Search Results - "Zhang, Xuanping"
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Health improvements of type 2 diabetic patients through diet and diet plus fecal microbiota transplantation
Published in Scientific reports (21-01-2022)“…Type 2 diabetes (T2D) is a major public health problem, and gut microbiota dysbiosis has been implicated in the emergence of T2D in humans. Dietary…”
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Deep sequencing of circulating tumor DNA detects molecular residual disease and predicts recurrence in gastric cancer
Published in Cell death & disease (11-05-2020)“…Identifying locoregional gastric cancer patients who are at high risk for relapse after resection could facilitate early intervention. By detecting molecular…”
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Cost-Effectiveness of Interventions to Prevent and Control Diabetes Mellitus: A Systematic Review
Published in Diabetes care (01-08-2010)“…To synthesize the cost-effectiveness (CE) of interventions to prevent and control diabetes, its complications, and comorbidities. We conducted a systematic…”
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An independent evaluation in a CRC patient cohort of microbiome 16S rRNA sequence analysis methods: OTU clustering, DADA2, and Deblur
Published in Frontiers in microbiology (25-07-2023)“…16S rRNA is the universal gene of microbes, and it is often used as a target gene to obtain profiles of microbial communities via next-generation sequencing…”
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A Chinese multicenter retrospective study of isolated increased nuchal translucency associated chromosome anomaly and prenatal diagnostic suggestions
Published in Scientific reports (10-03-2021)“…Extensive researches involving fetuses with multiple ultrasound anomalies have been conducted over the years, but only few were focused on the isolated…”
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OCRDetector: Accurately Detecting Open Chromatin Regions via Plasma Cell-Free DNA Sequencing Data
Published in International journal of molecular sciences (28-05-2021)“…Open chromatin regions (OCRs) are special regions of the human genome that can be accessed by DNA regulatory elements. Several studies have reported that a…”
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A1C Level and Future Risk of Diabetes: A Systematic Review
Published in Diabetes care (01-07-2010)“…We examined ranges of A1C useful for identifying persons at high risk for diabetes prior to preventive intervention by conducting a systematic review. From 16…”
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An Efficient Algorithm for Sensitively Detecting Circular RNA from RNA-seq Data
Published in International journal of molecular sciences (24-09-2018)“…Circular RNA (circRNA) is an important member of non-coding RNA family. Numerous computational methods for detecting circRNAs from RNA-seq data have been…”
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TCRcost: a deep learning model utilizing TCR 3D structure for enhanced of TCR-peptide binding
Published in Frontiers in genetics (02-10-2024)“…Predicting TCR-peptide binding is a complex and significant computational problem in systems immunology. During the past decade, a series of computational…”
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Downregulation of cytokeratin 18 induces cellular partial EMT and stemness through increasing EpCAM expression in breast cancer
Published in Cellular signalling (01-12-2020)“…Induction of epithelial-mesenchymal transition (EMT) and cancer stem cell (CSC) characteristics underlie the development of metastasis, chemoresistance, and…”
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Hesperetin inhibits rat coronary constriction by inhibiting Ca2+ influx and enhancing voltage-gated K+ channel currents of the myocytes
Published in European journal of pharmacology (15-07-2014)“…Hesperetin (HSP, one of the most common flavonoids in Citrus) has been reported to possess many benificial effects and is indicated for many diseases both as a…”
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Improved diagnostic efficiency of CRC subgroups revealed using machine learning based on intestinal microbes
Published in BMC gastroenterology (17-09-2024)“…Colorectal cancer (CRC) is a common cancer that causes millions of deaths worldwide each year. At present, numerous studies have confirmed that intestinal…”
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Effect of lifestyle interventions on cardiovascular risk factors among adults without impaired glucose tolerance or diabetes: A systematic review and meta-analysis
Published in PloS one (11-05-2017)“…Structured lifestyle interventions can reduce diabetes incidence and cardiovascular disease (CVD) risk among persons with impaired glucose tolerance (IGT), but…”
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DeepLION: Deep Multi-Instance Learning Improves the Prediction of Cancer-Associated T Cell Receptors for Accurate Cancer Detection
Published in Frontiers in genetics (11-04-2022)“…Recent studies highlight the potential of T cell receptor (TCR) repertoires in accurately detecting cancers noninvasive sampling. Unfortunately, due to the…”
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Health Care Providers’ Knowledge, Attitudes, and Practices and the Association With Referrals to the National Diabetes Prevention Program Lifestyle Change Program
Published in American journal of health promotion (01-02-2022)“…Purpose To examine how health care providers’ knowledge, attitudes, and practices affect their referrals to the National Diabetes Prevention Program. Design…”
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TMBcat: A multi-endpoint p-value criterion on different discrepancy metrics for superiorly inferring tumor mutation burden thresholds
Published in Frontiers in immunology (16-09-2022)“…Tumor mutation burden (TMB) is a widely recognized stratification biomarker for predicting the efficacy of immunotherapy; however, the number and universal…”
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DeepLION2: deep multi-instance contrastive learning framework enhancing the prediction of cancer-associated T cell receptors by attention strategy on motifs
Published in Frontiers in immunology (07-03-2024)“…T cell receptor (TCR) repertoires provide valuable insights into complex human diseases, including cancers. Recent advancements in immune sequencing technology…”
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Clinicopathological differences of high Fusobacterium nucleatum levels in colorectal cancer: A review and meta-analysis
Published in Frontiers in microbiology (04-11-2022)“…Objective To systematically evaluate the significance of Fusobacterium nucleatum (Fn) levels the clinicopathological impacts of cancer. Methods Literature from…”
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Integration of Protein-Protein Interaction Networks and Gene Expression Profiles Helps Detect Pancreatic Adenocarcinoma Candidate Genes
Published in Frontiers in genetics (26-05-2022)“…More and more cancer-associated genes (CAGs) are being identified with the development of biological mechanism research. Integrative analysis of…”
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What makes TMB an ambivalent biomarker for immunotherapy? A subtle mismatch between the sample-based design of variant callers and real clinical cohort
Published in Frontiers in immunology (25-05-2023)“…Tumor mutation burden (TMB) is a widely recognized biomarker for predicting the efficacy of immunotherapy. However, its use still remains highly controversial…”
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