Search Results - "Zhang, Jennifer R."
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A highly potent long-acting small-molecule HIV-1 capsid inhibitor with efficacy in a humanized mouse model
Published in Nature medicine (01-09-2019)“…People living with HIV (PLWH) have expressed concern about the life-long burden and stigma associated with taking pills daily and can experience medication…”
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Journal Article -
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Discovery of Hepatitis B Virus Surface Antigen Suppressor GS-8873
Published in ACS medicinal chemistry letters (11-04-2024)“…Chronic hepatitis B (CHB) virus infection afflicts hundreds of millions of people and causes nearly one million deaths annually. The high levels of circulating…”
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Effect of Isolation of Periosteum and Dura on the Healing of Rabbit Calvarial Inlay Bone Grafts
Published in Plastic and reconstructive surgery (1963) (01-02-2001)“…Little is understood about the role of the recipient site in the revascularization and incorporation of autogenous inlay bone grafts in the craniofacial…”
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simple in vitro culture system for tracheal cartilage development
Published in In vitro cellular & developmental biology. Animal (01-02-2010)“…Semi-circular tracheal cartilage is a critical determinant of maintaining architectural integrity of the respiratory airway. The current effort to understand…”
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Optimization of Pharmacokinetics through Manipulation of Physicochemical Properties in a Series of HCV Inhibitors
Published in ACS medicinal chemistry letters (13-10-2011)“…A novel series of HCV replication inhibitors based on a pyrido[3,2-d]pyrimidine core were optimized for pharmacokinetics (PK) in rats. Several associations…”
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Regulation of Sox9 by Sonic Hedgehog (Shh) is essential for patterning and formation of tracheal cartilage
Published in Developmental dynamics (01-02-2010)“…We report that Sonic Hedgehog (Shh) regulates both formation and patterning of tracheal cartilage by controlling the expression pattern and level of the…”
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7
Clinical targeting of HIV capsid protein with a long-acting small molecule
Published in Nature (London) (27-08-2020)“…Oral antiretroviral agents provide life-saving treatments for millions of people living with HIV, and can prevent new infections via pre-exposure prophylaxis 1…”
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Journal Article -
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ΔNp63 plays an anti-apoptotic role in ventral bladder development
Published in Development (Cambridge) (01-12-2006)“…The bladder, the largest smooth-muscle organ in the human body, is responsible for urine storage and micturition. P63, a homolog of the p53 tumor-suppressor…”
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Journal Article -
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The role of Shh transcription activator Gli2 in chick cloacal development
Published in Developmental biology (15-03-2007)“…Patterning and differentiation along the dorsal–ventral (D–V) axis lead to cloacal partitioning into ventral urinary and dorsal alimentary tracts in most…”
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Journal Article -
10
DeltaNp63 plays an anti-apoptotic role in ventral bladder development
Published in Development (Cambridge) (01-12-2006)“…The bladder, the largest smooth-muscle organ in the human body, is responsible for urine storage and micturition. P63, a homolog of the p53 tumor-suppressor…”
Get full text
Journal Article -
11
ÎNp63 plays an anti-apoptotic role in ventral bladder development
Published in Development (Cambridge) (01-12-2006)“…The bladder, the largest smooth-muscle organ in the human body, is responsible for urine storage and micturition. P63, a homolog of the p53 tumor-suppressor…”
Get full text
Journal Article