Search Results - "Zhang, Junli"
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Optimization of the heme biosynthesis pathway for the production of 5-aminolevulinic acid in Escherichia coli
Published in Scientific reports (26-02-2015)“…5-Aminolevulinic acid (ALA), the committed intermediate of the heme biosynthesis pathway, shows significant promise for cancer treatment. Here, we identified…”
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Engineering of multiple modular pathways for high-yield production of 5-aminolevulinic acid in Escherichia coli
Published in Bioresource technology (01-02-2019)“…•Balancing the expression of hemA and hemL by mutating RBS improved ALA synthesis.•ALA catabolism was weakened by substituting the promoter of hemB with…”
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Scoparone improves hepatic inflammation and autophagy in mice with nonalcoholic steatohepatitis by regulating the ROS/P38/Nrf2 axis and PI3K/AKT/mTOR pathway in macrophages
Published in Biomedicine & pharmacotherapy (01-05-2020)“…•Scoparone improves hepatic inflammation and autophagy in mice with MCD diet.•Scoparone has an effect on autophag in macrophages, but not…”
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Self-Assembly Synthesis of N‑Doped Carbon Aerogels for Supercapacitor and Electrocatalytic Oxygen Reduction
Published in ACS applied materials & interfaces (17-06-2015)“…The rational design of high-performance and cheap nanomaterials for multiple sustainable energy storage applications is extremely urgent but remains…”
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WAPO-A1 is the causal gene of the 7AL QTL for spikelet number per spike in wheat
Published in PLoS genetics (13-01-2022)“…Improving our understanding of the genes regulating grain yield can contribute to the development of more productive wheat varieties. Previously, a highly…”
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A simple, specific and “on-off” type MUC1 fluorescence aptasensor based on exosomes for detection of breast cancer
Published in Sensors and actuators. B, Chemical (10-12-2018)“…•Tumor-derived exosomes as a novel liquid biopsy biomarker for cancer diagnosis.•MUC-1 is over-expressed on the surface of adenocarcinomas, in particular MCF-7…”
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Identification of a candidate gene for a QTL for spikelet number per spike on wheat chromosome arm 7AL by high-resolution genetic mapping
Published in Theoretical and applied genetics (01-09-2019)“…Key message A high-resolution genetic map combined with haplotype analyses identified a wheat ortholog of rice gene APO1 as the best candidate gene for a 7AL…”
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Lateral organ boundaries 1 is a disease susceptibility gene for citrus bacterial canker disease
Published in Proceedings of the National Academy of Sciences - PNAS (28-01-2014)“…Citrus bacterial canker (CBC) disease occurs worldwide and incurs considerable costs both from control measures and yield losses. Bacteria that cause CBC…”
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Climate change mitigation potential of contaminated land redevelopment: A city-level assessment method
Published in Journal of cleaner production (10-01-2018)“…Under the Paris Agreement, nations and cities are under increasing pressure to reduce greenhouse gas (GHG) emission. Brownfield land redevelopment promises…”
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Role of Hydrophilic Ammonium-Based Deep Eutectic Solvents in SO2 Absorption
Published in Energy & fuels (01-01-2020)“…Acid gases, especially sulfur dioxide (SO2), released from the burning of fossil fuels, have made a great contribution to environmental pollution. However, the…”
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Genetic Architecture of Resistance to Stripe Rust in a Global Winter Wheat Germplasm Collection
Published in G3 : genes - genomes - genetics (01-08-2016)“…Virulence shifts in populations of Puccinia striiformis f. sp. tritici (Pst), the causal pathogen of wheat stripe rust, are a major challenge to resistance…”
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Recent advances in microbial production of δ-aminolevulinic acid and vitamin B12
Published in Biotechnology advances (01-11-2012)“…δ-aminolevulinate (ALA) is an important intermediate involved in tetrapyrrole synthesis (precursor for vitamin B12, chlorophyll and heme) in vivo. It has been…”
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The Role and Mechanism of CREBH Regulating SIRT3 in Metabolic Associated Fatty Liver Disease
Published in Life sciences (1973) (01-10-2022)“…To investigate the effect of cAMP response element-binding protein H (CREBH) on metabolic associated fatty liver disease by regulating sirtuin 3 (SIRT3). Two…”
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A CRISPR-Based Screen Identifies Genes Essential for West-Nile-Virus-Induced Cell Death
Published in Cell reports (Cambridge) (28-07-2015)“…West Nile virus (WNV) causes an acute neurological infection attended by massive neuronal cell death. However, the mechanism(s) behind the virus-induced cell…”
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LINC01343 targets miR-526b-5p to facilitate the development of hepatocellular carcinoma by upregulating ROBO1
Published in Scientific reports (12-10-2023)“…Long noncoding RNAs (lncRNAs) contribute to hepatocellular carcinoma (HCC) progression and development. However, the function and molecular mechanisms of…”
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Identification and Validation of a Nine-Gene Amino Acid Metabolism-Related Risk Signature in HCC
Published in Frontiers in cell and developmental biology (07-09-2021)“…Background: Hepatocellular carcinoma (HCC) is the world’s second most deadly cancer, and metabolic reprogramming is its distinguishing feature. Among…”
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Disseminated cryptococcosis with varicella-zoster virus coinfection of idiopathic CD4 + T lymphocytopenia: a case report and literature review
Published in Virology journal (05-03-2022)“…Idiopathic CD4 + T lymphocytopenia (ICL) is a rare immunodeficiency syndrome, unaccompanied by various opportunistic infections. Cryptococcus and…”
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CREBH knockout accelerates hepatic fibrosis in mouse models of diet-induced nonalcoholic fatty liver disease
Published in Life sciences (1973) (01-08-2020)“…The primary focus of this study was to explore the effects of cyclic AMP response element-binding protein H (CREBH) on the development of nonalcoholic fatty…”
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SREBP-1 has a prognostic role and contributes to invasion and metastasis in human hepatocellular carcinoma
Published in International journal of molecular sciences (25-04-2014)“…Sterol regulatory element-binding protein 1 (SREBP-1) is a well-known nuclear transcription factor involved in lipid synthesis. Recent studies have focused on…”
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An equivalent marginal cost-pricing model for the district heating market
Published in Energy policy (01-12-2013)“…District heating pricing is a core element in reforming the heating market. Existing district heating pricing methods, such as the cost-plus pricing method and…”
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