Search Results - "Zhang, Nu"
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CD8 + Regulatory T Cell - A Mystery to Be Revealed
Published in Frontiers in immunology (18-08-2021)“…Regulatory T cells (Treg) are essential to maintain immune homeostasis and prevent autoimmune disorders. While the function and molecular regulation of Foxp3…”
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Transforming growth factor-β signaling is constantly shaping memory T-cell population
Published in Proceedings of the National Academy of Sciences - PNAS (01-09-2015)“…The long-term maintenance of memory T cells is essential for successful vaccines. Both the quantity and the quality of the memory T-cell population must be…”
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A novel protein encoded by the circular form of the SHPRH gene suppresses glioma tumorigenesis
Published in Oncogene (01-03-2018)“…Circular RNAs (circRNAs) are recognized as functional non-coding transcripts in eukaryotic cells. Recent evidence has indicated that even though circRNAs are…”
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A peptide encoded by circular form of LINC-PINT suppresses oncogenic transcriptional elongation in glioblastoma
Published in Nature communications (26-10-2018)“…Circular RNAs (circRNAs) are a large class of transcripts in the mammalian genome. Although the translation of circRNAs was reported, additional coding…”
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Lymphoid tissue residency: A key to understand Tcf-1 + PD-1 + T cells
Published in Frontiers in immunology (07-12-2022)“…During chronic antigen exposure, a subset of exhausted CD8 T cells differentiate into stem cell-like or progenitor-like T cells expressing both transcription…”
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Editorial: TGF-β and T cell biology
Published in Frontiers in immunology (05-09-2023)Get full text
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A novel tumor suppressor protein encoded by circular AKT3 RNA inhibits glioblastoma tumorigenicity by competing with active phosphoinositide-dependent Kinase-1
Published in Molecular cancer (30-08-2019)“…The RTK/PI3K/AKT pathway plays key roles in the development and progression of many cancers, including GBM. As a regulatory molecule and a potential drug…”
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A novel protein encoded by circular SMO RNA is essential for Hedgehog signaling activation and glioblastoma tumorigenicity
Published in Genome Biology (14-01-2021)“…Aberrant activation of the Hedgehog pathway drives tumorigenesis of many cancers, including glioblastoma. However, the sensitization mechanism of the G…”
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Circular HER2 RNA positive triple negative breast cancer is sensitive to Pertuzumab
Published in Molecular cancer (11-09-2020)“…Abstract Background Triple negative breast cancer (TNBC) remains the most challenging breast cancer subtype so far. Specific therapeutic approaches have rarely…”
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TGF-β Controls the Formation of Kidney-Resident T Cells via Promoting Effector T Cell Extravasation
Published in The Journal of immunology (1950) (15-01-2017)“…Tissue-resident memory T (T ) cells, a population of noncirculating memory T cells, are one of the essential components of immunological memory in both mouse…”
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Dicer controls CD8⁺ T-cell activation, migration, and survival
Published in Proceedings of the National Academy of Sciences - PNAS (14-12-2010)“…The RNaseIII enzyme Dicer is required for mature microRNA production. Although extensive investigation has been carried out to determine the role of…”
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CircCD44 plays oncogenic roles in triple-negative breast cancer by modulating the miR-502-5p/KRAS and IGF2BP2/Myc axes
Published in Molecular cancer (25-10-2021)“…Emerging studies have revealed the potent functions of circRNAs in breast cancer tumorigenesis. However, the biogenesis, biofunction and mechanism of circRNAs…”
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Editorial: Resolution and regeneration of inflammation in lung and brain disorders
Published in Frontiers in immunology (03-10-2023)Get full text
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14
Circular RNAs and human glioma
Published in Cancer biology & medicine (01-02-2019)“…As a newly discovered type of RNA, circular RNAs (circRNAs) are widespread throughout the eukaryotic genome. The expression of circRNAs is regulated by both…”
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Into the storm: the imbalance in the yin-yang immune response as the commonality of cytokine storm syndromes
Published in Frontiers in immunology (10-09-2024)“…There is a continuous cycle of activation and contraction in the immune response against pathogens and other threats to human health in life. This intrinsic…”
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Circular EZH2-encoded EZH2-92aa mediates immune evasion in glioblastoma via inhibition of surface NKG2D ligands
Published in Nature communications (15-08-2022)“…Glioblastoma (GBM) is a highly aggressive primary brain tumour and is resistant to nearly all available treatments, including natural killer (NK) cell…”
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Corrigendum: Into the storm: the imbalance in the yin-yang immune response as the commonality of cytokine storm syndromes
Published in Frontiers in immunology (01-10-2024)“…[This corrects the article DOI: 10.3389/fimmu.2024.1448201.]…”
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Comprehensive understanding of anchorage-independent survival and its implication in cancer metastasis
Published in Cell death & disease (18-06-2021)“…Detachment is the initial and critical step for cancer metastasis. Only the cells that survive from detachment can develop metastases. Following the disruption…”
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Circular RNA encoded MET variant promotes glioblastoma tumorigenesis
Published in Nature communications (25-07-2023)“…Activated by its single ligand, hepatocyte growth factor (HGF), the receptor tyrosine kinase MET is pivotal in promoting glioblastoma (GBM) stem cell…”
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Identification of TNFAIP6 as a hub gene associated with the progression of glioblastoma by weighted gene co‐expression network analysis
Published in IET systems biology (01-09-2022)“…This study aims to discover the genetic modules that distinguish glioblastoma multiforme (GBM) from low‐grade glioma (LGG) and identify hub genes. A…”
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