Search Results - "Zhang, Ningping"
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Adding pegylated interferon to entecavir for hepatitis B e antigen–positive chronic hepatitis B: A multicenter randomized trial (ARES study)
Published in Hepatology (Baltimore, Md.) (01-05-2015)“…Entecavir (ETV) is a potent inhibitor of hepatitis B viral replication, but long‐term therapy may be required. We investigated whether adding on pegylated…”
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Tofacitinib for the treatment of immune-related adverse events in cancer immunotherapy: a multi-center observational study
Published in Journal of translational medicine (29-08-2024)“…Treatment strategy against immune-related adverse events (irAEs) induced by immune checkpoint inhibitors (ICIs) frequently requires other immunosuppressive…”
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3
CD86 + /CD206 + tumor-associated macrophages predict prognosis of patients with intrahepatic cholangiocarcinoma
Published in PeerJ (San Francisco, CA) (22-01-2020)“…As the main cellular ingredients of tumor microenvironment, tumor-associated macrophages (TAMs) play a vital role in tumor development and progression. Recent…”
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4
CAPS1 Suppresses Tumorigenesis in Cholangiocarcinoma
Published in Digestive diseases and sciences (01-04-2020)“…Background CAPS1 (calcium-dependent activator protein for secretion) is a multi-domain protein involved in regulating exocytosis of synaptic vesicles and…”
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Clinical characteristics and prognosis of liver injury induced by immune checkpoint inhibitors in patients with malignancies: A real‐world retrospective study
Published in British journal of clinical pharmacology (01-11-2024)“…Aims Programmed cell death receptor (ligand)‐1 inhibitors (PD‐(L)1), as the preferred immunotherapy, have been widely used in the Chinese mainland and…”
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6
Risk Factors of Immune-Mediated Hepatotoxicity Induced by Immune Checkpoint Inhibitors in Cancer Patients: A Systematic Review and Meta-Analysis
Published in Current oncology (Toronto) (13-11-2024)“…Immune checkpoint inhibitors (ICIs) significantly improve survival, while immune-mediated hepatotoxicity (IMH) has been reported. To evaluate the incidence and…”
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M2‐polarized tumor‐associated macrophages promote epithelial‐mesenchymal transition via activation of the AKT3/PRAS40 signaling pathway in intrahepatic cholangiocarcinoma
Published in Journal of cellular biochemistry (01-04-2020)“…Tumor‐associated macrophages (TAMs) have been considered as a major component of the tumor microenvironment. However, the crosstalk between M2‐polarized…”
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Dampened VEPH1 activates mTORC1 signaling by weakening the TSC1/TSC2 association in hepatocellular carcinoma
Published in Journal of hepatology (01-12-2020)“…Abnormal activation of mTORC1 signaling occurs at high frequency in hepatocellular carcinoma (HCC). However, the underlying causes of this aberrant activation…”
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Morphology of immune-mediated hepatitis: A comparison between immune checkpoint inhibitor therapy and combined immune checkpoint inhibitor/anti-angiogenic therapy
Published in Annals of diagnostic pathology (01-02-2024)“…The combination of immune checkpoint inhibitors (ICIs) with anti-angiogenic drugs has shown promising anticancer effects. However, ICIs can trigger…”
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10
Nucleos(t)ide Analogues Only Induce Temporary Hepatitis B e Antigen Seroconversion in Most Patients With Chronic Hepatitis B
Published in Gastroenterology (New York, N.Y. 1943) (01-08-2010)“…Background & Aims Inconsistencies in results and guideline recommendations regarding the durability of nucleos(t)ide analogue-induced hepatitis B e antigen…”
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Integrated in silico‐in vitro analysis of systematic kinase gatekeeper mutation effects on pan‐kinase inhibitors in targeted liver cancer therapy
Published in Journal of the Chinese Chemical Society (Taipei) (01-04-2021)“…Kinase‐targeted therapy has been established as a widely used strategy to treat liver cancer. However, a number of kinase gatekeeper mutations are clinically…”
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12
Photoacoustic venous blood pressure sensing: a feasibility study
Published in 2023 IEEE International Ultrasonics Symposium (IUS) (03-09-2023)“…Portal hypertension (PH) is defined as high blood pressure in the splanchnic venous system, which is the driver of life-threatening complications. Currently…”
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