Search Results - "Zhang, Tuo"
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Mechanisms of neuronal cell death in ischemic stroke and their therapeutic implications
Published in Medicinal research reviews (01-01-2022)“…Ischemic stroke caused by arterial occlusion is the most common type of stroke, which is among the most frequent causes of disability and death worldwide…”
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Iron, ferroptosis, and ischemic stroke
Published in Journal of neurochemistry (01-05-2023)“…Over 30 million people suffer from the consequences of ischemic stroke. The precise molecular mechanism of neuronal damage during ischemic stroke remains…”
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Ferroptosis: mechanisms and links with diseases
Published in Signal transduction and targeted therapy (03-02-2021)“…Ferroptosis is an iron-dependent cell death, which is different from apoptosis, necrosis, autophagy, and other forms of cell death. The process of ferroptotic…”
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Ferroptosis, a Recent Defined Form of Critical Cell Death in Neurological Disorders
Published in Journal of molecular neuroscience (01-10-2018)“…Ferroptosis is a recently defined form of cell death with the involvement of iron and reactive oxygen species (ROS), which is distinct from apoptosis,…”
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The protected polluters: Empirical evidence from the national environmental information disclosure program in China
Published in Journal of cleaner production (10-06-2020)“…As a bottom-up approach, the effectiveness of the environmental information transparency policy hinges on a broad societal ecosystem, including elements such…”
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Cell density impacts the susceptibility to ferroptosis by modulating IRP1‐mediated iron homeostasis
Published in Journal of neurochemistry (01-07-2024)“…Ferroptosis has been implicated in several neurological disorders and may be therapeutically targeted. However, the susceptibility to ferroptosis varies in…”
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circRNA-miRNA-mRNA regulatory network in human lung cancer: an update
Published in Cancer cell international (19-05-2020)“…Circular RNAs, as hopeful diagnosis markers and therapeutic molecules, have been studied, probed and applied into several diseases, such as cardiovascular…”
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Iron promotes the clearance of α-synuclein: An Editorial for 'H63D variant of the homeostatic iron regulator (HFE) gene alters α-synuclein expression, aggregation, and toxicity" on page 177
Published in Journal of neurochemistry (01-09-2020)“…Both elevated iron and α-synuclein (α-syn) aggregates are neuropathological hallmarks of Parkinson's disease (PD). It has been previously shown that iron…”
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Mechanisms of Oocyte Maturation and Related Epigenetic Regulation
Published in Frontiers in cell and developmental biology (19-03-2021)“…Meiosis is the basis of sexual reproduction. In female mammals, meiosis of oocytes starts before birth and sustains at the dictyate stage of meiotic prophase I…”
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Gold-Catalyzed Highly Selective Photoredox C(sp2)−H Difluoroalkylation and Perfluoroalkylation of Hydrazones
Published in Angewandte Chemie International Edition (18-02-2016)“…The first gold‐catalyzed photoredox C(sp2)−H difluoroalkylation and perfluoroalkylation of hydrazones with readily available RF−Br reagents is reported. The…”
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The pathological role of ferroptosis in ischemia/reperfusion-related injury
Published in Dōngwùxué yánjiū (18-05-2020)“…Ischemia/reperfusion (I/R) is a pathological process that occurs in numerous organs throughout the human body, and it is frequently associated with severe…”
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Structural insights of ZIP4 extracellular domain critical for optimal zinc transport
Published in Nature communications (20-06-2016)“…The ZIP zinc transporter family is responsible for zinc uptake from the extracellular milieu or intracellular vesicles. The LIV-1 subfamily, containing nine…”
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Discovery of a periosteal stem cell mediating intramembranous bone formation
Published in Nature (London) (01-10-2018)“…Bone consists of separate inner endosteal and outer periosteal compartments, each with distinct contributions to bone physiology and each maintaining separate…”
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His-Mediated Reversible Self-Assembly of Ferritin Nanocages through Two Different Switches for Encapsulation of Cargo Molecules
Published in ACS nano (22-12-2020)“…Protein nanocages represent a class of nanovehicles for a variety of applications. However, precise manipulation of self-assembly behavior of these protein…”
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Spatial distribution, fractions and risk assessment of five heavy metals in the sediments of Jialing River: a tributary of the Yangtze
Published in Environmental earth sciences (01-10-2020)“…Jialing River is one of the largest tributaries of the Yangtze River and the tributary with the most extensive drainage area among all the tributaries. In…”
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Zinc homeostasis and regulation: Zinc transmembrane transport through transporters
Published in Critical reviews in food science and nutrition (03-10-2023)“…The second abundant micronutrient, zinc, is attracting more and more attention for it performs essential functions in living organisms and bears close…”
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Radiotherapy-exposed CD8+ and CD4+ neoantigens enhance tumor control
Published in The Journal of clinical investigation (01-03-2021)“…Neoantigens generated by somatic nonsynonymous mutations are key targets of tumor-specific T cells, but only a small number of mutations predicted to be…”
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Asymmetric functions of a binuclear metal center within the transport pathway of a human zinc transporter ZIP4
Published in The FASEB journal (01-01-2020)“…Metal clusters are exploited by numerous metalloenzymes for catalysis, but it is not common to utilize a metal cluster for substrate transport across membrane…”
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Molecular Basis of Zinc-Dependent Endocytosis of Human ZIP4 Transceptor
Published in Cell reports (Cambridge) (28-04-2020)“…Nutrient transporters can be rapidly removed from the cell surface via substrate-stimulated endocytosis as a way to control nutrient influx, but the molecular…”
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Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing
Published in Nature medicine (01-07-2017)“…A protocol based on chemical modulation of WNT activity is used to efficiently generate colonic organoids that recapitulate the molecular features of human…”
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