Search Results - "Zhang, Jiasi Vicky"

High-Affinity Chimeric Antigen Receptor With Cross-Reactive scFv to Clinically Relevant EGFR Oncogenic Isoforms by Thokala, Radhika, Binder, Zev A., Yin, Yibo, Zhang, Logan, Zhang, Jiasi Vicky, Zhang, Daniel Y., Milone, Michael C., Ming, Guo-li, Song, Hongjun, O’Rourke, Donald M.

“…Tumor heterogeneity is a key reason for therapeutic failure and tumor recurrence in glioblastoma (GBM). Our chimeric antigen receptor (CAR) T cell (2173 CAR T…”
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Neurofilament Light Chain Is Related to Longitudinal Decline in Frontotemporal Lobar Degeneration

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Selective removal of misfolded SOD1 delays disease onset in a mouse model of amyotrophic lateral sclerosis by Guan, Teng, Zhou, Ting, Zhang, Xiaosha, Guo, Ying, Yang, Chaoxian, Lin, Justin, Zhang, Jiasi Vicky, Cheng, Yongquan, Marzban, Hassan, Wang, Yu Tian, Kong, Jiming

“…Background Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease. There is no cure currently. The discovery that mutations in the gene…”
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Locally secreted BiTEs complement CAR T cells by enhancing killing of antigen heterogeneous solid tumors by Yin, Yibo, Rodriguez, Jesse L., Li, Nannan, Thokala, Radhika, Nasrallah, MacLean P., Hu, Li, Zhang, Logan, Zhang, Jiasi Vicky, Logun, Meghan T., Kainth, Devneet, Haddad, Leila, Zhao, Yang, Wu, Tong, Johns, Emily X., Long, Yu, Liang, Hongsheng, Qi, Jiping, Zhang, Xiangtong, Binder, Zev A., Lin, Zhiguo, O’Rourke, Donald M.

“…Bispecific T cell engagers (BiTEs) are bispecific antibodies that redirect T cells to target antigen-expressing tumors. We hypothesized that BiTE-secreting…”
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Single-cell RNA-seq-based proteogenomics identifies glioblastoma-specific transposable elements encoding HLA-I-presented peptides by Bonté, Pierre-Emmanuel, Arribas, Yago A, Merlotti, Antonela, Carrascal, Montserrat, Zhang, Jiasi Vicky, Zueva, Elina, Binder, Zev A, Alanio, Cécile, Goudot, Christel, Amigorena, Sebastian

“…We analyze transposable elements (TEs) in glioblastoma (GBM) patients using a proteogenomic pipeline that combines single-cell transcriptomics, bulk RNA…”
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Armored bicistronic CAR T cells with dominant-negative TGF-β receptor II to overcome resistance in glioblastoma by Li, Nannan, Rodriguez, Jesse L, Yin, Yibo, Logun, Meghan T, Zhang, Logan, Yu, Shengkun, Hicks, Kelly A, Zhang, Jiasi Vicky, Zhang, Laura, Xie, Chuncheng, Wang, Jiabin, Wang, Tianyu, Xu, Jiayi, Fraietta, Joseph A, Binder, Zev A, Lin, Zhiguo, O'Rourke, Donald M

“…Chimeric antigen receptor (CAR) T cells have shown significant efficacy in hematological diseases. However, CAR T therapy has demonstrated limited efficacy in…”
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Immunologic Features in De Novo and Recurrent Glioblastoma Are Associated with Survival Outcomes by Alanio, Cécile, Binder, Zev A, Chang, Renee B, Nasrallah, MacLean P, Delman, Devora, Li, Joey H, Tang, Oliver Y, Zhang, Logan Y, Zhang, Jiasi Vicky, Wherry, E John, O'Rourke, Donald M, Beatty, Gregory L

“…Glioblastoma (GBM) is an immunologically "cold" tumor characterized by poor responsiveness to immunotherapy. Standard of care for GBM is surgical resection…”
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Neurofilament Light Chain Related to Longitudinal Decline in Frontotemporal Lobar Degeneration by Zhang, Jiasi Vicky, Irwin, David J., Blennow, Kaj, Zetterberg, Henrik, Lee, Edward B., Shaw, Leslie M., Rascovsky, Katya, Massimo, Lauren, McMillan, Corey T., Chen-Plotkin, Alice, Elman, Lauren, Lee, Virginia M.-Y., McCluskey, Leo, Toledo, Jon B., Weintraub, Daniel, Wolk, David, Trojanowski, John Q., Grossman, Murray

“…Accurate diagnosis and prognosis of frontotemporal lobar degeneration (FTLD) during life is an urgent concern in the context of emerging disease-modifying…”
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