Search Results - "Zhang, Hui‐Zhong"
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The Roles of CD73 in Cancer
Published in BioMed research international (01-01-2014)“…Purinergic signaling has emerged as an important player in cancer progression and is regulated by a series of nucleotidases. Among the enzyme cascade, CD73,…”
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2
CD73 promotes proliferation and migration of human cervical cancer cells independent of its enzyme activity
Published in BMC cancer (15-02-2017)“…CD73 has both enzymatic and non-enzymatic functions in cells. As a nucleotidase, CD73 plays its enzymatic function by catalyzing the hydrolysis of AMP into…”
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3
miR-665 expression predicts poor survival and promotes tumor metastasis by targeting NR4A3 in breast cancer
Published in Cell death & disease (17-06-2019)“…Cancer metastasis is the main cause of death in breast cancer (BC) patients. Therefore, prediction and treatment of metastasis is critical for enhancing the…”
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4
Phosphorylation of androgen receptor by mTORC1 promotes liver steatosis and tumorigenesis
Published in Hepatology (Baltimore, Md.) (01-05-2022)“…Background and Aims Androgen receptor (AR) has been reported to play an important role in the development and progression of man’s prostate cancer…”
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5
Astrocyte Elevated Gene-1 is a Novel Prognostic Marker for Breast Cancer Progression and Overall Patient Survival
Published in Clinical cancer research (01-06-2008)“…Purpose: The present study was aimed at clarifying the expression of astrocyte elevated gene-1 ( AEG-1 ), one of the target genes of oncogenic Ha-ras, in…”
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6
Distinct Roles of Adenosine Deaminase Isoenzymes ADA1 and ADA2: A Pan-Cancer Analysis
Published in Frontiers in immunology (18-05-2022)“…Adenosine deaminase (ADA) plays an important role in immune response, which includes two isoenzymes: ADA1 and ADA2. This study aims to explore the roles of…”
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Clinical Significance and Prognostic Value of microRNA Expression Signatures in Hepatocellular Carcinoma
Published in Clinical cancer research (01-09-2013)“…MicroRNAs (miRNAs) play important roles in the development and progression of cancer. The aim of this study is to identify miRNA expression signatures in…”
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8
CD73 Severed as a Potential Prognostic Marker and Promote Lung Cancer Cells Migration via Enhancing EMT Progression
Published in Frontiers in genetics (17-11-2021)“…To investigate the expression levels and prognostic value of CD73 in lung cancer. And moreover, to identify the effect and potential mechanism of CD73 on lung…”
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3D printed poly(ε-caprolactone) scaffolds function with simvastatin-loaded poly(lactic-co-glycolic acid) microspheres to repair load-bearing segmental bone defects
Published in Experimental and therapeutic medicine (01-01-2019)“…Repairing critical-sized bone defects has been a major challenge for orthopedic surgeons in the clinic. The generation of functioning bone tissue scaffolds…”
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10
Hepatitis B virus infection is associated with younger median age at diagnosis and death in cancers
Published in International journal of cancer (01-07-2017)“…Several non‐hepatocellular cancers were linked with hepatitis B virus (HBV) infection. This study was aimed to quantify the potential associations between HBV…”
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The genomic architecture of EBV and infected gastric tissue from precursor lesions to carcinoma
Published in Genome medicine (07-09-2021)“…Epstein-Barr virus (EBV)-associated gastric carcinomas (EBVaGCs) present unique molecular signatures, but the tumorigenesis of EBVaGCs and the role EBV plays…”
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12
Alternative Splicing Regulation of Glycine-Rich Proteins via Target of Rapamycin-Reactive Oxygen Species Pathway in Arabidopsis Seedlings Upon Glucose Stress
Published in Frontiers in plant science (15-04-2022)“…Glucose can serve as both the source of energy and regulatory signaling molecule in plant. Due to the environmental and metabolic change, sugar levels could…”
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13
C2‐mediated decrease in DNA methylation, accumulation of siRNAs, and increase in expression for genes involved in defense pathways in plants infected with beet severe curly top virus
Published in The Plant journal : for cell and molecular biology (01-03-2013)“…Summary Cytosine methylation is one of epigenetic information marked on the DNA sequence. In plants, small interfering RNAs (siRNAs) target homologous genomic…”
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14
Apoptosis drives cancer cells proliferate and metastasize
Published in Journal of cellular and molecular medicine (01-01-2013)“…Cancer has been considered to be the result of accumulated gene mutations, which result in uncontrolled cell proliferations for a long time. Cancers are also…”
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LncRNA CSMD1-1 promotes the progression of Hepatocellular Carcinoma by activating MYC signaling
Published in Theranostics (01-01-2020)“…Emerging evidence suggests that long non-coding RNAs (lncRNA) play critical roles in the development and progression of diverse cancers including…”
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EIF4EBP1 overexpression is associated with poor survival and disease progression in patients with hepatocellular carcinoma
Published in PloS one (06-02-2015)“…EIF4EBP1 acts as a crucial effector in mTOR signaling pathway. Studies have suggested that EIF4EBP1 plays a critical role in carcinogenesis. However, the…”
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microRNA-217 inhibits tumor progression and metastasis by downregulating EZH2 and predicts favorable prognosis in gastric cancer
Published in Oncotarget (10-05-2015)“…microRNA-217 (miR-217) is frequently dysregulated in cancer. Here, we report that miR-217 levels were lower in tumor tissue compared with the adjacent normal…”
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18
Serum adenosine deaminase activity is increased in systemic lupus erythematosus patients and correlated with disease activity
Published in Immunologic research (01-04-2018)“…Adenosine deaminase (ADA) has been found to be involved in autoimmune disease progression. To assess the potential application of serum ADA activity in…”
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Long-Term Tri-Modal In Vivo Tracking of Engrafted Cartilage-Derived Stem/Progenitor Cells Based on Upconversion Nanoparticles
Published in Biomolecules (Basel, Switzerland) (29-06-2021)“…Cartilage-derived stem/progenitor cells (CSPCs) are a potential choice for seed cells in osteal and chondral regeneration, and the outcomes of their survival…”
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20
Precise microdissection of gastric mixed adeno-neuroendocrine carcinoma dissects its genomic landscape and evolutionary clonal origins
Published in Cell reports (Cambridge) (27-06-2023)“…Gastric mixed adenoneuroendocrine carcinoma (MANEC) is a clinically aggressive and heterogeneous tumor composed of adenocarcinoma (ACA) and neuroendocrine…”
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