Search Results - "Zhang, Sherry X"
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Substratum stiffness signals through integrin-linked kinase and β1-integrin to regulate midbody proteins and abscission during EMT
Published in Molecular biology of the cell (19-08-2021)“…Abscission is the final stage of cytokinesis during which the parent cell physically separates to yield two identical daughters. Failure of abscission results…”
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Substratum stiffness tunes membrane voltage in mammary epithelial cells
Published in Journal of cell science (01-07-2021)“…Membrane voltage (Vm) plays a critical role in the regulation of several cellular behaviors, including proliferation, apoptosis and phenotypic plasticity. Many…”
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Matrix degradation and cell proliferation are coupled to promote invasion and escape from an engineered human breast microtumor
Published in Integrative biology (Cambridge) (03-02-2021)“…Metastasis, the leading cause of mortality in cancer patients, depends upon the ability of cancer cells to invade into the extracellular matrix that surrounds…”
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4
Substratum stiffness tunes membrane voltage in mammary epithelial cells
Published in Journal of cell science (12-07-2021)“…Membrane voltage ( V m ) plays a critical role in the regulation of several cellular behaviors, including proliferation, apoptosis and phenotypic plasticity…”
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Abstract 5914: A soft microenvironment protects from failure of midbody abscission and multinucleation downstream of EMT initiators
Published in Cancer research (Chicago, Ill.) (01-07-2017)“…Abstract This study investigates how increased stiffness of the tumor microenvironment can induce cellular multinucleation, an easily observable marker of…”
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A comprehensive study of long-term skeletal changes after spinal cord injury in adult rats
Published in Bone research (27-10-2015)“…Spinal cord injury(SCI)-induced bone loss represents the most severe osteoporosis with no effective treatment.Past animal studies have focused primarily on…”
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