Search Results - "Zhang, Jennifer Y."

The JNK Signaling Pathway in Inflammatory Skin Disorders and Cancer by Hammouda, Manel B, Ford, Amy E, Liu, Yuan, Zhang, Jennifer Y

“…The c-Jun N-terminal kinases (JNKs), with its members JNK1, JNK2, and JNK3, is a subfamily of (MAPK) mitogen-activated protein kinases. JNK signaling regulates…”
Get full text

Transient Receptor Potential Vanilloid 4 Ion Channel Functions as a Pruriceptor in Epidermal Keratinocytes to Evoke Histaminergic Itch by Chen, Yong, Fang, Quan, Wang, Zilong, Zhang, Jennifer Y., MacLeod, Amanda S., Hall, Russell P., Liedtke, Wolfgang B.

“…TRPV4 ion channels function in epidermal keratinocytes and in innervating sensory neurons; however, the contribution of the channel in either cell to…”
Get full text

UBE2N Promotes Melanoma Growth via MEK/FRA1/SOX10 Signaling by Dikshit, Anushka, Jin, Yingai J, Degan, Simone, Hwang, Jihwan, Foster, Matthew W, Li, Chuan-Yuan, Zhang, Jennifer Y

“…UBE2N is a K63-specific ubiquitin conjugase linked to various immune disorders and cancer. Here, we demonstrate that UBE2N and its partners UBE2V1 and UBE2V2…”
Get full text

Location bias contributes to functionally selective responses of biased CXCR3 agonists by Eiger, Dylan Scott, Boldizsar, Noelia, Honeycutt, Christopher Cole, Gardner, Julia, Kirchner, Stephen, Hicks, Chloe, Choi, Issac, Pham, Uyen, Zheng, Kevin, Warman, Anmol, Smith, Jeffrey S., Zhang, Jennifer Y., Rajagopal, Sudarshan

“…Some G protein-coupled receptor (GPCR) ligands act as “biased agonists” that preferentially activate specific signaling transducers over others. Although GPCRs…”
Get full text

Continuous Glucose Monitoring in the Hospital by Perez-Guzman, M Citlalli, Shang, Trisha, Zhang, Jennifer Y, Jornsay, Donna, Klonoff, David C

“…Continuous glucose monitors (CGMs) have suddenly become part of routine care in many hospitals. The coronavirus disease 2019 (COVID-19) pandemic has…”
Get full text

Corrigendum: Co-treatment of chloroquine and trametinib inhibits melanoma cell proliferation and decreases immune cell infiltration by Degan, Simone, May, Brian L, Jin, Yingai J, Ben Hammouda, Manel, Sun, Huiying, Zhang, Guoqiang, Wang, Yan, Erdmann, Detlev, Warren, Warren, Zhang, Jennifer Y

“…[This corrects the article DOI: 10.3389/fonc.2022.782877.]…”
Get full text

Diabetes Research and Resource Sharing During the COVID-19 Pandemic: A Systematic Review and Experience from an Academic/Non-Profit Resource Website by Yeung, Andrea M., Dirisanala, Sudha, Abraham, Amalia, Huang, Jingtong, Brennan, Grayson M., Urrutia, María Agustina, Baran, Jesica D., Nguyen, Kevin T., Xu, Nicole Y., Shang, Trisha, Zhang, Jennifer Y., Klonoff, David C., Davis, Georgia M., Pasquel, Francisco J.

“…Background: The magnitude of the response of the diabetes professional community to the COVID-19 pandemic is not known. We aimed to examine diabetes technology…”
Get full text

Co-Treatment of Chloroquine and Trametinib Inhibits Melanoma Cell Proliferation and Decreases Immune Cell Infiltration by Degan, Simone, May, Brian L, Jin, Yingai J, Hammoda, Manel Ben, Sun, Huiying, Zhang, Guoqiang, Wang, Yan, Erdmann, Detlev, Warren, Warren, Zhang, Jennifer Y

“…Autophagy is characterized as a cytoprotective process and inhibition of autophagy with medicinally active agents, such as chloroquine (CQ) is proposed as a…”
Get full text

IL-27 Derived From Macrophages Facilitates IL-15 Production and T Cell Maintenance Following Allergic Hypersensitivity Responses by Suwanpradid, Jutamas, Lee, Min Jin, Hoang, Peter, Kwock, Jeffery, Floyd, Lauren P, Smith, Jeffrey S, Yin, Zhinan, Atwater, Amber R, Rajagopal, Sudarshan, Kedl, Ross M, Corcoran, David L, Zhang, Jennifer Y, MacLeod, Amanda S

“…Crosstalk between T cells, dendritic cells, and macrophages in temporal leukocyte clusters within barrier tissues provides a new concept for T cell activation…”
Get full text

Clinical decision support to Optimize Care of patients with Atrial Fibrillation or flutter in the Emergency department: protocol of a stepped-wedge cluster randomized pragmatic trial (O'CAFÉ trial) by Vinson, David R, Rauchwerger, Adina S, Karadi, Chandu A, Shan, Judy, Warton, E Margaret, Zhang, Jennifer Y, Ballard, Dustin W, Mark, Dustin G, Hofmann, Erik R, Cotton, Dale M, Durant, Edward J, Lin, James S, Sax, Dana R, Poth, Luke S, Gamboa, Stephen H, Ghiya, Meena S, Kene, Mamata V, Ganapathy, Anuradha, Whiteley, Patrick M, Bouvet, Sean C, Babakhanian, Leon, Kwok, Edward W, Solomon, Matthew D, Go, Alan S, Reed, Mary E

“…Management of adults with atrial fibrillation (AF) or atrial flutter in the emergency department (ED) includes rate reduction, cardioversion, and stroke…”
Get full text

Single-Cell RNA Sequencing Reveals Cellular and Transcriptional Changes Associated With M1 Macrophage Polarization in Hidradenitis Suppurativa by Mariottoni, Paula, Jiang, Simon W, Prestwood, Courtney A, Jain, Vaibhav, Suwanpradid, Jutamas, Whitley, Melodi Javid, Coates, Margaret, Brown, David A, Erdmann, Detlev, Corcoran, David L, Gregory, Simon G, Jaleel, Tarannum, Zhang, Jennifer Y, Harris-Tryon, Tamia A, MacLeod, Amanda S

“…Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease characterized by recurrent abscesses, nodules, and sinus tracts in areas of high hair…”
Get full text

Biological, molecular and pharmacological characteristics of chloroquine, hydroxychloroquine, convalescent plasma, and remdesivir for COVID-19 pandemic: A comparative analysis by Meo, Sultan Ayoub, Zaidi, Syed Ziauddin A., Shang, Trisha, Zhang, Jennifer Y., Al-Khlaiwi, Thamir, Bukhari, Ishfaq A., Akram, Javed, Klonoff, David C.

“…The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection, also known as COVID-19 pandemic has caused an alarming situation worldwide. Since…”
Get full text

An aging-susceptible circadian rhythm controls cutaneous antiviral immunity by Kirchner, Stephen J, Lei, Vivian, Kim, Paul T, Patel, Meera, Shannon, Jessica L, Corcoran, David, Hughes, Dalton, Waters, Diana K, Dzirasa, Kafui, Erdmann, Detlev, Coers, Jörn, MacLeod, Amanda S, Zhang, Jennifer Y

“…Aged skin is prone to viral infections, but the mechanisms responsible for this immunosenescent immune risk are unclear. We observed that aged murine and human…”
Get full text

Keratinocyte Growth Regulation TRP-ed Up Over Downregulated TRPV4? by Liedtke, Wolfgang, Zhang, Jennifer Y., Hall, Russell P., Steinhoff, Martin

“…This commentary on an exciting new study (Fusi et al., 2014) puts the finding of TRPV4 downregulation in several nonmelanoma skin cancers into context. The…”
Get full text

The c-Jun NH2-terminal kinase 2 plays a dominant role in human epidermal neoplasia by Ke, Hengning, Harris, Rebecca, Coloff, Jonathan L, Jin, Jane Y, Leshin, Benjamin, Miliani de Marval, Paula, Tao, Shiying, Rathmell, Jeffrey C, Hall, Russell P, Zhang, Jennifer Y

“…The c-Jun NH(2)-terminal kinase (JNK) signaling cascade has been implicated in a wide range of diseases, including cancer. It is unclear how different JNK…”
Get full text

Single-cell landscape analysis unravels molecular programming of the human B cell compartment in chronic GVHD by Poe, Jonathan C, Fang, Jiyuan, Zhang, Dadong, Lee, Marissa R, DiCioccio, Rachel A, Su, Hsuan, Qin, Xiaodi, Zhang, Jennifer Y, Visentin, Jonathan, Bracken, Sonali J, Ho, Vincent T, Wang, Kathy S, Rose, Jeremy J, Pavletic, Steven Z, Hakim, Frances T, Jia, Wei, Suthers, Amy N, Curry-Chisolm, Itaevia M, Horwitz, Mitchell E, Rizzieri, David A, McManigle, William C, Chao, Nelson J, Cardones, Adela R, Xie, Jichun, Owzar, Kouros, Sarantopoulos, Stefanie

“…Alloreactivity can drive autoimmune syndromes. After allogeneic hematopoietic stem cell transplantation (allo-HCT), chronic graft-versus-host disease (cGVHD),…”
Get full text

Potential Utility of Synthetic D-Lactate Polymers in Skin Cancer by Dikshit, Anushka, Lu, Junqi, Ford, Amy E., Degan, Simone, Jin, Yingai J., Sun, Huiying, Nichols, Amanda, Salama, April K.S., Beasley, Georgia, Gooden, David, Zhang, Jennifer Y.

“…Increased breakdown of glucose through glycolysis in both aerobic and anaerobic conditions is a hallmark feature of mammalian cancer and leads to increased…”
Get full text

CYLD inhibits tumorigenesis and metastasis by blocking JNK/AP1 signaling at multiple levels by Miliani de Marval, Paula, Lutfeali, Shazia, Jin, Jane Y, Leshin, Benjamin, Selim, M Angelica, Zhang, Jennifer Y

“…CYLD has been recognized as a tumor suppressor due to its dominant genetic linkage to multiple types of epidermal tumors and a range of other cancers. The…”
Get full text

Tumor necrosis factor receptor 1/c-Jun-NH2-Kinase signaling promotes human neoplasia by ZHANG, Jennifer Y, ADAMS, Amy E, RIDKY, Todd W, SHIYING TAO, KHAVARI, Paul A

“…The tumor necrosis factor alpha receptor (TNFR1) activates downstream effectors that include the mitogen-activated protein kinase kinase 7…”
Get full text

Divergent gene regulation and growth effects by NF-κB in epithelial and mesenchymal cells of human skin by HINATA, Kaede, GERVIN, Adam M, ZHANG, Y. Jennifer, KHAVARI, Paul A

“…NF-kappa B regulates normal and pathological processes, including neoplasia, in a tissue-context-dependent manner. In skin, NF-kappa B is implicated in…”
Get full text