Search Results - "Zhang, Saijuan"

Safety and pharmacokinetics of islatravir subdermal implant for HIV-1 pre-exposure prophylaxis: a randomized, placebo-controlled phase 1 trial by Matthews, Randolph P., Patel, Munjal, Barrett, Stephanie E., Haspeslagh, Liesbeth, Reynders, Tom, Zhang, Saijuan, Rottey, Sylvie, Goodey, Adrian, Vargo, Ryan C., Grobler, Jay A., Stoch, S. Aubrey, Iwamoto, Marian

“…Islatravir (MK-8591) is a highly potent type 1 human immunodeficiency virus (HIV-1) nucleoside reverse transcriptase translocation inhibitor with a long…”
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Safety and Pharmacokinetics of Once-Daily Multiple-Dose Administration of Islatravir in Adults Without HIV by Matthews, Randolph P., Jackson Rudd, Deanne, Zhang, Saijuan, Fillgrove, Kerry L., Sterling, Laura M., Grobler, Jay A., Vargo, Ryan C., Stoch, S. Aubrey, Iwamoto, Marian

“…Islatravir (MK-8591) is a novel nucleoside analog in development for the treatment and prevention of HIV-1 infection. Islatravir has potent antiviral activity…”
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Single Oral Doses of MK-8507, a Novel Non-Nucleoside Reverse Transcriptase Inhibitor, Suppress HIV-1 RNA for a Week by Schürmann, Dirk, Jackson Rudd, Deanne, Schaeffer, Andrea, De Lepeleire, Inge, Friedman, Evan J., Robberechts, Martine, Zhang, Saijuan, Liu, Yang, Kandala, Bhargava, Keicher, Christian, Däumer, Martin, Hofmann, Jörg, Grobler, Jay A., Stoch, S. Aubrey, Iwamoto, Marian, Ankrom, Wendy

“…MK-8507 is a novel HIV-1 non-nucleoside reverse transcriptase inhibitor being developed for treatment of HIV-1 infection. MK-8507 has high antiviral potency in…”
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Fitting a bivariate measurement error model for episodically consumed dietary components by Zhang, Saijuan, Krebs-Smith, Susan M, Midthune, Douglas, Perez, Adriana, Buckman, Dennis W, Kipnis, Victor, Freedman, Laurence S, Dodd, Kevin W, Carroll, Raymond J

“…There has been great public health interest in estimating usual, i.e., long-term average, intake of episodically consumed dietary components that are not…”
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A Phase 1 Trial to Evaluate the Relationship Between Fluoride Intake and Urinary Fluoride Excretion in Healthy Participants by Gillespie, Gillian, Jackson Rudd, Deanne, Zhang, Saijuan, Schaeffer, Andrea, Tomek, Charles, Larson, Patrick, Stoch, S. Aubrey, Iwamoto, Marian

“…Chronic overexposure to fluoride can have deleterious effects in the musculoskeletal system. Some fluorine‐containing therapeutics, such as voriconazole,…”
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Fluoride Pharmacokinetics in Urine and Plasma Following Multiple Doses of MK‐8507, an Investigational, Oral, Once‐Weekly Nonnucleoside Reverse Transcriptase Inhibitor by Gillespie, Gillian, Jackson Rudd, Deanne, Zhang, Saijuan, Schaeffer, Andrea, Tomek, Charles, Larson, Patrick, Stoch, S. Aubrey, Iwamoto, Marian

“…MK‐8507 is an investigational HIV‐1 nonnucleoside reverse transcriptase inhibitor being developed for the treatment of HIV‐1 infection. MK‐8507 contains 2…”
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Single oral doses of MK-8507, a novel non-nucleoside reverse transcriptase inhibitor, suppress HIV-1 RNA for a week by Schürmann, Dirk, Rudd, Deanne Jackson, Schaeffer, Andrea, De Lepeleire, Inge, Friedman, Evan J., Robberechts, Martine, Zhang, Saijuan, Liu, Yang, Kandala, Bhargava, Keicher, Christian, Däumer, Martin, Hofmann, Jörg, Grobler, Jay A., Stoch, S. Aubrey, Iwamoto, Marian, Ankrom, Wendy

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Safety, pharmacokinetics, and antiretroviral activity of islatravir (ISL, MK-8591), a novel nucleoside reverse transcriptase translocation inhibitor, following single-dose administration to treatment-naive adults infected with HIV-1: an open-label, phase 1b, consecutive-panel trial by Schürmann, Dirk, Rudd, Deanne Jackson, Zhang, Saijuan, De Lepeleire, Inge, Robberechts, Martine, Friedman, Evan, Keicher, Christian, Hüser, Andreas, Hofmann, Jörg, Grobler, Jay A, Stoch, S Aubrey, Iwamoto, Marian, Matthews, Randolph P

“…Islatravir (also known as ISL and MK-8591) is a unique nucleoside reverse transcriptase translocation inhibitor in clinical development for treatment of people…”
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A Phase 1 Study to Evaluate the Drug Interaction Between Islatravir (MK-8591) and Doravirine in Adults Without HIV by Matthews, Randolph P., Jackson Rudd, Deanne, Fillgrove, Kerry L., Zhang, Saijuan, Tomek, Charles, Stoch, S. Aubrey, Iwamoto, Marian

“…Background and Objectives Islatravir (MK-8591) is a novel nucleoside analogue in development for the treatment and prevention of HIV-1 infection. Doravirine is…”
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A phase 1, open‐label study to evaluate the drug interaction between islatravir (MK‐8591) and the oral contraceptive levonorgestrel/ethinyl estradiol in healthy adult females by Ankrom, Wendy, Jackson Rudd, Deanne, Zhang, Saijuan, Fillgrove, Kerry L., Gravesande, Kezia N., Matthews, Randolph P., Brimhall, Darin, Stoch, S. Aubrey, Iwamoto, Marian N.

“…Introduction Hormonal contraceptives are among the most effective forms of reversible contraception, but many other compounds, including some antiretrovirals,…”
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Lack of a Clinically Meaningful Drug Interaction Between the HIV‐1 Antiretroviral Agents Islatravir, Dolutegravir, and Tenofovir Disoproxil Fumarate by Rudd, Deanne Jackson, Zhang, Saijuan, Fillgrove, Kerry L., Fox‐Bosetti, Sabrina, Matthews, Randolph P., Friedman, Evan, Armas, Danielle, Stoch, S. Aubrey, Iwamoto, Marian

“…Islatravir, an investigational nucleoside reverse transcriptase translocation inhibitor, is in clinical development for the treatment and prevention of HIV‐1…”
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A NEW MULTIVARIATE MEASUREMENT ERROR MODEL WITH ZERO-INFLATED DIETARY DATA, AND ITS APPLICATION TO DIETARY ASSESSMENT by Zhang, Saijuan, Midthune, Douglas, Guenther, Patricia M., Krebs-Smith, Susan M., Kipnis, Victor, Dodd, Kevin W., Buckman, Dennis W., Tooze, Janet A., Freedman, Laurence, Carroll, Raymond J.

“…In the United States the preferred method of obtaining dietary intake data is the 24-hour dietary recall, yet the measure of most interest is usual or longterm…”
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Optimized human factor IX expression cassettes for hepaticdirected gene therapy of hemophilia B by Ru Zhang Qiang Wang Lin Zhang Saijuan Chen

“…Gene therapy provides a potential cure for hemophilia B, and significant progress has been achieved in liver-directed gene transfer mediated by…”
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Intake_epis_food(): An R Function for Fitting a Bivariate Nonlinear Measurement Error Model to Estimate Usual and Energy Intake for Episodically Consumed Foods by Pérez, Adriana, Zhang, Saijuan, Kipnis, Victor, Midthune, Douglas, Freedman, Laurence S, Carroll, Raymond J

“…We consider a Bayesian analysis using WinBUGS to estimate the distribution of usual intake for episodically consumed foods and energy (calories). The model…”
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Predicting surgical case durations using ill-conditioned CPT code matrix by Li, Ying, Zhang, Saijuan, Baugh, Reginald F., Huang, Jianhua Z.

“…Efficient utilization of existing resources is crucial for cost containment in medical institutions. Accurately predicting surgery duration will improve the…”
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A new multivariate measurement error model with zero-inflated dietary data, and its application to dietary assessment by Zhang, Saijuan, Carroll, Raymond J, Midthune, Douglas, Guenther, Patricia M, Krebs-Smith, Susan M, Kipnis, Victor, Dodd, Kevin W, Buckman, Dennis W, Tooze, Janet A, Freedman, Laurence

“…Annals of Applied Statistics 2011, Vol. 5, No. 2B, 1456-1487 In the United States the preferred method of obtaining dietary intake data is the 24-hour dietary…”
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