction of multiple shRNAs expression vector that inhibits FUT1 gene expression and production of the transgenic SCNT embryos in vitro
Published in Molecular biology reports (01-03-2013)“…Enterotoxigenic Escherichia coli F18 is a major pathogen that causes postweaning diarrhoea and edema disease in piglets. The alpha(1,2)-fucosyltransferase (…”
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Effect of GATA-2 overexpression on function of mouse fetal liver hematopoietic stem cells
Published in Zhongguo shi yan xue ye xue za zhi (01-08-2013)“…This study was aimed to investigate the effect of GATA-2 over-expression on function of mouse fetal liver hematopoietic stem cells. GATA-2 was introduced into…”
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Journal Article -
15
Incipient Fault Feature Extraction of Rolling Bearing Based on Full Vector Complete Ensemble Empirical Mode Decomposition
Published in 2019 International Conference on Quality, Reliability, Risk, Maintenance, and Safety Engineering (QR2MSE) (01-08-2019)“…Feature extraction plays a crucial role in the rolling bearing fault diagnosis, which determines the results of the fault diagnosis largely. However,…”
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Conference Proceeding -
16
Destabilization of AETFC through C/EBP[alpha]-mediated repression of LYL1 contributes to t(8;21) leukemic cell differentiation
Published in Leukemia (01-07-2019)Get full text
Journal Article -
17
Dermoscopic image segmentation based on Pyramid Residual Attention Module
Published in PloS one (16-09-2022)“…We propose a stacked convolutional neural network incorporating a novel and efficient pyramid residual attention (PRA) module for the task of automatic…”
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Journal Article -
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Angiogenesis Induced By Aminoacyl-tRNA Synthetase Deficiency Is Dependent on Amino Acid Response (AAR) but Not Unfolded Protein Response (UPR) Pathways
Published in Blood (29-11-2018)“…Stress-induced angiogenesis enormously contributes to both normal development and pathogenesis of various diseases including cancer. Among many stress response…”
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Journal Article -
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The fatigue failure analysis and fatigue life prediction model of F[ARMENIAN SMALL LETTER ECH]20B-I as a function of surface roughness in HCF regime
Published in Journal of materials research (14-02-2017)“…The high-cycle fatigue (HCF) behavior is significantly affected by surface roughness, especially for high strength metal F[ARMENIAN SMALL LETTER ECH]20B-I…”
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Journal Article -
20
Differential Expression of CD49f Discriminates the Independently Emerged Hematopoietic Stem Cells and Erythroid-Biased Progenitors
Published in Blood (13-11-2019)“…While hematopoietic stem cells (HSCs) can sustain the production of all types of mature blood cells throughout the life, there also exists HSC-independent…”
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Journal Article