Search Results - "Zhang, Kejian"

The genetic fingerprint of susceptibility for transplant-associated thrombotic microangiopathy by Jodele, Sonata, Zhang, Kejian, Zou, Fanggeng, Laskin, Benjamin, Dandoy, Christopher E., Myers, Kasiani C., Lane, Adam, Meller, Jaroslav, Medvedovic, Mario, Chen, Jenny, Davies, Stella M.

“…Transplant-associated thrombotic microangiopathy (TA-TMA) occurs frequently after hematopoietic stem cell transplantation (HSCT) and can lead to significant…”
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Perforin and CD107a testing is superior to NK cell function testing for screening patients for genetic HLH by Rubin, Tamar S., Zhang, Kejian, Gifford, Carrie, Lane, Adam, Choo, Sharon, Bleesing, Jack J., Marsh, Rebecca A.

“…Primary hemophagocytic lymphohistiocytosis (HLH) can be caused by biallelic mutations in PRF1, encoding perforin, or UNC13D, STXBP2, STX11, RAB27A, LYST, and…”
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Hypomorphic mutations in PRF1, MUNC13-4, and STXBP2 are associated with adult-onset familial HLH by Zhang, Kejian, Jordan, Michael B., Marsh, Rebecca A., Johnson, Judith A., Kissell, Diane, Meller, Jarek, Villanueva, Joyce, Risma, Kimberly A., Wei, Qian, Klein, Peter S., Filipovich, Alexandra H.

“…Familial hemophagocytic lymphohistiocytosis (HLH) is a rare primary immunodeficiency disorder characterized by defects in cell-mediated cytotoxicity that…”
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XIAP deficiency: a unique primary immunodeficiency best classified as X-linked familial hemophagocytic lymphohistiocytosis and not as X-linked lymphoproliferative disease by Marsh, Rebecca A., Madden, Lisa, Kitchen, Brenda J., Mody, Rajen, McClimon, Brad, Jordan, Michael B., Bleesing, Jack J., Zhang, Kejian, Filipovich, Alexandra H.

“…X-linked inhibitor of apoptosis (XIAP) deficiency, caused by BIRC4 mutations, is described to cause X-linked lymphoproliferative disease (XLP) phenotypes…”
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Whole‐Exome Sequencing Reveals Overlap Between Macrophage Activation Syndrome in Systemic Juvenile Idiopathic Arthritis and Familial Hemophagocytic Lymphohistiocytosis by Kaufman, Kenneth M., Linghu, Bolan, Szustakowski, Joseph D., Husami, Ammar, Yang, Fan, Zhang, Kejian, Filipovich, Alexandra H., Fall, Ndate, Harley, John B., Nirmala, N. R., Grom, Alexei A.

“…Objective Macrophage activation syndrome (MAS), a life‐threatening complication of systemic juvenile idiopathic arthritis (JIA), resembles familial…”
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Investigation on fabrication process of dissolving microneedle arrays to improve effective needle drug distribution by Wang, Qingqing, Yao, Gangtao, Dong, Pin, Gong, Zihua, Li, Ge, Zhang, Kejian, Wu, Chuanbin

“…[Display omitted] The dissolving microneedle array (DMNA) offers a novel potential approach for transdermal delivery of biological macromolecular drugs and…”
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Whole-Exome Sequencing Reveals Mutations in Genes Linked to Hemophagocytic Lymphohistiocytosis and Macrophage Activation Syndrome in Fatal Cases of H1N1 Influenza by Schulert, Grant S., Zhang, Mingce, Fall, Ndate, Husami, Ammar, Kissell, Diane, Hanosh, Andrew, Zhang, Kejian, Davis, Kristina, Jentzen, Jeffrey M., Napolitano, Lena, Siddiqui, Javed, Smith, Lauren B., Harms, Paul W., Grom, Alexei A., Cron, Randy Q.

“…Background. Severe H1N1 influenza can be lethal in otherwise healthy individuals and can have features of reactive hemophagocytic lymphohistiocytosis (HLH)…”
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X-linked lymphoproliferative syndromes: brothers or distant cousins? by Filipovich, Alexandra H., Zhang, Kejian, Snow, Andrew L., Marsh, Rebecca A.

“…X-linked lymphoproliferative disease (XLP1), described in the mid-1970s and molecularly defined in 1998, and XLP2, reported in 2006, are prematurely lethal…”
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Lifestyle patterns influence the composition of the gut microbiome in a healthy Chinese population by Ren, Yi, Wu, Jiawei, Wang, Yilin, Zhang, Lanying, Ren, Jing, Zhang, Zhiming, Chen, Binghan, Zhang, Kejian, Zhu, Baoli, Liu, Wei, Li, Sabrina, Li, Xu

“…High-throughput sequencing allows for the comprehensive analysis of the human intestinal microbiota. However, extensive association analyses between the…”
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Synthesis of Block Copolymers of Ethylene with Styrene and n-Butyl Acrylate via a Tandem Strategy Combining Ethylene “Living” Polymerization Catalyzed by a Functionalized Pd−Diimine Catalyst with Atom Transfer Radical Polymerization by Zhang, Kejian, Ye, Zhibin, Subramanian, Ramesh

“…We report a new two-step tandem strategy combining two versatile “living” polymerization techniques, Pd−diimine catalyzed ethylene “living” polymerization and…”
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Microbial imbalance in Chinese children with diarrhea or constipation by Ren, Jing, Ren, Yi, Mu, Yu, Zhang, Lanying, Chen, Binghan, Li, Sisi, Fang, Qinyi, Zhang, Zhiming, Zhang, Kejian, Li, Sabrina, Liu, Wei, Cui, Yutao, Li, Xu

“…Diarrhea and constipation are common health concerns in children. Numerous studies have identified strong association between gut microbiota and…”
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Experimental study on color change and compression strength of concrete tunnel lining in a fire by Du, Sheng, Zhang, Yuchun, Sun, Qiang, Gong, Weiyi, Geng, Jishi, Zhang, Kejian

“…•Concrete color turns from dark gray to whitish gray as temperature increasing.•After spraying phenolphthalein, the concrete turn red, the degree of red…”
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Treatment of Chylothorax complicating pulmonary resection with hypertonic glucose Pleurodesis by Zhang, Kejian, Li, Changyuan, Zhang, Mingrui, Li, Yang

“…Abstract Background To retrospectively assess the efficacy of hypertonic glucose pleurodesis for treatment of chylothorax after pulmonary resection. Methods…”
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Nicotine increases apoptosis in HUVECs cultured in high glucose/high fat via Akt ubiquitination and degradation by Cao, Xiaofang, Han, Chunling, Wen, Jinsuo, Guo, Xiaokun, Zhang, Kejian

“…Summary It is well‐documented that nicotine, the main active ingredient in cigarettes, results in endothelial cell injury in numerous diseases. However,…”
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A Trinuclear Pd−Diimine Catalyst for “Core-First” Synthesis of Three-Arm Star Polyethylenes via Ethylene “Living” Polymerization by Zhang, Kejian, Ye, Zhibin, Subramanian, Ramesh

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Acute and 13weeks subchronic toxicological evaluation of naringin in Sprague-Dawley rats by Li, Peibo, Wang, Sheng, Guan, Xiaolin, Liu, Bin, Wang, Yonggang, Xu, Ke, Peng, Wei, Su, Weiwei, Zhang, Kejian

“…•We conducted acute and subchronic oral toxicity studies of naringin.•In the acute study, the oral LD50 was >16g/kg body weight.•No treatment-related…”
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A comprehensive next‐generation sequencing assay for the diagnosis of epidermolysis bullosa by Lucky, Anne W., Dagaonkar, Neha, Lammers, Karen, Husami, Ammar, Kissell, Diane, Zhang, Kejian

“…Background Historically, diagnosis of epidermolysis bullosa has required skin biopsies for electron microscopy, direct immunofluorescence to determine which…”
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Experimental Study on Improving Oil Recovery Mechanism of Injection–Production Coupling in Complex Fault-Block Reservoirs by Zhang, Zhe, Gan, Hongjun, Zhang, Chao, Jia, Shengbin, Yu, Xianzheng, Zhang, Kejian, Zhong, Xinyu, Zheng, Xiaolei, Shen, Tao, Qu, Le, Zhang, Rongjun

“…In order to improve the effect of injection–production coupling development to improve crude oil recovery in complex fault-block reservoirs, we carried out a…”
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Acute and 13 weeks subchronic toxicological evaluation of naringin in Sprague-Dawley rats by Li, Peibo, Wang, Sheng, Guan, Xiaolin, Liu, Bin, Wang, Yonggang, Xu, Ke, Peng, Wei, Su, Weiwei, Zhang, Kejian

“…Naringin is widely distributed in plant foods and has not previously been evaluated for safety through standard in vivo toxicological studies. In the present…”
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Creating China's Biosimilar Drugs Regulatory System: A Calculated Approach by Yang, Jianhong, Zhao, Xiaoyu, Li, Jie, Zhang, Kejian, Zhang, Zheru, Chang, Shunwen, Fu, Daotian, Lyu, Xinhuan, Zhang, Xianglin, Shao, Ying

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