Search Results - "Zhang, Lianshan"

Examining the Role of Information Behavior in Linking Cancer Risk Perception and Cancer Worry to Cancer Fatalism in China: Cross-Sectional Survey Study by Zhang, Lianshan, Jiang, Shaohai

“…Reducing cancer fatalism is essential because of its detrimental impact on cancer-related preventive behaviors. However, little is known about factors…”
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When Does WeChat Usage Decrease Loneliness? A Panel Study Examining the Moderating Roles of Age and Perceived Network Supportiveness by Zhang, Lianshan, Yang, Xiaodong, Jung, Eun Hwa

“…Moving beyond examining overall social networking site (SNS) use, this study examined the influence of three types of WeChat activities on loneliness,…”
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The more engaging, the more enjoyable? Age matters in predicting perceived enjoyment with different Facebook activities by Zhang, Lianshan, Jung, Eun Hwa

“…Drawing upon uses and gratifications perspectives and socioemotional selectivity theory, this study examined the differences in the use of Facebook features…”
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First Impression Formation Based on Valenced Self-Disclosure in Social Media Profiles by Qin, Yuren, Cho, Hichang, Li, Pengxiang, Zhang, Lianshan

“…This study aims to understand how the valence of self-disclosure (operationalized as the dominantly positive vs. balanced vs. dominantly negative social media…”
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Unimolecular dual incretins maximize metabolic benefits in rodents, monkeys, and humans by Finan, Brian, Ma, Tao, Ottaway, Nickki, Müller, Timo D, Habegger, Kirk M, Heppner, Kristy M, Kirchner, Henriette, Holland, Jenna, Hembree, Jazzminn, Raver, Christine, Lockie, Sarah H, Smiley, David L, Gelfanov, Vasily, Yang, Bin, Hofmann, Susanna, Bruemmer, Dennis, Drucker, Daniel J, Pfluger, Paul T, Perez-Tilve, Diego, Gidda, Jaswant, Vignati, Louis, Zhang, Lianshan, Hauptman, Jonathan B, Lau, Michele, Brecheisen, Mathieu, Uhles, Sabine, Riboulet, William, Hainaut, Emmanuelle, Sebokova, Elena, Conde-Knape, Karin, Konkar, Anish, DiMarchi, Richard D, Tschöp, Matthias H

“…We report the discovery and translational therapeutic efficacy of a peptide with potent, balanced co-agonism at both of the receptors for the incretin hormones…”
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Discovery of a novel RORγ antagonist with skin-restricted exposure for topical treatment of mild to moderate psoriasis by Liu, Suxing, Liu, Dong, Shen, Ru, Li, Di, Hu, Qiyue, Yan, Yinfa, Sun, Jiakang, Zhang, Fengqi, Wan, Hong, Dong, Ping, Feng, Jun, Zhang, Rumin, Li, Jing, Zhang, Lianshan, Tao, Weikang

“…Clinical success of IL-17/IL-23 pathway biologics for the treatment of moderate to severe psoriasis suggests that targeting RORγt, a master regulator for the…”
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Reimagining patient-centric cancer clinical trials: a multi-stakeholder international coalition by Li, Bob T., Daly, Bobby, Gospodarowicz, Mary, Bertagnolli, Monica M., Brawley, Otis W., Chabner, Bruce A., Fashoyin-Aje, Lola, de Claro, R. Angelo, Franklin, Elizabeth, Mills, Jennifer, Legos, Jeff, Kaucic, Karen, Li, Mark, The, Lydia, Hou, Tina, Wu, Ting-Hui, Albrecht, Bjorn, Shao, Yi, Finnegan, Justin, Qian, Jing, Shahidi, Javad, Gasal, Eduard, Tendler, Craig, Kim, Geoffrey, Yan, James, Morrow, Phuong Khanh, Fuchs, Charles S., Zhang, Lianshan, LaCaze, Robert, Oelrich, Stefan, Murphy, Martin J., Pazdur, Richard, Rudd, Kevin, Wu, Yi-Long

“…The Bloomberg New Economy International Cancer Coalition brings together academia, industry, government, patient advocacy and policy think tanks to leverage…”
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Knockdown of thioredoxin-interacting protein ameliorates high glucose-induced epithelial to mesenchymal transition in renal tubular epithelial cells by Wei, Jinying, Shi, Yonghong, Hou, Yanjuan, Ren, Yunzhuo, Du, Chunyang, Zhang, Lianshan, Li, Ying, Duan, Huijun

“…Epithelial to mesenchymal transition (EMT) of tubular cells contributes to the renal accumulation of matrix protein that is associated with diabetic…”
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Fatty Acid-Binding Protein 4 mediates apoptosis via endoplasmic reticulum stress in mesangial cells of diabetic nephropathy by Yao, Fang, Li, Zhen, Ehara, Takashi, Yang, Lin, Wang, Dandan, Feng, Lulu, Zhang, Yiming, Wang, Kun, Shi, Yonghong, Duan, Huijun, Zhang, Lianshan

“…•FABP4 exists in glomeruli, especially in glomerular mesangial cells of human kidney.•Glomerular FABP4 is up-regulated in diabetic nephropathy.•FABP4 mediates…”
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Hepatic expression of cannabinoid receptors CB1 and CB2 correlate with fibrogenesis in patients with chronic hepatitis B by Dai, Erhei, Zhang, Lianshan, Ye, Lihong, Wan, Shiqing, Feng, Lulu, Qi, Qi, Yao, Fang, Li, Zhen

“…Highlights • The expression of cannabinoid receptor 1 (CB1) in activated hepatic stellate cells in biopsy specimens from patients with active fibrosis was…”
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Modulation of Nrf2 expression alters high glucose-induced oxidative stress and antioxidant gene expression in mouse mesangial cells by Li, Hang, Wang, Fuxu, Zhang, Lianshan, Cao, Yanping, Liu, Wei, Hao, Jun, Liu, Qingjuan, Duan, Huijun

“…Reactive oxygen species (ROS) play an important role in the pathogenesis of diabetic nephropathy. Nuclear factor erythroid 2-related factor 2 (Nrf2) can…”
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Discovery of EBI-2511: A Highly Potent and Orally Active EZH2 Inhibitor for the Treatment of Non-Hodgkin’s Lymphoma by Lu, Biao, Shen, Xiaodong, Zhang, Lei, Liu, Dong, Zhang, Caihua, Cao, Jingsong, Shen, Ru, Zhang, Jiayin, Wang, Dan, Wan, Hong, Xu, Zhibin, Ho, Ming-Hsun, Zhang, Minsheng, Zhang, Lianshan, He, Feng, Tao, Weikang

“…A novel series of benzofuran derived EZH2 inhibitors were discovered through a scaffold hopping approach based on the clinical compound of EPZ-6438. Further…”
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3D Numerical Study on Compound Heat Transfer Enhancement of Converging-diverging Tubes Equipped with Twin Twisted Tapes by 洪宇翔 邓先和 张连山

“…The paper presents a 3D numerical simulation of turbulent heat transfer and flow characteristics in converging-diverging tubes （CDs） and converging-diverg）ng…”
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Breaking Barriers: A Dual-Factor Model Unraveling Ageism in Socially Assistive Robot Adoption among Older Chinese Adults by Zhang, Lianshan

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Acute alloxan toxicity causes granulomatous tubulointerstitial nephritis with severe mineralization by Zhang, Lianshan, Terayama, Yui, Nishimoto, Taiki, Kodama, Yasushi, Ozaki, Kiyokazu

“…Alloxan had been recognized as having a direct nephrotoxic effect different from its diabetogenic action. We encountered previously unreported granulomatous…”
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Discovery of EBI-907: A highly potent and orally active B-Raf V600E inhibitor for the treatment of melanoma and associated cancers by Lu, Biao, Cao, Hu, Cao, Jingsong, Huang, Song, Hu, Qiyue, Liu, Dong, Shen, Ru, Shen, Xiaodong, Tao, Weikang, Wan, Hong, Wang, Dan, Yan, Yinfa, Yang, Liuqing, Zhang, Jiayin, Zhang, Lei, Zhang, Lianshan, Zhang, Minsheng

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Discovery of SHR9352: A Highly Potent G Protein-Biased μ‑Opioid Receptor Agonist by Li, Xin, He, Wei, Chen, Yang, Yang, Guimei, Wan, Hong, Zhang, Lei, Hu, Qiyue, Feng, Jun, Zhang, Zhigao, He, Feng, Bai, Chang, Zhang, Lianshan, You, Li, Tao, Weikang

“…Recently, targeting the G protein-biased signaling has emerged as an attractive therapeutic strategy for treating severe acute pain with the potential to…”
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Linking Risk Perception to Breast Cancer Examination Intention in China: Examining an Adapted Cognitive Mediation Model by Zhang, Lianshan, Yang, Xiaodong

“…Drawn upon the cognitive mediation model, this study proposes an adapted model and examines the mechanisms by which Chinese women's risk perception of breast…”
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Linking health information seeking to patient-centered communication and healthy lifestyles: an exploratory study in China by Zhang, Lianshan, Jiang, Shaohai

“…The existing research routinely measures the influence of health information-seeking behavior (HISB) as a whole, which does not capture the complexity and…”
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"I Know News Will Find Me": Examining the Relationship Between the "News-Finds-Me" Perception and COVID-19 Misperceptions by Zhang, Lianshan, Jiang, Shaohai

“…In the current media environment, some individuals have shifted from actively monitoring news toward passively waiting for the media to alert them about news…”
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