Search Results - "Zhang, Kunyu"
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Structurally Dynamic Hydrogels for Biomedical Applications: Pursuing a Fine Balance between Macroscopic Stability and Microscopic Dynamics
Published in Chemical reviews (22-09-2021)“…Owing to their unique chemical and physical properties, hydrogels are attracting increasing attention in both basic and translational biomedical studies…”
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Immunoregulation of macrophages by dynamic ligand presentation via ligand–cation coordination
Published in Nature communications (12-04-2019)“…Macrophages regulate host responses to implants through their dynamic adhesion, release, and activation. Herein, we employ bisphosphonate (BP)-coated gold…”
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Enhanced mechanosensing of cells in synthetic 3D matrix with controlled biophysical dynamics
Published in Nature communications (10-06-2021)“…3D culture of cells in designer biomaterial matrices provides a biomimetic cellular microenvironment and can yield critical insights into cellular behaviours…”
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4
Near-infrared light-controlled regulation of intracellular calcium to modulate macrophage polarization
Published in Biomaterials (01-09-2018)“…Macrophages are multifunctional immune cells with diverse physiological functions such as fighting against infection, influencing progression of pathologies,…”
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Care Preferences Among Chinese Older Adults with Daily Care Needs: Individual and Community Factors
Published in Research on aging (01-03-2021)“…Traditionally, Chinese families have been the primary provider of care for older adults, and older people expected family care. However, along with the…”
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Chain-Shuttling Polymerization at Two Different Scandium Sites: Regio- and Stereospecific "One-Pot" Block Copolymerization of Styrene, Isoprene, and Butadiene
Published in Angewandte Chemie International Edition (09-12-2011)“…To each his own: Copolymerization of styrene and isoprene by catalysts Sc1 (syndiospecific for styrene) and Sc2 (cis‐1,4‐specific for isoprene) with a…”
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Self‐Assembled Injectable Nanocomposite Hydrogels Stabilized by Bisphosphonate‐Magnesium (Mg2+) Coordination Regulates the Differentiation of Encapsulated Stem Cells via Dual Crosslinking
Published in Advanced functional materials (13-09-2017)“…Nanocomposite hydrogels consist of a polymer matrix embedded with nanoparticles (NPs), which provide the hydrogels with unique bioactivities and mechanical…”
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Localized delivery of CRISPR/dCas9 via layer-by-layer self-assembling peptide coating on nanofibers for neural tissue engineering
Published in Biomaterials (01-10-2020)“…The clustered regularly interspaced short palindromic repeat (CRISPR) systems have a wide variety of applications besides precise genome editing. In…”
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Optimized brain extraction for pathological brains (optiBET)
Published in PloS one (16-12-2014)“…The study of structural and functional magnetic resonance imaging data has greatly benefitted from the development of sophisticated and efficient algorithms…”
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10
Surface hydrophobization of hydrogels via interface dynamics-induced network reconfiguration
Published in Nature communications (03-01-2024)“…Effective and easy regulation of hydrogel surface properties without changing the overall chemical composition is important for their diverse applications but…”
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AUV Path Planning Considering Ocean Current Disturbance Based on Cloud Desktop Technology
Published in Sensors (Basel, Switzerland) (29-08-2023)“…In the field of ocean energy detection, Autonomous Underwater Vehicles (AUVs) offer significant advantages in terms of manpower, resource, and energy…”
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Dimer targeting peptide mediated precise and controllable drug delivery by upconversion nanocarriers for breast cancer therapy
Published in Materials & design (01-05-2021)“…Breast cancer is one of the leading causes of cancer-related deaths in women. Chemotherapy remains one of the main clinical treatments for breast cancer…”
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Dynamic and Cell-Infiltratable Hydrogels as Injectable Carrier of Therapeutic Cells and Drugs for Treating Challenging Bone Defects
Published in ACS central science (27-03-2019)“…Biopolymeric hydrogels have been widely used as carriers of therapeutic cells and drugs for biomedical applications. However, most conventional hydrogels…”
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Impaired learning and memory in male mice induced by sodium arsenite was associated with MMP-2/MMP-9-mediated blood-brain barrier disruption and neuronal apoptosis
Published in Ecotoxicology and environmental safety (15-10-2024)“…Arsenic is a widespread environmental contaminant known to accumulate in the brain, leading to cognitive impairment. However, the exact mechanisms by which…”
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An In Situ Reversible Heterodimeric Nanoswitch Controlled by Metal‐Ion–Ligand Coordination Regulates the Mechanosensing and Differentiation of Stem Cells
Published in Advanced materials (Weinheim) (01-11-2018)“…In situ and cytocompatible nanoswitching by external stimuli is highly appealing for reversibly regulating cellular adhesion and functions in vivo. Here, a…”
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Current Knowledge of Th22 Cell and IL-22 Functions in Infectious Diseases
Published in Pathogens (Basel) (23-01-2023)“…T helper 22 (Th22) cells, a newly defined CD4+ T-cell lineage, are characterized by their distinct cytokine profile, which primarily consists of IL-13, IL-22…”
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Orientation-Dependent Mechanical Behaviors of BCC-Fe in Light of the Thermo-Kinetic Synergy of Plastic Deformation
Published in Materials (16-05-2024)“…The orientation-dependent mechanical behaviors of metallic alloys are governed by deformation mechanisms, but the underlying physics remain to be explored. In…”
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Deletion of the Response Regulator PhoP Accelerates the Formation of Aerial Mycelium and Spores in Actinosynnema pretiosum
Published in Frontiers in microbiology (06-04-2022)“…PhoPR is an important two-component signal transduction system (TCS) for microorganisms to sense and respond to phosphate limitation. Although the response…”
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A 3D Fiber‐Hydrogel Based Non‐Viral Gene Delivery Platform Reveals that microRNAs Promote Axon Regeneration and Enhance Functional Recovery Following Spinal Cord Injury
Published in Advanced science (01-08-2021)“…Current treatment approaches toward spinal cord injuries (SCI) have mainly focused on overcoming the inhibitory microenvironment that surrounds lesion sites…”
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Magnetite nanoparticles immobilized Salen Pd (II) as a green catalyst for Suzuki reaction
Published in Catalysis communications (05-09-2012)“…In this work, we described a methodology to immobilize Salen Pd (II) complex on the surface of magnetite nanoparticles. The palladium catalyst exhibited…”
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