Search Results - "Zhang, Huazheng"

A comprehensive review of the structure elucidation and biological activity of triterpenoids from Ganoderma spp by Xia, Qing, Zhang, Huazheng, Sun, Xuefei, Zhao, Haijuan, Wu, Lingfang, Zhu, Dan, Yang, Guanghui, Shao, Yanyan, Zhang, Xiaoxue, Mao, Xin, Zhang, Lanzhen, She, Gaimei

“…Ganoderma triterpenes (GTs) are the major secondary metabolites of Ganoderma lucidum, a traditional Chinese medicine, popularly used for complementary cancer…”
Get full text

Lithospermic acid promotes angiogenesis in zebrafish and HUVECs by regulating the VEGF/PI3K-Akt/MAPK signaling pathways by Liang, Qiuxia, Zhang, Huazheng, Han, Cong, Chen, Xiqiang, Zhang, Yun, He, Qiuxia, Sun, Chen, Liu, Kechun, Li, Weidong, Xia, Qing

“…[Display omitted] •Lithospermic acid (LA) promoted the length of vessels in zebrafish.•LA promoted the proliferation and migration of HUVECs under…”
Get full text

Amino acid derivatives of ligustrazine-oleanolic acid as new cytotoxic agents by Chu, Fuhao, Xu, Xin, Li, Guoliang, Gu, Shun, Xu, Kuo, Gong, Yan, Xu, Bing, Wang, Mina, Zhang, Huazheng, Zhang, Yuzhong, Wang, Penglong, Lei, Haimin

“…A series of novel ligustrazine-oleanolic acid (TOA) derivatives were designed, and synthesized by conjugating amino acids to the 3-hydroxy group of TOA by…”
Get full text

Ligustrazine-Oleanolic Acid Glycine Derivative, G-TOA, Selectively Inhibited the Proliferation and Induced Apoptosis of Activated HSC-T6 Cells by Bi, Siling, Chu, Fuhao, Wang, Mina, Li, Bi, Mao, Pei, Zhang, Huazheng, Wang, Penglong, Guo, Wenbo, Xu, Liang, Ren, Liwei, Lei, Haimin, Zhang, Yuzhong

“…Hepatic fibrosis is a naturally occurring wound-healing reaction, with an imbalance of extracellular matrix (ECM) during tissue repair response, which can…”
Get full text

Proliferative Activity and Neuroprotective Effect of Ligustrazene Derivative by Irritation of Vascular Endothelial Growth Factor Expression in Middle Cerebral Artery Occlusion Rats by Zhang, Huazheng, Wang, Penglong, Ren, Liwei, Wang, Xiaobo, Li, Guoliang, Wang, Mina, Chu, Fuhao, Gong, Yan, Xu, Bing, Bi, Siling, Lei, Haimin, Zhang, Yuzhong

“…Purpose: To investigate the proliferative activity and neuroprotective effect of a newly identified ligustrazine derivative…”
Get full text

Isoliquiritigenin triggers developmental toxicity and oxidative stress–mediated apoptosis in zebrafish embryos/larvae via Nrf2-HO1/JNK-ERK/mitochondrion pathway by Song, Zhenzhen, Zhang, Yun, Zhang, Huazheng, Rajendran, R. Samuel, Wang, Rongchun, Hsiao, Chung-Der, Li, Jianheng, Xia, Qing, Liu, Kechun

“…Isoliquiritigenin (ISL) is an emerging natural flavonoid found in the roots of licorice, exhibits antioxidant, anti-cancer, anti-inflammatory, anti-allergic,…”
Get full text

Novel synthesis of Abaloparatide: Advancing osteoporosis treatment in postmenopausal women by Zhang, Na, Zhang, Huazheng, Teng, Yuetai, Yin, Xiaoxue, Niu, Weihong, Qin, Yinhui, Xu, Nan

“…[Display omitted] •Soluble hydrophobic support-assisted liquid-phase synthesis technology of Abaloparatide.•Conditions of removing support Tag-OH.•Improving…”
Get full text

A reputation mechanism based Deep Reinforcement Learning and blockchain to suppress selfish node attack motivation in Vehicular Ad-Hoc Network by Zhang, Bowei, Wang, Xiaoliang, Xie, Ru, Li, Chuncao, Zhang, Huazheng, Jiang, Frank

“…The selfish On-Board-Unit (OBU) attacks Vehicular Ad-Hoc Network (VANET) by various attacks for profit. However, many existing methods are based on the…”
Get full text

Xinkeshu tablets promote angiogenesis in zebrafish embryos and human umbilical vein endothelial cells through multiple signaling pathways by Liu, Qing, Zhang, Huazheng, An, Ying, Zhang, Yun, He, Qiuxia, Liu, Kechun, Xia, Qing, Zhou, Honglei

“…Angiogenesis is particularly important in ischemic cardiovascular diseases such as coronary heart disease (CHD). Xinkeshu tablets (XKS) are a commonly used…”
Get full text

Investigation of the chemical profile and anti-inflammatory mechanisms of flavonoids from Artemisia vestita Wall. ex Besser via targeted metabolomics, zebrafish model, and network pharmacology by Zhou, Chaoyi, Chen, Jing, Zhang, Huazheng, Zhang, Shanshan, Zhang, Yun, Liu, Kechun, Mi, Ma, Xia, Qing

“…Artemisia vestita Wall. ex Besser is wildly distributed in the western high-altitude area of China and has been used as a Tibetan medicine to treat…”
Get full text

Toosendanin triggered hepatotoxicity in zebrafish via inflammation, autophagy, and apoptosis pathways by Sun, Meng, Liu, Qing, Liang, Qiuxia, Gao, Shuo, Zhuang, Kaiyan, Zhang, Yun, Zhang, Huazheng, Liu, Kechun, She, Gaimei, Xia, Qing

“…Toosendanin (TSN) is a crucial component from Toosendan Fructus with a promising anti-tumor capacity. It is also the primary suspect hepatotoxic component of…”
Get full text

Demo:Dynamic Suppression of Selfish Node Attack Motivation in the Process of VANET Communication by Zhang, Bowei, Wang, Xiaoliang, Xie, Ru, Zhang, Huazheng, Jiang, Frank

“…The selfish On-Board-Unit (OBU) attacks Vehicular Ad-Hoc Network (VANET) by various attacks for profit. However, many existing methods are based on the…”
Get full text

Neuroprotection by new ligustrazine-cinnamon acid derivatives on CoCl2-induced apoptosis in differentiated PC12 cells by Wang, Penglong, Zhao, Rui, Yan, Wenqiang, Zhang, Xinyu, Zhang, Huazheng, Xu, Bing, Chu, Fuhao, Han, Yaotian, Li, Guoliang, Liu, Wei, Zhang, Yuzhong, Lei, Haimin

“…[Display omitted] •Ligustrazine-cinnamon acid derivatives exhibited promising neur-protective activity.•3a showed the most promising potency with the IC50…”
Get full text

Bile acids, carriers of hepatoma-targeted drugs? by Gong, Yan, Zhang, Xiaoqian, Zhang, Yuzhong, Chu, Fuhao, Li, Guoliang, Zhang, Haibo, Xu, Bing, Zhang, Huazheng, Li, Bi, Wang, Penglong, Lei, Haimin

“…Previous studies display that bile acids (Bas) could be used as carriers and pharmaceutical excipients. In this study, the selective cytotoxicity of 6 bile…”
Get more information

Ligustrazinyl amides: a novel class of ligustrazine-phenolic acid derivatives with neuroprotective effects by Li, Guoliang, Xu, Xin, Xu, Kuo, Chu, Fuhao, Song, Jixiang, Zhou, Shen, Xu, Bing, Gong, Yan, Zhang, Huazheng, Zhang, Yuzhong, Wang, Penglong, Lei, Haimin

“…Background Ligustrazine has potent effects of thrombolysis, neuroprotection and vascular protection, which were important for effectively protecting the…”
Get full text

Neuroprotection by new ligustrazine-cinnamon acid derivatives on CoCl 2 -induced apoptosis in differentiated PC12 cells by Wang, Penglong, Zhao, Rui, Yan, Wenqiang, Zhang, Xinyu, Zhang, Huazheng, Xu, Bing, Chu, Fuhao, Han, Yaotian, Li, Guoliang, Liu, Wei, Zhang, Yuzhong, Lei, Haimin

“…A new series of ligustrazine-cinnamon acid derivatives had been designed and synthesized as potential neuro-protective agents. Among the derivatives, 3a…”
Get full text

Methodology of Adapting Large English Language Models for Specific Cultural Contexts by Zhang, Wenjing, Xiao, Siqi, Lei, Xuejiao, Wang, Ning, Zhang, Huazheng, An, Meijuan, Yang, Bikun, Liu, Zhaoxiang, Wang, Kai, Lian, Shiguo

“…The rapid growth of large language models(LLMs) has emerged as a prominent trend in the field of artificial intelligence. However, current state-of-the-art…”
Get full text

Research of Dynamic Time-of-use Tariffs for PEV Charging Stations Based on User Behavior Habits by Wang, Yali, Wang, Ranran, Zhang, Huazheng

“…With the rapid development of electric vehicle technology and the constant improvement of the people environmental protection consciousness, the scale of…”
Get full text