Search Results - "Zhang, Qifang"

Activation of NLRP3 Inflammasome and Onset of Alzheimer's Disease by Bai, Hua, Zhang, Qifang

“…The nucleotide-binding domain leucine-rich repeat and pyrin domain containing receptor protein 3 (NLRP3) is an important pattern recognition receptor in human…”
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Cathepsin B links oxidative stress to the activation of NLRP3 inflammasome by Bai, Hua, Yang, Bo, Yu, Wenfeng, Xiao, Yan, Yu, Dejun, Zhang, Qifang

“…Oxidative stress-mediated activation of NLRP3 inflammasome in microglia is critical in the development of neurodegerative diseases such as Alzheimer's disease…”
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TLR9-Targeted STAT3 Silencing Abrogates Immunosuppressive Activity of Myeloid-Derived Suppressor Cells from Prostate Cancer Patients by Hossain, Dewan M S, Pal, Sumanta K, Moreira, Dayson, Duttagupta, Priyanka, Zhang, Qifang, Won, Haejung, Jones, Jeremy, D'Apuzzo, Massimo, Forman, Stephen, Kortylewski, Marcin

“…Recent advances in immunotherapy of advanced human cancers underscored the need to address and eliminate tumor immune evasion. The myeloid-derived suppressor…”
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Fluctuation of puncture force in medical needle puncture of soft solids by Liu, Junjie, Jiang, Zhouhu, Hu, Nan, Zhang, Qifang, Li, Yuhong, Zhong, Danming, Wang, Peng

“…Puncture of soft solids involves the process of piercing through a soft solid material using a sharp object, which is of great interest in biomedical and…”
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Role of N4-acetylcytidine for continuously activating NLRP3 inflammosome by HMGB1 pathway in microglia by Bai, Hua, Zhang, Qifang

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Glioma-targeted delivery of exosome-encapsulated antisense oligonucleotides using neural stem cells by Adamus, Tomasz, Hung, Chia-Yang, Yu, Chunsong, Kang, Elaine, Hammad, Mohamed, Flores, Linda, Nechaev, Sergey, Zhang, Qifang, Gonzaga, Joanna Marie, Muthaiyah, Kokilah, Swiderski, Piotr, Aboody, Karen S., Kortylewski, Marcin

“…Tropism of neural stem cells (NSCs) to hypoxic tumor areas provides an opportunity for the drug delivery. Here, we demonstrate that NSCs effectively transport…”
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Mitochondrial-targeted Signal Transducer and Activator of Transcription 3 (STAT3) Protects against Ischemia-induced Changes in the Electron Transport Chain and the Generation of Reactive Oxygen Species by Szczepanek, Karol, Chen, Qun, Derecka, Marta, Salloum, Fadi N., Zhang, Qifang, Szelag, Magdalena, Cichy, Joanna, Kukreja, Rakesh C., Dulak, Jozef, Lesnefsky, Edward J., Larner, Andrew C.

“…Expression of the STAT3 transcription factor in the heart is cardioprotective and decreases the levels of reactive oxygen species. Recent studies indicate that…”
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Function of Mitochondrial Stat3 in Cellular Respiration by Wegrzyn, Joanna, Potla, Ramesh, Chwae, Yong-Joon, Sepuri, Naresh B.V, Zhang, Qifang, Koeck, Thomas, Derecka, Marta, Szczepanek, Karol, Szelag, Magdalena, Gornicka, Agnieszka, Moh, Akira, Moghaddas, Shadi, Chen, Qun, Bobbili, Santha, Cichy, Joanna, Dulak, Jozef, Baker, Darren P, Wolfman, Alan, Stuehr, Dennis, Hassan, Medhat O, Fu, Xin-Yuan, Avadhani, Narayan, Drake, Jennifer I, Fawcett, Paul, Lesnefsky, Edward J, Larner, Andrew C

“…Cytokines such as interleukin-6 induce tyrosine and serine phosphorylation of Stat3 that results in activation of Stat3-responsive genes. We provide evidence…”
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A novel mycovirus infecting Aspergillus nidulans that is closely related to viruses in a new genus of the family Partitiviridae by Jiang, Yinhui, Yang, Bi, Liu, Jiayu, Wang, Qinrong, Zhang, Qifang, Yu, Wenfeng, Hsiang, Tom

“…The bisegmented genome of a novel double-stranded (ds) RNA mycovirus, named “Aspergillus nidulans partitivirus 1” (AnPV1), isolated from the fungus Aspergillus…”
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Complete genome sequence of a novel victorivirus infecting Aspergillus niger by Jiang, Yinhui, Liu, Xiang, Yang, Bi, Tian, Xun, Liu, Jiayu, Wang, Qinrong, Zhang, Qifang, Yu, Wenfeng, Qi, Xiaolan, Hsiang, Tom

“…Aspergillus niger is an important filamentous phytopathogenic fungus with a broad host range. A novel double-stranded (ds) RNA mycovirus, named A spergillus n…”
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BMSC cells alleviate liver injury induced by ulcerative colitis via repairing the intestinal-liver barrier and activating hepatocyte growth factor by Deng, Zhejun, Meng, Yunchao, Zhao, Lei, Luo, Wenjie, Zhang, Jing, Hu, Jie, Jiang, Haixing, Zhang, Qifang

“…Ulcerative colitis (UC), which belongs to inflammatory bowel diseases (IBD), frequently induces liver inflammation and injury. Previous studies have proved that…”
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Leukemia cell–targeted STAT3 silencing and TLR9 triggering generate systemic antitumor immunity by Hossain, Dewan Md Sakib, Dos Santos, Cedric, Zhang, Qifang, Kozlowska, Anna, Liu, Hongjun, Gao, Chan, Moreira, Dayson, Swiderski, Piotr, Jozwiak, Agnieszka, Kline, Justin, Forman, Stephen, Bhatia, Ravi, Kuo, Ya-Huei, Kortylewski, Marcin

“…Signal transducer and activator of transcription 3 (STAT3) is an oncogene and immune checkpoint commonly activated in cancer cells and in tumor-associated…”
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TLR9-mediated siRNA delivery for targeting of normal and malignant human hematopoietic cells in vivo by Zhang, Qifang, Hossain, Dewan Md Sakib, Nechaev, Sergey, Kozlowska, Anna, Zhang, Wang, Liu, Yong, Kowolik, Claudia M., Swiderski, Piotr, Rossi, John J., Forman, Stephen, Pal, Sumanta, Bhatia, Ravi, Raubitschek, Andrew, Yu, Hua, Kortylewski, Marcin

“…STAT3 operates in both cancer cells and tumor-associated immune cells to promote cancer progression. As a transcription factor, it is a highly desirable but…”
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Heparanase-1-induced shedding of heparan sulfate from syndecan-1 in hepatocarcinoma cell facilitates lymphatic endothelial cell proliferation via VEGF-C/ERK pathway by Yu, Shengjin, Lv, Huiming, Zhang, He, Jiang, Yu, Hong, Yu, Xia, Rongjun, Zhang, Qifang, Ju, Weiwei, Jiang, Lili, Ou, Geng, Zhang, Jinhui, Wang, Shujing, Zhang, Jianing

“…Heparanase-1/syndecan-1 axis plays critical roles in tumorigenesis and development. The main mechanism includes heparanase-1 (HPA-1) degrades the heparan…”
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N4-acetylcytidine is required for sustained NLRP3 inflammasome activation via HMGB1 pathway in microglia by Duan, JuanJuan, Zhang, Qifang, Hu, Xiaohong, Lu, Deqin, Yu, Wenfeng, Bai, Hua

“…Persistent inflammasome activation contributes to chronic, low grade inflammation. However, it is unclear how the inflammasome activation is sustained after…”
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Angiotensin II Decreases Endothelial Nitric Oxide Synthase Phosphorylation via AT1R Nox/ROS/PP2A Pathway by Ding, Jing, Yu, Min, Jiang, Juncai, Luo, Yanbei, Zhang, Qian, Wang, Shengnan, Yang, Fei, Wang, Alei, Wang, Lingxiao, Zhuang, Mei, Wu, Shan, Zhang, Qifang, Xia, Yong, Lu, Deqin

“…Increasing evidences suggest that angiotensin (Ang) II participates in the pathogenesis of endothelial dysfunction (ED) through multiple signaling pathways,…”
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A Satellite dsRNA Attenuates the Induction of Helper Virus-Mediated Symptoms in Aspergillus flavus by Jiang, Yinhui, Yang, Bi, Liu, Xiang, Tian, Xun, Wang, Qinrong, Wang, Bi, Zhang, Qifang, Yu, Wenfeng, Qi, Xiaolan, Jiang, Yanping, Hsiang, Tom

“…Aspergillus flavus is an important fungal pathogen of animals and plants. Previously, we reported a novel partitivirus, Aspergillus flavus partitivirus 1…”
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The cwp66 Gene Affects Cell Adhesion, Stress Tolerance, and Antibiotic Resistance in Clostridioides difficile by Zhou, Qingshuai, Rao, Fengqin, Chen, Zhenghong, Cheng, Yumei, Zhang, Qifang, Zhang, Jie, Guan, Zhizhong, He, Yan, Yu, Wenfeng, Cui, Guzhen, Qi, Xiaolan, Hong, Wei

“…Clostridioides difficile is a Gram-positive, spore-forming anaerobic bacteria that is one of the leading causes of antibiotic-associated diarrhea. The cell…”
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Tyk2 and Stat3 Regulate Brown Adipose Tissue Differentiation and Obesity by Derecka, Marta, Gornicka, Agnieszka, Koralov, Sergei B., Szczepanek, Karol, Morgan, Magdalena, Raje, Vidisha, Sisler, Jennifer, Zhang, Qifang, Otero, Dennis, Cichy, Joanna, Rajewsky, Klaus, Shimoda, Kazuya, Poli, Valeria, Strobl, Birgit, Pellegrini, Sandra, Harris, Thurl E., Seale, Patrick, Russell, Aaron P., McAinch, Andrew J., O’Brien, Paul E., Keller, Susanna R., Croniger, Colleen M., Kordula, Tomasz, Larner, Andrew C.

“…Mice lacking the Jak tyrosine kinase member Tyk2 become progressively obese due to aberrant development of Myf5+ brown adipose tissue (BAT). Tyk2 RNA levels in…”
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FOXP4-AS1 Inhibits Papillary Thyroid Carcinoma Proliferation and Migration Through the AKT Signaling Pathway by Luo, Xue, Gao, Qingjun, Zhou, Tian, Tang, Rui, Zhao, Yu, Zhang, Qifang, Wang, Nanpeng, Ye, Hui, Chen, Xinghong, Chen, Song, Tang, Wenli, Zhao, Daiwei

“…Papillary thyroid carcinoma, also known as PTC, is one of the commonest malignancies in the endocrine system. Long non-coding RNAs (lncRNAs) in PTC could…”
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