Search Results - "Zhang, Xuxia"
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1
Induction of lysosomal exocytosis and biogenesis via TRPML1 activation for the treatment of uranium-induced nephrotoxicity
Published in Nature communications (06-07-2023)“…Uranium (U) is a well-known nephrotoxicant which forms precipitates in the lysosomes of renal proximal tubular epithelial cells (PTECs) after U-exposure at a…”
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2
Effect of Composition of PDMAEMA‑b‑PAA Block Copolymers on Their pH- and Temperature-Responsive Behaviors
Published in Langmuir (29-01-2013)“…A series of poly(2-(dimethylamino) ethyl methacrylate) (PDMAEMA) homopolymers and poly(2-(dimethylamino)ethyl methacrylate)-b-poly(acrylic acid)…”
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3
Development and clinical evaluation of a CRISPR/Cas13a-based diagnostic test to detect Mycobacterium tuberculosis in clinical specimens
Published in Frontiers in microbiology (03-02-2023)“…Tuberculosis diagnosis requires rapid, simple and highly sensitive methods. Clustered regularly interspaced short palindromic repeats (CRISPRs) and associated…”
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Characterization of Mycobacterium tuberculosis strains in Beijing, China: drug susceptibility phenotypes and Beijing genotype family transmission
Published in BMC infectious diseases (14-12-2018)“…The most prevalent strains of Mycobacterium tuberculosis (M.tb) in Beijing belong to the Beijing genotype family. The influence of Beijing genotype prevalence…”
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Prevalence and Risk Factors of Subclinical Tuberculosis in a Low-Incidence Setting in China
Published in Frontiers in microbiology (11-01-2022)“…Subclinical tuberculosis (TB) represents a substantial proportion of individuals with TB disease, although limited evidence is available to understand the…”
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Deciphering the possible role of MmpL7 efflux pump in SQ109 resistance in Mycobacterium tuberculosis
Published in Annals of clinical microbiology and antimicrobials (28-09-2024)“…SQ109 is a promising candidate drug for the treatment of patients with drug-resistant tuberculosis (DR-TB). The purpose of this study was to investigate the…”
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The study on the association between Beijing genotype family and drug susceptibility phenotypes of Mycobacterium tuberculosis in Beijing
Published in Scientific reports (08-11-2017)“…The predominant prevalent Mycobacterium tuberculosis ( M . tb ) lineage was the Beijing genotype family in Beijing. There has been no systematic study on the…”
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In vitro susceptibility of nontuberculous mycobacteria in China
Published in BMC infectious diseases (23-01-2024)“…This study aimed to measure the prevalence of resistance to antimicrobial agents, and explore the risk factors associated with drug resistance by using…”
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9
Antigen-specific chemokine profiles as biomarkers for detecting Mycobacterium tuberculosis infection
Published in Frontiers in immunology (06-03-2024)“…Latent tuberculosis (TB) infection can progress to active TB, which perpetuates community transmission that undermines global TB control efforts. Clinically,…”
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10
Predominance of Escherichia-Shigella in Gut Microbiome and Its Potential Correlation with Elevated Level of Plasma Tumor Necrosis Factor Alpha in Patients with Tuberculous Meningitis
Published in Microbiology spectrum (21-12-2022)“…Tuberculous meningitis (TBM), the most lethal and disabling form of tuberculosis (TB), may be related to gut microbiota composition, warranting further study…”
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11
Highly Discriminative Genotyping of Mycobacterium abscessus Complex Using a Set of Variable Number Tandem Repeats in China
Published in Frontiers in microbiology (31-01-2022)“…In this study, our aims were to comparatively analyze the power of variable number tandem repeat (VNTR) typing to discriminate isolates within subspecies and…”
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12
Distinguishing Relapse From Reinfection With Whole-Genome Sequencing in Recurrent Pulmonary Tuberculosis: A Retrospective Cohort Study in Beijing, China
Published in Frontiers in microbiology (08-12-2021)“…Tuberculosis recurrence is still a major problem for the control of tuberculosis, and the cause of the recurrence is still unclear. We retrospectively…”
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13
Surveillance of close contacts of patients with infectious tuberculosis: a prospective cohort study
Published in Antimicrobial resistance & infection control (09-06-2024)“…A long-term follow-up of close contacts to monitor their infection status is essential to formulate a promising screening strategy. The study aimed to assess…”
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14
Analysis of Xpert MTB/RIF results in retested patients with very low initial bacterial loads: A retrospective study in China
Published in Journal of infection and public health (01-06-2023)“…The Xpert MTB/RIF (Xpert) assay has been widely used to diagnose suspected active tuberculosis (TB) and rifampicin-resistant TB cases. Despite its excellent…”
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15
The emerging threat of fluroquinolone-, bedaquiline-, and linezolid-resistant Mycobacterium tuberculosis in China: Observations on surveillance data
Published in Journal of infection and public health (01-01-2024)“…Drug-resistant tuberculosis (TB), especially multidrug-resistant tuberculosis (MDR-TB), constitutes a major obstacle to fulfill end TB strategy globally…”
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16
Diagnostic accuracy of oral swab for detection of pulmonary tuberculosis: a systematic review and meta-analysis
Published in Frontiers in medicine (11-03-2024)“…Tuberculosis (TB) remains a significant concern in terms of public health, necessitating the timely and accurate diagnosis to impede its advancement. The…”
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17
Aluminum Removal from Rare Earth Chloride Solution through Regulated Hydrolysis via Electrochemical Method
Published in Separations (01-05-2024)“…Due to the coexistence of Al3+ and RE3+ and their similar properties, the separation of aluminum from rare earths is difficult. In this study, selective…”
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Prevalence of extensively drug-resistant tuberculosis in a Chinese multidrug-resistant TB cohort after redefinition
Published in Antimicrobial resistance & infection control (26-08-2021)“…Recently, the definition of extensively drug-resistant TB (XDR-TB) has been revised. In this study, we conducted a descriptive and retrospective study to…”
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Reevaluating Rifampicin Breakpoint Concentrations for Mycobacterium tuberculosis Isolates with Disputed rpoB Mutations and Discordant Susceptibility Phenotypes
Published in Microbiology spectrum (23-02-2022)“…In this study, rifampicin resistance breakpoints based on MICs of disrupted mutants of Mycobacterium tuberculosis (MTB) were explored using the Mycobacteria…”
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20
Thermoresponsive Diblock Copolymer with Tunable Soluble-Insoluble and Soluble-Insoluble-Soluble Transitions
Published in Macromolecular rapid communications. (12-04-2013)“…The thermoresponsive transition behavior of a diblock copolymer consisting of poly(ethylene glycol) methyl ether (mPEG) and poly(N,N‐dimethylaminoethyl…”
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