Search Results - "Zhang, Maolei"
-
1
A novel protein encoded by the circular form of the SHPRH gene suppresses glioma tumorigenesis
Published in Oncogene (01-03-2018)“…Circular RNAs (circRNAs) are recognized as functional non-coding transcripts in eukaryotic cells. Recent evidence has indicated that even though circRNAs are…”
Get full text
Journal Article -
2
Circular RNA-encoded oncogenic E-cadherin variant promotes glioblastoma tumorigenicity through activation of EGFR–STAT3 signalling
Published in Nature cell biology (01-03-2021)“…Activated EGFR signalling drives tumorigenicity in 50% of glioblastoma (GBM). However, EGFR-targeting therapy has proven ineffective in treating patients with…”
Get full text
Journal Article -
3
A peptide encoded by circular form of LINC-PINT suppresses oncogenic transcriptional elongation in glioblastoma
Published in Nature communications (26-10-2018)“…Circular RNAs (circRNAs) are a large class of transcripts in the mammalian genome. Although the translation of circRNAs was reported, additional coding…”
Get full text
Journal Article -
4
A novel tumor suppressor protein encoded by circular AKT3 RNA inhibits glioblastoma tumorigenicity by competing with active phosphoinositide-dependent Kinase-1
Published in Molecular cancer (30-08-2019)“…The RTK/PI3K/AKT pathway plays key roles in the development and progression of many cancers, including GBM. As a regulatory molecule and a potential drug…”
Get full text
Journal Article -
5
A novel protein encoded by circular SMO RNA is essential for Hedgehog signaling activation and glioblastoma tumorigenicity
Published in Genome Biology (14-01-2021)“…Aberrant activation of the Hedgehog pathway drives tumorigenesis of many cancers, including glioblastoma. However, the sensitization mechanism of the G…”
Get full text
Journal Article -
6
Circular HER2 RNA positive triple negative breast cancer is sensitive to Pertuzumab
Published in Molecular cancer (11-09-2020)“…Abstract Background Triple negative breast cancer (TNBC) remains the most challenging breast cancer subtype so far. Specific therapeutic approaches have rarely…”
Get full text
Journal Article -
7
Circular EZH2-encoded EZH2-92aa mediates immune evasion in glioblastoma via inhibition of surface NKG2D ligands
Published in Nature communications (15-08-2022)“…Glioblastoma (GBM) is a highly aggressive primary brain tumour and is resistant to nearly all available treatments, including natural killer (NK) cell…”
Get full text
Journal Article -
8
Circular RNA encoded MET variant promotes glioblastoma tumorigenesis
Published in Nature communications (25-07-2023)“…Activated by its single ligand, hepatocyte growth factor (HGF), the receptor tyrosine kinase MET is pivotal in promoting glioblastoma (GBM) stem cell…”
Get full text
Journal Article -
9
Correction: A novel tumor suppressor protein encoded by circular AKT3 RNA inhibits glioblastoma tumorigenicity by competing with active phosphoinositide-dependent Kinase-1
Published in Molecular cancer (07-06-2022)“…Mol Cancer 18, 131 (2019) https://doi.org/10.1186/s12943-019-1056-5 Following publication of the original article [1], errors were identified in the images…”
Get full text
Journal Article -
10
Correction to: A novel tumor suppressor protein encoded by circular AKT3 RNA inhibits glioblastoma tumorigenicity by competing with active phosphoinositide-dependent Kinase-1
Published in Molecular cancer (29-10-2019)“…In the published article [1], an error was noticed in Fig. 6B. The western blot results were reversed between the overexpression group and the knockdown group…”
Get full text
Journal Article -
11
Novel Role of FBXW7 Circular RNA in Repressing Glioma Tumorigenesis
Published in JNCI : Journal of the National Cancer Institute (01-03-2018)“…Circular RNAs (circRNAs) are RNA transcripts that are widespread in the eukaryotic genome. Recent evidence indicates that circRNAs play important roles in…”
Get full text
Journal Article -
12
Rolling-translated EGFR variants sustain EGFR signaling and promote glioblastoma tumorigenicity
Published in Neuro-oncology (Charlottesville, Va.) (05-05-2021)“…Abstract Background Aberrant epidermal growth factor receptor (EGFR) activation is observed in over 50% of cases of adult glioblastoma (GBM). Nevertheless,…”
Get full text
Journal Article -
13
Understanding vehicles commuting pattern based on license plate recognition data
Published in Transportation research. Part C, Emerging technologies (01-07-2021)“…•Commuting behavior based on license plate recognition (LPR) data were analyzed based on both time and space perspectives.•The fast search and find of density…”
Get full text
Journal Article -
14
On-Demand Greenwave for Emergency Vehicles in a Time-Varying Road Network With Uncertainties
Published in IEEE transactions on intelligent transportation systems (01-07-2020)“…The response time of emergency vehicles (EV) is critical to saving lives. In this paper, we address the two challenges to the reduction of EV response time: 1)…”
Get full text
Journal Article -
15
Response to H. Chen, Y. Liu, P. Li, and D. Zhu
Published in JNCI : Journal of the National Cancer Institute (01-04-2019)Get full text
Journal Article -
16
An Upstream Open Reading Frame in Phosphatase and Tensin Homolog Encodes a Circuit Breaker of Lactate Metabolism
Published in Cell metabolism (05-01-2021)“…The metabolic role of micropeptides generated from untranslated regions remains unclear. Here we describe MP31, a micropeptide encoded by the upstream open…”
Get full text
Journal Article -
17
Non-singular Terminal Sliding Mode Control for Pneumatic System Based on Extended State Observer
Published in 2022 41st Chinese Control Conference (CCC) (25-07-2022)“…To suppress the compound disturbance of internal parameter perturbation and external disturbance of pneumatic system, a non-singular terminal sliding mode…”
Get full text
Conference Proceeding -
18
A novel protein RASON encoded by a lncRNA controls oncogenic RAS signaling in KRAS mutant cancers
Published in Cell research (01-01-2023)“…Mutations of the RAS oncogene are found in around 30% of all human cancers yet direct targeting of RAS is still considered clinically impractical except for…”
Get full text
Journal Article -
19
A novel protein CYTB-187AA encoded by the mitochondrial gene CYTB modulates mammalian early development
Published in Cell metabolism (02-07-2024)“…The mitochondrial genome transcribes 13 mRNAs coding for well-known proteins essential for oxidative phosphorylation. We demonstrate here that cytochrome b…”
Get more information
Journal Article -
20
An Upstream Open Reading Frame in Phosphatase and Tensin Homolog Encodes a Circuit Breaker of Lactate Metabolism
Published in Cell metabolism (02-02-2021)Get full text
Journal Article